251 related articles for article (PubMed ID: 16787156)
1. Utility of mass spectrometry for in-vitro ADME assays.
Chu I; Nomeir AA
Curr Drug Metab; 2006 Jun; 7(5):467-77. PubMed ID: 16787156
[TBL] [Abstract][Full Text] [Related]
2. Strategies to in vitro assessment of major human CYP enzyme activities by using liquid chromatography tandem mass spectrometry.
Lahoz A; Donato MT; Castell JV; Gómez-Lechón MJ
Curr Drug Metab; 2008 Jan; 9(1):12-9. PubMed ID: 18220567
[TBL] [Abstract][Full Text] [Related]
3. Validation of higher-throughput high-performance liquid chromatography/atmospheric pressure chemical ionization tandem mass spectrometry assays to conduct cytochrome P450s CYP2D6 and CYP3A4 enzyme inhibition studies in human liver microsomes.
Chu I; Favreau L; Soares T; Lin Cc; Nomeir AA
Rapid Commun Mass Spectrom; 2000; 14(4):207-14. PubMed ID: 10669878
[TBL] [Abstract][Full Text] [Related]
4. Higher-throughput screening for Caco-2 permeability utilizing a multiple sprayer liquid chromatography/tandem mass spectrometry system.
Fung EN; Chu I; Li C; Liu T; Soares A; Morrison R; Nomeir AA
Rapid Commun Mass Spectrom; 2003; 17(18):2147-52. PubMed ID: 12955746
[TBL] [Abstract][Full Text] [Related]
5. Introduction to in vitro estimation of metabolic stability and drug interactions of new chemical entities in drug discovery and development.
Baranczewski P; Stańczak A; Sundberg K; Svensson R; Wallin A; Jansson J; Garberg P; Postlind H
Pharmacol Rep; 2006; 58(4):453-72. PubMed ID: 16963792
[TBL] [Abstract][Full Text] [Related]
6. Drug metabolism and pharmacokinetics in drug discovery.
Roberts SA
Curr Opin Drug Discov Devel; 2003 Jan; 6(1):66-80. PubMed ID: 12613278
[TBL] [Abstract][Full Text] [Related]
7. High-throughput screening approaches for investigating drug metabolism and pharmacokinetics.
Roberts SA
Xenobiotica; 2001; 31(8-9):557-89. PubMed ID: 11569526
[TBL] [Abstract][Full Text] [Related]
8. Metabolite characterization in drug discovery utilizing robotic liquid-handling, quadruple time-of-flight mass spectrometry and in-silico prediction.
Nassar AE; Adams PE
Curr Drug Metab; 2003 Aug; 4(4):259-71. PubMed ID: 12871044
[TBL] [Abstract][Full Text] [Related]
9. Metabolism profiling, and cytochrome P450 inhibition & induction in drug discovery.
Yan Z; Caldwell GW
Curr Top Med Chem; 2001 Nov; 1(5):403-25. PubMed ID: 11899105
[TBL] [Abstract][Full Text] [Related]
10. Automated screening with confirmation of mechanism-based inactivation of CYP3A4, CYP2C9, CYP2C19, CYP2D6, and CYP1A2 in pooled human liver microsomes.
Lim HK; Duczak N; Brougham L; Elliot M; Patel K; Chan K
Drug Metab Dispos; 2005 Aug; 33(8):1211-9. PubMed ID: 15860655
[TBL] [Abstract][Full Text] [Related]
11. The role of hyphenated chromatography-mass spectrometry techniques in exploratory drug metabolism and pharmacokinetics.
Hsieh Y; Korfmacher W
Curr Pharm Des; 2009; 15(19):2251-61. PubMed ID: 19601826
[TBL] [Abstract][Full Text] [Related]
12. Increasing speed and throughput when using HPLC-MS/MS systems for drug metabolism and pharmacokinetic screening.
Hsieh Y; Korfmacher WA
Curr Drug Metab; 2006 Jun; 7(5):479-89. PubMed ID: 16787157
[TBL] [Abstract][Full Text] [Related]
13. In vitro ADME profiling using high-throughput rapidfire mass spectrometry: cytochrome p450 inhibition and metabolic stability assays.
Wu X; Wang J; Tan L; Bui J; Gjerstad E; McMillan K; Zhang W
J Biomol Screen; 2012 Jul; 17(6):761-72. PubMed ID: 22460176
[TBL] [Abstract][Full Text] [Related]
14. A review of LC-MS techniques and high-throughput approaches used to investigate drug metabolism by cytochrome P450s.
Youdim KA; Saunders KC
J Chromatogr B Analyt Technol Biomed Life Sci; 2010 May; 878(17-18):1326-36. PubMed ID: 20207203
[TBL] [Abstract][Full Text] [Related]
15. In vitro LC-MS cocktail assays to simultaneously determine human cytochrome P450 activities.
Dixit V; Hariparsad N; Desai P; Unadkat JD
Biopharm Drug Dispos; 2007 Jul; 28(5):257-62. PubMed ID: 17443647
[TBL] [Abstract][Full Text] [Related]
16. Automatic mass spectrometry method development for drug discovery: application in metabolic stability assays.
Chovan LE; Black-Schaefer C; Dandliker PJ; Lau YY
Rapid Commun Mass Spectrom; 2004; 18(24):3105-12. PubMed ID: 15565734
[TBL] [Abstract][Full Text] [Related]
17. HPLC-MS/MS in drug metabolism and pharmacokinetic screening.
Hsieh Y
Expert Opin Drug Metab Toxicol; 2008 Jan; 4(1):93-101. PubMed ID: 18370861
[TBL] [Abstract][Full Text] [Related]
18. The Application of Mass Spectrometry in Drug Metabolism and Pharmacokinetics.
Lee JY; Kim SK; Lee K; Oh SJ
Adv Exp Med Biol; 2021; 1310():533-550. PubMed ID: 33834449
[TBL] [Abstract][Full Text] [Related]
19. Introduction to early in vitro identification of metabolites of new chemical entities in drug discovery and development.
Baranczewski P; Stańczak A; Kautiainen A; Sandin P; Edlund PO
Pharmacol Rep; 2006; 58(3):341-52. PubMed ID: 16845208
[TBL] [Abstract][Full Text] [Related]
20. EUFEPS conference on drug transporters at Copenhagen: integrative approaches in ADME research.
Meijer DK; Lennernäs H
Eur J Pharm Sci; 2005 Sep; 26(1):130-43. PubMed ID: 16161216
[No Abstract] [Full Text] [Related]
[Next] [New Search]
