BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

246 related articles for article (PubMed ID: 16785528)

  • 1. Analysis of TLR4 polymorphic variants: new insights into TLR4/MD-2/CD14 stoichiometry, structure, and signaling.
    Rallabhandi P; Bell J; Boukhvalova MS; Medvedev A; Lorenz E; Arditi M; Hemming VG; Blanco JC; Segal DM; Vogel SN
    J Immunol; 2006 Jul; 177(1):322-32. PubMed ID: 16785528
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Respiratory syncytial virus fusion protein-induced toll-like receptor 4 (TLR4) signaling is inhibited by the TLR4 antagonists Rhodobacter sphaeroides lipopolysaccharide and eritoran (E5564) and requires direct interaction with MD-2.
    Rallabhandi P; Phillips RL; Boukhvalova MS; Pletneva LM; Shirey KA; Gioannini TL; Weiss JP; Chow JC; Hawkins LD; Vogel SN; Blanco JC
    mBio; 2012; 3(4):. PubMed ID: 22872782
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interaction of soluble form of recombinant extracellular TLR4 domain with MD-2 enables lipopolysaccharide binding and attenuates TLR4-mediated signaling.
    Hyakushima N; Mitsuzawa H; Nishitani C; Sano H; Kuronuma K; Konishi M; Himi T; Miyake K; Kuroki Y
    J Immunol; 2004 Dec; 173(11):6949-54. PubMed ID: 15557191
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Evidence of a specific interaction between new synthetic antisepsis agents and CD14.
    Piazza M; Yu L; Teghanemt A; Gioannini T; Weiss J; Peri F
    Biochemistry; 2009 Dec; 48(51):12337-44. PubMed ID: 19928913
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression of functional D299G.T399I polymorphic variant of TLR4 depends more on coexpression of MD-2 than does wild-type TLR4.
    Prohinar P; Rallabhandi P; Weiss JP; Gioannini TL
    J Immunol; 2010 Apr; 184(8):4362-7. PubMed ID: 20212095
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Host species-specific usage of the TLR4-LPS receptor complex.
    Lizundia R; Sauter KS; Taylor G; Werling D
    Innate Immun; 2008 Aug; 14(4):223-31. PubMed ID: 18669608
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of human TLR4 in respiratory syncytial virus-induced NF-κB activation, viral entry and replication.
    Marr N; Turvey SE
    Innate Immun; 2012 Dec; 18(6):856-65. PubMed ID: 22535679
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Functional activity of MD-2 polymorphic variant is significantly different in soluble and TLR4-bound forms: decreased endotoxin binding by G56R MD-2 and its rescue by TLR4 ectodomain.
    Vasl J; Prohinar P; Gioannini TL; Weiss JP; Jerala R
    J Immunol; 2008 May; 180(9):6107-15. PubMed ID: 18424732
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Exogenous MD-2 confers lipopolysaccharide responsiveness to human corneal epithelial cells with intracellular expression of TLR4 and CD14.
    Lang LL; Wang L; Liu L
    Inflammation; 2011 Oct; 34(5):371-8. PubMed ID: 20700758
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel roles in human MD-2 of phenylalanines 121 and 126 and tyrosine 131 in activation of Toll-like receptor 4 by endotoxin.
    Teghanemt A; Re F; Prohinar P; Widstrom R; Gioannini TL; Weiss JP
    J Biol Chem; 2008 Jan; 283(3):1257-1266. PubMed ID: 17977838
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Unique properties of the chicken TLR4/MD-2 complex: selective lipopolysaccharide activation of the MyD88-dependent pathway.
    Keestra AM; van Putten JP
    J Immunol; 2008 Sep; 181(6):4354-62. PubMed ID: 18768894
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of mouse MD-2 residues important for forming the cell surface TLR4-MD-2 complex recognized by anti-TLR4-MD-2 antibodies, and for conferring LPS and taxol responsiveness on mouse TLR4 by alanine-scanning mutagenesis.
    Kawasaki K; Nogawa H; Nishijima M
    J Immunol; 2003 Jan; 170(1):413-20. PubMed ID: 12496426
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Toll-like receptor 4 polymorphism Asp299Gly but not Thr399Ile influences TLR4 signaling and function.
    Long H; O'Connor BP; Zemans RL; Zhou X; Yang IV; Schwartz DA
    PLoS One; 2014; 9(4):e93550. PubMed ID: 24695807
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sialyl residues modulate LPS-mediated signaling through the Toll-like receptor 4 complex.
    Feng C; Stamatos NM; Dragan AI; Medvedev A; Whitford M; Zhang L; Song C; Rallabhandi P; Cole L; Nhu QM; Vogel SN; Geddes CD; Cross AS
    PLoS One; 2012; 7(4):e32359. PubMed ID: 22496731
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Induction of tolerance to lipopolysaccharide and mycobacterial components in Chinese hamster ovary/CD14 cells is not affected by overexpression of Toll-like receptors 2 or 4.
    Medvedev AE; Henneke P; Schromm A; Lien E; Ingalls R; Fenton MJ; Golenbock DT; Vogel SN
    J Immunol; 2001 Aug; 167(4):2257-67. PubMed ID: 11490013
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex.
    Okamoto N; Mizote K; Honda H; Saeki A; Watanabe Y; Yamaguchi-Miyamoto T; Fukui R; Tanimura N; Motoi Y; Akashi-Takamura S; Kato T; Fujishita S; Kimura T; Ohto U; Shimizu T; Hirokawa T; Miyake K; Fukase K; Fujimoto Y; Nagai Y; Takatsu K
    J Biol Chem; 2017 Sep; 292(37):15378-15394. PubMed ID: 28754693
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human TLR4 polymorphism D299G/T399I alters TLR4/MD-2 conformation and response to a weak ligand monophosphoryl lipid A.
    Yamakawa N; Ohto U; Akashi-Takamura S; Takahashi K; Saitoh S; Tanimura N; Suganami T; Ogawa Y; Shibata T; Shimizu T; Miyake K
    Int Immunol; 2013 Jan; 25(1):45-52. PubMed ID: 22962435
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential activation of human TLR4 by Escherichia coli and Shigella flexneri 2a lipopolysaccharide: combined effects of lipid A acylation state and TLR4 polymorphisms on signaling.
    Rallabhandi P; Awomoyi A; Thomas KE; Phalipon A; Fujimoto Y; Fukase K; Kusumoto S; Qureshi N; Sztein MB; Vogel SN
    J Immunol; 2008 Jan; 180(2):1139-47. PubMed ID: 18178854
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural insights into pharmacophore-assisted in silico identification of protein-protein interaction inhibitors for inhibition of human toll-like receptor 4 - myeloid differentiation factor-2 (hTLR4-MD-2) complex.
    Mishra V; Pathak C
    J Biomol Struct Dyn; 2019 May; 37(8):1968-1991. PubMed ID: 29842849
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dynamic lipopolysaccharide transfer cascade to TLR4/MD2 complex via LBP and CD14.
    Kim SJ; Kim HM
    BMB Rep; 2017 Feb; 50(2):55-57. PubMed ID: 28115037
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.