214 related articles for article (PubMed ID: 16782349)
1. Toward bifunctional antibody catalysis.
Kikuchi K; Hannak RB; Guo MJ; Kirby AJ; Hilvert D
Bioorg Med Chem; 2006 Sep; 14(18):6189-96. PubMed ID: 16782349
[TBL] [Abstract][Full Text] [Related]
2. Large rate accelerations in antibody catalysis by strategic use of haptenic charge.
Thorn SN; Daniels RG; Auditor MT; Hilvert D
Nature; 1995 Jan; 373(6511):228-30. PubMed ID: 7816136
[TBL] [Abstract][Full Text] [Related]
3. Positional ordering of reacting groups contributes significantly to the efficiency of proton transfer at an antibody active site.
Seebeck FP; Hilvert D
J Am Chem Soc; 2005 Feb; 127(4):1307-12. PubMed ID: 15669871
[TBL] [Abstract][Full Text] [Related]
4. Structural basis for antibody catalysis of a disfavored ring closure reaction.
Gruber K; Zhou B; Houk KN; Lerner RA; Shevlin CG; Wilson IA
Biochemistry; 1999 Jun; 38(22):7062-74. PubMed ID: 10353817
[TBL] [Abstract][Full Text] [Related]
5. Improvement in hydrolytic antibody activity by change in haptenic structure from phosphate to phosphonate with retention of a common leaving-group determinant: evidence for the 'flexibility' hypothesis.
Gul S; Sonkaria S; Pinitglang S; Florez-Alvarez J; Hussain S; Thomas EW; Ostler EL; Gallacher G; Resmini M; Brocklehurst K
Biochem J; 2003 Dec; 376(Pt 3):813-21. PubMed ID: 12946271
[TBL] [Abstract][Full Text] [Related]
6. Transition state docking: a probe for noncovalent catalysis in biological systems. Application to antibody-catalyzed ester hydrolysis.
Tantillo DJ; Houk KN
J Comput Chem; 2002 Jan; 23(1):84-95. PubMed ID: 11913392
[TBL] [Abstract][Full Text] [Related]
7. Catalytic antibodies: hapten design strategies and screening methods.
Xu Y; Yamamoto N; Janda KD
Bioorg Med Chem; 2004 Oct; 12(20):5247-68. PubMed ID: 15388154
[TBL] [Abstract][Full Text] [Related]
8. A new strategy for the generation of catalytic antibodies.
Shokat KM; Leumann CJ; Sugasawara R; Schultz PG
Nature; 1989 Mar; 338(6212):269-71. PubMed ID: 2922053
[TBL] [Abstract][Full Text] [Related]
9. New strategies for the design of catalytic antibodies.
Janda KD
Biotechnol Prog; 1990; 6(3):178-81. PubMed ID: 1366610
[TBL] [Abstract][Full Text] [Related]
10. Immunological optimization of a generic hydrophobic pocket for high affinity hapten binding and Diels-Alder activity.
Piatesi A; Hilvert D
Chembiochem; 2004 Apr; 5(4):460-6. PubMed ID: 15185369
[TBL] [Abstract][Full Text] [Related]
11. Squaric monoamide monoester as a new class of reactive immunization hapten for catalytic antibodies.
Xu Y; Yamamoto N; Ruiz DI; Kubitz DS; Janda KD
Bioorg Med Chem Lett; 2005 Oct; 15(19):4304-7. PubMed ID: 16046128
[TBL] [Abstract][Full Text] [Related]
12. Antibody catalysis via strategic use of haptenic charge.
Kikuchi K; Hilvert D
Acta Chem Scand (Cph); 1996 Apr; 50(4):333-6. PubMed ID: 8639376
[TBL] [Abstract][Full Text] [Related]
13. Thermodynamic and structural basis for transition-state stabilization in antibody-catalyzed hydrolysis.
Oda M; Ito N; Tsumuraya T; Suzuki K; Sakakura M; Fujii I
J Mol Biol; 2007 May; 369(1):198-209. PubMed ID: 17428500
[TBL] [Abstract][Full Text] [Related]
14. Structural basis for a disfavored elimination reaction in catalytic antibody 1D4.
Larsen NA; Heine A; Crane L; Cravatt BF; Lerner RA; Wilson IA
J Mol Biol; 2001 Nov; 314(1):93-102. PubMed ID: 11724535
[TBL] [Abstract][Full Text] [Related]
15. Structural origins of efficient proton abstraction from carbon by a catalytic antibody.
Debler EW; Ito S; Seebeck FP; Heine A; Hilvert D; Wilson IA
Proc Natl Acad Sci U S A; 2005 Apr; 102(14):4984-9. PubMed ID: 15788533
[TBL] [Abstract][Full Text] [Related]
16. Catalysis on the coastline: theozyme, molecular dynamics, and free energy perturbation analysis of antibody 21D8 catalysis of the decarboxylation of 5-nitro-3-carboxybenzisoxazole.
Ujaque G; Tantillo DJ; Hu Y; Houk KN; Hotta K; Hilvert D
J Comput Chem; 2003 Jan; 24(1):98-110. PubMed ID: 12483679
[TBL] [Abstract][Full Text] [Related]
17. Directed evolution governed by controlling the molecular recognition between an abzyme and its haptenic transition-state analog.
Takahashi-Ando N; Kakinuma H; Fujii I; Nishi Y
J Immunol Methods; 2004 Nov; 294(1-2):1-14. PubMed ID: 15604011
[TBL] [Abstract][Full Text] [Related]
18. Critical analysis of antibody catalysis.
Hilvert D
Annu Rev Biochem; 2000; 69():751-93. PubMed ID: 10966475
[TBL] [Abstract][Full Text] [Related]
19. A catalytic antibody against a tocopherol cyclase inhibitor.
Manetsch R; Zheng L; Reymond MT; Woggon WD; Reymond JL
Chemistry; 2004 May; 10(10):2487-506. PubMed ID: 15146522
[TBL] [Abstract][Full Text] [Related]
20. Nonspecific medium effects versus specific group positioning in the antibody and albumin catalysis of the base-promoted ring-opening reactions of benzisoxazoles.
Hu Y; Houk KN; Kikuchi K; Hotta K; Hilvert D
J Am Chem Soc; 2004 Jul; 126(26):8197-205. PubMed ID: 15225061
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]