BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

356 related articles for article (PubMed ID: 16778189)

  • 1. Oncogenic function of a novel WD-domain protein, STRAP, in human carcinogenesis.
    Halder SK; Anumanthan G; Maddula R; Mann J; Chytil A; Gonzalez AL; Washington MK; Moses HL; Beauchamp RD; Datta PK
    Cancer Res; 2006 Jun; 66(12):6156-66. PubMed ID: 16778189
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Oncogenic serine-threonine kinase receptor-associated protein modulates the function of Ewing sarcoma protein through a novel mechanism.
    Anumanthan G; Halder SK; Friedman DB; Datta PK
    Cancer Res; 2006 Nov; 66(22):10824-32. PubMed ID: 17108118
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Smad7 induces tumorigenicity by blocking TGF-beta-induced growth inhibition and apoptosis.
    Halder SK; Beauchamp RD; Datta PK
    Exp Cell Res; 2005 Jul; 307(1):231-46. PubMed ID: 15922743
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Transforming growth factor beta signaling via Ras in mesenchymal cells requires p21-activated kinase 2 for extracellular signal-regulated kinase-dependent transcriptional responses.
    Suzuki K; Wilkes MC; Garamszegi N; Edens M; Leof EB
    Cancer Res; 2007 Apr; 67(8):3673-82. PubMed ID: 17440079
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ELAC2, a putative prostate cancer susceptibility gene product, potentiates TGF-beta/Smad-induced growth arrest of prostate cells.
    Noda D; Itoh S; Watanabe Y; Inamitsu M; Dennler S; Itoh F; Koike S; Danielpour D; ten Dijke P; Kato M
    Oncogene; 2006 Sep; 25(41):5591-600. PubMed ID: 16636667
    [TBL] [Abstract][Full Text] [Related]  

  • 6. TGF-beta regulates differentially the proliferation of fetal and adult human skin fibroblasts via the activation of PKA and the autocrine action of FGF-2.
    Giannouli CC; Kletsas D
    Cell Signal; 2006 Sep; 18(9):1417-29. PubMed ID: 16361081
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cooperation of H2O2-mediated ERK activation with Smad pathway in TGF-beta1 induction of p21WAF1/Cip1.
    Kim YK; Bae GU; Kang JK; Park JW; Lee EK; Lee HY; Choi WS; Lee HW; Han JW
    Cell Signal; 2006 Feb; 18(2):236-43. PubMed ID: 15979845
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation of extracellular signal-regulated kinase by TGF-beta1 via TbetaRII and Smad7 dependent mechanisms in human bronchial epithelial BEP2D cells.
    Huo YY; Hu YC; He XR; Wang Y; Song BQ; Zhou PK; Zhu MX; Li G; Wu DC
    Cell Biol Toxicol; 2007 Mar; 23(2):113-28. PubMed ID: 17096210
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Farnesyltransferase inhibitor (L-744,832) restores TGF-beta type II receptor expression and enhances radiation sensitivity in K-ras mutant pancreatic cancer cell line MIA PaCa-2.
    Alcock RA; Dey S; Chendil D; Inayat MS; Mohiuddin M; Hartman G; Chatfield LK; Gallicchio VS; Ahmed MM
    Oncogene; 2002 Nov; 21(51):7883-90. PubMed ID: 12420225
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expression of Smad4 in the FaDu cell line partially restores TGF-beta growth inhibition but is not sufficient to regulate fibronectin expression or suppress tumorigenicity.
    Hummer BT; Bartlett C; Henry E; Weissman BE
    J Cell Physiol; 2003 Mar; 194(3):289-302. PubMed ID: 12548549
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dissecting the role of TGF-beta type I receptor/ALK5 in pancreatic ductal adenocarcinoma: Smad activation is crucial for both the tumor suppressive and prometastatic function.
    Schniewind B; Groth S; Sebens Müerköster S; Sipos B; Schäfer H; Kalthoff H; Fändrich F; Ungefroren H
    Oncogene; 2007 Jul; 26(33):4850-62. PubMed ID: 17297450
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Oncogenic Ras blocks transforming growth factor-beta-induced cell-cycle arrest by degradation of p27 through a MEK/Erk/SKP2-dependent pathway.
    Schepers H; Wierenga AT; Eggen BJ; Vellenga E
    Exp Hematol; 2005 Jul; 33(7):747-57. PubMed ID: 15963850
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Overexpression of serine-threonine receptor kinase-associated protein in colorectal cancers.
    Kim CJ; Choi BJ; Song JH; Park YK; Cho YG; Nam SW; Yoo NJ; Lee JY; Park WS
    Pathol Int; 2007 Apr; 57(4):178-82. PubMed ID: 17316412
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The role for transforming growth factor-beta (TGF-beta) in human cancer.
    Gold LI
    Crit Rev Oncog; 1999; 10(4):303-60. PubMed ID: 10654929
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phosphorylation and activation of cell division cycle associated 5 by mitogen-activated protein kinase play a crucial role in human lung carcinogenesis.
    Nguyen MH; Koinuma J; Ueda K; Ito T; Tsuchiya E; Nakamura Y; Daigo Y
    Cancer Res; 2010 Jul; 70(13):5337-47. PubMed ID: 20551060
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SB-431542 and Gleevec inhibit transforming growth factor-beta-induced proliferation of human osteosarcoma cells.
    Matsuyama S; Iwadate M; Kondo M; Saitoh M; Hanyu A; Shimizu K; Aburatani H; Mishima HK; Imamura T; Miyazono K; Miyazawa K
    Cancer Res; 2003 Nov; 63(22):7791-8. PubMed ID: 14633705
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutant p53 attenuates the SMAD-dependent transforming growth factor beta1 (TGF-beta1) signaling pathway by repressing the expression of TGF-beta receptor type II.
    Kalo E; Buganim Y; Shapira KE; Besserglick H; Goldfinger N; Weisz L; Stambolsky P; Henis YI; Rotter V
    Mol Cell Biol; 2007 Dec; 27(23):8228-42. PubMed ID: 17875924
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Smad2 and Smad3 phosphorylated at both linker and COOH-terminal regions transmit malignant TGF-beta signal in later stages of human colorectal cancer.
    Matsuzaki K; Kitano C; Murata M; Sekimoto G; Yoshida K; Uemura Y; Seki T; Taketani S; Fujisawa J; Okazaki K
    Cancer Res; 2009 Jul; 69(13):5321-30. PubMed ID: 19531654
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling.
    Watanabe Y; Itoh S; Goto T; Ohnishi E; Inamitsu M; Itoh F; Satoh K; Wiercinska E; Yang W; Shi L; Tanaka A; Nakano N; Mommaas AM; Shibuya H; Ten Dijke P; Kato M
    Mol Cell; 2010 Jan; 37(1):123-34. PubMed ID: 20129061
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TGF beta-induced focal complex formation in epithelial cells is mediated by activated ERK and JNK MAP kinases and is independent of Smad4.
    Imamichi Y; Waidmann O; Hein R; Eleftheriou P; Giehl K; Menke A
    Biol Chem; 2005 Mar; 386(3):225-36. PubMed ID: 15843168
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.