BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

401 related articles for article (PubMed ID: 16785236)

  • 1. Indirubin enhances tumor necrosis factor-induced apoptosis through modulation of nuclear factor-kappa B signaling pathway.
    Sethi G; Ahn KS; Sandur SK; Lin X; Chaturvedi MM; Aggarwal BB
    J Biol Chem; 2006 Aug; 281(33):23425-35. PubMed ID: 16785236
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of a novel blocker of I kappa B alpha kinase that enhances cellular apoptosis and inhibits cellular invasion through suppression of NF-kappa B-regulated gene products.
    Ichikawa H; Takada Y; Murakami A; Aggarwal BB
    J Immunol; 2005 Jun; 174(11):7383-92. PubMed ID: 15905586
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Fisetin, an inhibitor of cyclin-dependent kinase 6, down-regulates nuclear factor-kappaB-regulated cell proliferation, antiapoptotic and metastatic gene products through the suppression of TAK-1 and receptor-interacting protein-regulated IkappaBalpha kinase activation.
    Sung B; Pandey MK; Aggarwal BB
    Mol Pharmacol; 2007 Jun; 71(6):1703-14. PubMed ID: 17387141
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Butein, a tetrahydroxychalcone, inhibits nuclear factor (NF)-kappaB and NF-kappaB-regulated gene expression through direct inhibition of IkappaBalpha kinase beta on cysteine 179 residue.
    Pandey MK; Sandur SK; Sung B; Sethi G; Kunnumakkara AB; Aggarwal BB
    J Biol Chem; 2007 Jun; 282(24):17340-50. PubMed ID: 17439942
    [TBL] [Abstract][Full Text] [Related]  

  • 5. N-(4-hydroxyphenyl)retinamide inhibits invasion, suppresses osteoclastogenesis, and potentiates apoptosis through down-regulation of I(kappa)B(alpha) kinase and nuclear factor-kappaB-regulated gene products.
    Shishodia S; Gutierrez AM; Lotan R; Aggarwal BB
    Cancer Res; 2005 Oct; 65(20):9555-65. PubMed ID: 16230421
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Diosgenin inhibits osteoclastogenesis, invasion, and proliferation through the downregulation of Akt, I kappa B kinase activation and NF-kappa B-regulated gene expression.
    Shishodia S; Aggarwal BB
    Oncogene; 2006 Mar; 25(10):1463-73. PubMed ID: 16331273
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting nuclear factor-kappa B activation pathway by thymoquinone: role in suppression of antiapoptotic gene products and enhancement of apoptosis.
    Sethi G; Ahn KS; Aggarwal BB
    Mol Cancer Res; 2008 Jun; 6(6):1059-70. PubMed ID: 18567808
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-kappaB signaling pathway.
    Pandey MK; Sung B; Ahn KS; Kunnumakkara AB; Chaturvedi MM; Aggarwal BB
    Blood; 2007 Nov; 110(10):3517-25. PubMed ID: 17673602
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Berberine modifies cysteine 179 of IkappaBalpha kinase, suppresses nuclear factor-kappaB-regulated antiapoptotic gene products, and potentiates apoptosis.
    Pandey MK; Sung B; Kunnumakkara AB; Sethi G; Chaturvedi MM; Aggarwal BB
    Cancer Res; 2008 Jul; 68(13):5370-9. PubMed ID: 18593939
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pinitol targets nuclear factor-kappaB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis.
    Sethi G; Ahn KS; Sung B; Aggarwal BB
    Mol Cancer Ther; 2008 Jun; 7(6):1604-14. PubMed ID: 18566231
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Magnolol suppresses NF-kappaB activation and NF-kappaB regulated gene expression through inhibition of IkappaB kinase activation.
    Tse AK; Wan CK; Zhu GY; Shen XL; Cheung HY; Yang M; Fong WF
    Mol Immunol; 2007 Apr; 44(10):2647-58. PubMed ID: 17240450
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Honokiol potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through modulation of nuclear factor-kappaB activation pathway.
    Ahn KS; Sethi G; Shishodia S; Sung B; Arbiser JL; Aggarwal BB
    Mol Cancer Res; 2006 Sep; 4(9):621-33. PubMed ID: 16966432
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Honokiol inhibits TNF-alpha-stimulated NF-kappaB activation and NF-kappaB-regulated gene expression through suppression of IKK activation.
    Tse AK; Wan CK; Shen XL; Yang M; Fong WF
    Biochem Pharmacol; 2005 Nov; 70(10):1443-57. PubMed ID: 16181613
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Gamma-tocotrienol inhibits nuclear factor-kappaB signaling pathway through inhibition of receptor-interacting protein and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis.
    Ahn KS; Sethi G; Krishnan K; Aggarwal BB
    J Biol Chem; 2007 Jan; 282(1):809-20. PubMed ID: 17114179
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells.
    Shishodia S; Sethi G; Konopleva M; Andreeff M; Aggarwal BB
    Clin Cancer Res; 2006 Mar; 12(6):1828-38. PubMed ID: 16551868
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Zerumbone abolishes NF-kappaB and IkappaBalpha kinase activation leading to suppression of antiapoptotic and metastatic gene expression, upregulation of apoptosis, and downregulation of invasion.
    Takada Y; Murakami A; Aggarwal BB
    Oncogene; 2005 Oct; 24(46):6957-69. PubMed ID: 16007145
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IkappaBalpha kinase and Akt activation.
    Aggarwal S; Ichikawa H; Takada Y; Sandur SK; Shishodia S; Aggarwal BB
    Mol Pharmacol; 2006 Jan; 69(1):195-206. PubMed ID: 16219905
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Protein farnesyltransferase inhibitor (SCH 66336) abolishes NF-kappaB activation induced by various carcinogens and inflammatory stimuli leading to suppression of NF-kappaB-regulated gene expression and up-regulation of apoptosis.
    Takada Y; Khuri FR; Aggarwal BB
    J Biol Chem; 2004 Jun; 279(25):26287-99. PubMed ID: 15090542
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evodiamine abolishes constitutive and inducible NF-kappaB activation by inhibiting IkappaBalpha kinase activation, thereby suppressing NF-kappaB-regulated antiapoptotic and metastatic gene expression, up-regulating apoptosis, and inhibiting invasion.
    Takada Y; Kobayashi Y; Aggarwal BB
    J Biol Chem; 2005 Apr; 280(17):17203-12. PubMed ID: 15710601
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) suppresses NF-kappaB activation and NF-kappaB-regulated gene products through modulation of p65 and IkappaBalpha kinase activation, leading to potentiation of apoptosis induced by cytokine and chemotherapeutic agents.
    Sandur SK; Ichikawa H; Sethi G; Ahn KS; Aggarwal BB
    J Biol Chem; 2006 Jun; 281(25):17023-17033. PubMed ID: 16624823
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.