BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 16778306)

  • 1. Topoisomerase research of kinetoplastid parasite Leishmania, with special reference to development of therapeutics.
    Das BB; Sen N; Dasgupta SB; Ganguly A; Das R; Majumder HK
    Indian J Med Res; 2006 Mar; 123(3):221-32. PubMed ID: 16778306
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Topoisomerases of kinetoplastid parasites as potential chemotherapeutic targets.
    Das A; Dasgupta A; Sengupta T; Majumder HK
    Trends Parasitol; 2004 Aug; 20(8):381-7. PubMed ID: 15246322
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DNA topoisomerases of Leishmania: the potential targets for anti-leishmanial therapy.
    Das BB; Ganguly A; Majumder HK
    Adv Exp Med Biol; 2008; 625():103-15. PubMed ID: 18365662
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Topoisomerases of kinetoplastid parasites: why so fascinating?
    Das BB; Sengupta T; Ganguly A; Majumder HK
    Mol Microbiol; 2006 Nov; 62(4):917-27. PubMed ID: 17042788
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dihydrobetulinic acid induces apoptosis in Leishmania donovani by targeting DNA topoisomerase I and II: implications in antileishmanial therapy.
    Chowdhury AR; Mandal S; Goswami A; Ghosh M; Mandal L; Chakraborty D; Ganguly A; Tripathi G; Mukhopadhyay S; Bandyopadhyay S; Majumder HK
    Mol Med; 2003; 9(1-2):26-36. PubMed ID: 12765337
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Isobenzofuranone derivative JVPH3, an inhibitor of L. donovani topoisomerase II, disrupts mitochondrial architecture in trypanosomatid parasites.
    Chowdhury SR; Godinho JLP; Vinayagam J; Zuma AA; Silva STM; Jaisankar P; Rodrigues JCF; De Souza W; Majumder HK
    Sci Rep; 2018 Aug; 8(1):11940. PubMed ID: 30093616
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reconstitution and functional characterization of the unusual bi-subunit type I DNA topoisomerase from Leishmania donovani.
    Das BB; Sen N; Ganguly A; Majumder HK
    FEBS Lett; 2004 May; 565(1-3):81-8. PubMed ID: 15135057
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA topoisomerases in life and death: implications in kinetoplastid protozoa.
    Chowdhury AR; Majumder HK
    Curr Mol Med; 2004 Sep; 4(6):711-22. PubMed ID: 15357219
    [TBL] [Abstract][Full Text] [Related]  

  • 9. An insight into the mechanism of inhibition of unusual bi-subunit topoisomerase I from Leishmania donovani by 3,3'-di-indolylmethane, a novel DNA topoisomerase I poison with a strong binding affinity to the enzyme.
    Roy A; Das BB; Ganguly A; Bose Dasgupta S; Khalkho NV; Pal C; Dey S; Giri VS; Jaisankar P; Dey S; Majumder HK
    Biochem J; 2008 Jan; 409(2):611-22. PubMed ID: 17922678
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A type 1 DNA topoisomerase from the kinetoplast hemoflagellate Leishmania donovani.
    Chakraborty AK; Gupta A; Majumder HK
    Indian J Biochem Biophys; 1993 Oct; 30(5):257-63. PubMed ID: 8144168
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An insight into the active site of a type I DNA topoisomerase from the kinetoplastid protozoan Leishmania donovani.
    Das A; Mandal C; Dasgupta A; Sengupta T; Majumder HK
    Nucleic Acids Res; 2002 Feb; 30(3):794-802. PubMed ID: 11809893
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A tyrosyl DNA phosphodiesterase 1 from kinetoplastid parasite Leishmania donovani (LdTdp1) capable of removing topo I-DNA covalent complexes.
    Banerjee B; Roy A; Sen N; Majumder HK
    Mol Microbiol; 2010 Oct; 78(1):119-37. PubMed ID: 20659295
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DNA Topoisomerases of Kinetoplastid Parasites: Brief Overview and Recent Perspectives.
    Saha S; Chowdhury SR; Majumder HK
    Curr Issues Mol Biol; 2019; 31():45-62. PubMed ID: 31165719
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The structure of the transition state of the heterodimeric topoisomerase I of Leishmania donovani as a vanadate complex with nicked DNA.
    Davies DR; Mushtaq A; Interthal H; Champoux JJ; Hol WG
    J Mol Biol; 2006 Apr; 357(4):1202-10. PubMed ID: 16487540
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The large subunit of Leishmania topoisomerase I functions as the 'molecular steer' in type IB topoisomerase.
    BoseDasgupta S; Ganguly A; Das BB; Roy A; Khalkho NV; Majumder HK
    Mol Microbiol; 2008 Jan; 67(1):31-46. PubMed ID: 18036140
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Leishmania donovani bisubunit topoisomerase I gene fusion leads to an active enzyme with conserved type IB enzyme function.
    Das BB; Bose Dasgupta S; Ganguly A; Mazumder S; Roy A; Majumder HK
    FEBS J; 2007 Jan; 274(1):150-63. PubMed ID: 17222179
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Expression, purification and characterization of recombinant mitochondrial topoisomerase II of kinetoplastid Crithidia fasciculata in High-five insect cells.
    Wang Y; Tsai YC; Urena-Rivera E; Chen J
    Protein Expr Purif; 2008 Mar; 58(1):122-31. PubMed ID: 18068376
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting atypical trypanosomatid DNA topoisomerase I.
    Balaña-Fouce R; Redondo CM; Pérez-Pertejo Y; Díaz-González R; Reguera RM
    Drug Discov Today; 2006 Aug; 11(15-16):733-40. PubMed ID: 16846801
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antileishmanial activity mediated by apoptosis and structure-based target study of peganine hydrochloride dihydrate: an approach for rational drug design.
    Misra P; Khaliq T; Dixit A; SenGupta S; Samant M; Kumari S; Kumar A; Kushawaha PK; Majumder HK; Saxena AK; Narender T; Dube A
    J Antimicrob Chemother; 2008 Nov; 62(5):998-1002. PubMed ID: 18694906
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural insights on the small subunit of DNA topoisomerase I from the unicellular parasite Leishmania donovani.
    Díaz González R; Pérez Pertejo Y; Redondo CM; Pommier Y; Balaña-Fouce R; Reguera RM
    Biochimie; 2007 Dec; 89(12):1517-27. PubMed ID: 17900785
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.