BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

110 related articles for article (PubMed ID: 16787777)

  • 1. Extended substrate recognition in caspase-3 revealed by high resolution X-ray structure analysis.
    Ganesan R; Mittl PR; Jelakovic S; Grütter MG
    J Mol Biol; 2006 Jun; 359(5):1378-88. PubMed ID: 16787777
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural and kinetic analysis of caspase-3 reveals role for s5 binding site in substrate recognition.
    Fang B; Boross PI; Tozser J; Weber IT
    J Mol Biol; 2006 Jul; 360(3):654-66. PubMed ID: 16781734
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Exploring the S4 and S1 prime subsite specificities in caspase-3 with aza-peptide epoxide inhibitors.
    Ganesan R; Jelakovic S; Campbell AJ; Li ZZ; Asgian JL; Powers JC; Grütter MG
    Biochemistry; 2006 Aug; 45(30):9059-67. PubMed ID: 16866351
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Caspase-8 specificity probed at subsite S(4): crystal structure of the caspase-8-Z-DEVD-cho complex.
    Blanchard H; Donepudi M; Tschopp M; Kodandapani L; Wu JC; Grütter MG
    J Mol Biol; 2000 Sep; 302(1):9-16. PubMed ID: 10964557
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Conformational restrictions in the active site of unliganded human caspase-3.
    Ni CZ; Li C; Wu JC; Spada AP; Ely KR
    J Mol Recognit; 2003; 16(3):121-4. PubMed ID: 12833566
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Caspase-3 binds diverse P4 residues in peptides as revealed by crystallography and structural modeling.
    Fang B; Fu G; Agniswamy J; Harrison RW; Weber IT
    Apoptosis; 2009 May; 14(5):741-52. PubMed ID: 19283487
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Homology modeling of nematode Caenorhabditis elegans CED3 protein-inhibitor complex.
    Azim MK; Grossmann JG; Zaidi ZH
    Biochem Biophys Res Commun; 2001 Feb; 281(1):115-21. PubMed ID: 11178968
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The 2.0 A crystal structure and substrate specificity of the KDEL-tailed cysteine endopeptidase functioning in programmed cell death of Ricinus communis endosperm.
    Than ME; Helm M; Simpson DJ; Lottspeich F; Huber R; Gietl C
    J Mol Biol; 2004 Mar; 336(5):1103-16. PubMed ID: 15037072
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human intestinal maltase-glucoamylase: crystal structure of the N-terminal catalytic subunit and basis of inhibition and substrate specificity.
    Sim L; Quezada-Calvillo R; Sterchi EE; Nichols BL; Rose DR
    J Mol Biol; 2008 Jan; 375(3):782-92. PubMed ID: 18036614
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel inhibitor for prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis and details of substrate-recognition mechanism.
    Xu Y; Nakajima Y; Ito K; Zheng H; Oyama H; Heiser U; Hoffmann T; Gärtner UT; Demuth HU; Yoshimoto T
    J Mol Biol; 2008 Jan; 375(3):708-19. PubMed ID: 18042490
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis.
    Agniswamy J; Fang B; Weber IT
    FEBS J; 2007 Sep; 274(18):4752-65. PubMed ID: 17697120
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis, and evaluation of aza-peptide Michael acceptors as selective and potent inhibitors of caspases-2, -3, -6, -7, -8, -9, and -10.
    Ekici OD; Li ZZ; Campbell AJ; James KE; Asgian JL; Mikolajczyk J; Salvesen GS; Ganesan R; Jelakovic S; Grütter MG; Powers JC
    J Med Chem; 2006 Sep; 49(19):5728-49. PubMed ID: 16970398
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Covalent inhibition revealed by the crystal structure of the caspase-8/p35 complex.
    Xu G; Cirilli M; Huang Y; Rich RL; Myszka DG; Wu H
    Nature; 2001 Mar; 410(6827):494-7. PubMed ID: 11260720
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Understanding the structural basis for substrate and inhibitor recognition in eukaryotic GH11 xylanases.
    Vardakou M; Dumon C; Murray JW; Christakopoulos P; Weiner DP; Juge N; Lewis RJ; Gilbert HJ; Flint JE
    J Mol Biol; 2008 Feb; 375(5):1293-305. PubMed ID: 18078955
    [TBL] [Abstract][Full Text] [Related]  

  • 15. X-ray structure of HIV-1 protease in situ product complex.
    Bihani S; Das A; Prashar V; Ferrer JL; Hosur MV
    Proteins; 2009 Feb; 74(3):594-602. PubMed ID: 18704947
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Reducing the peptidyl features of caspase-3 inhibitors: a structural analysis.
    Becker JW; Rotonda J; Soisson SM; Aspiotis R; Bayly C; Francoeur S; Gallant M; Garcia-Calvo M; Giroux A; Grimm E; Han Y; McKay D; Nicholson DW; Peterson E; Renaud J; Roy S; Thornberry N; Zamboni R
    J Med Chem; 2004 May; 47(10):2466-74. PubMed ID: 15115390
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enzyme:substrate hydrogen bond shortening during the acylation phase of serine protease catalysis.
    Fodor K; Harmat V; Neutze R; Szilágyi L; Gráf L; Katona G
    Biochemistry; 2006 Feb; 45(7):2114-21. PubMed ID: 16475800
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phage display and crystallographic analysis reveals potential substrate/binding site interactions in the protein secretion chaperone CsaA from Agrobacterium tumefaciens.
    Feldman AR; Shapova YA; Wu SS; Oliver DC; Heller M; McIntosh LP; Scott JK; Paetzel M
    J Mol Biol; 2008 Jun; 379(3):457-70. PubMed ID: 18462752
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The X-ray structure of N-methyltryptophan oxidase reveals the structural determinants of substrate specificity.
    Ilari A; Bonamore A; Franceschini S; Fiorillo A; Boffi A; Colotti G
    Proteins; 2008 Jun; 71(4):2065-75. PubMed ID: 18186483
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Trapping of an acyl-enzyme intermediate in a penicillin-binding protein (PBP)-catalyzed reaction.
    Macheboeuf P; Lemaire D; Teller N; Martins Ados S; Luxen A; Dideberg O; Jamin M; Dessen A
    J Mol Biol; 2008 Feb; 376(2):405-13. PubMed ID: 18155726
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.