128 related articles for article (PubMed ID: 16798616)
1. The effect of the single substitution of arginine within the RGD tripeptide motif of a modified neurotoxin dendroaspin on its activity of platelet aggregation and cell adhesion.
Lu X; Davies J; Lu D; Xia M; Wattam B; Shang D; Sun Y; Scully M; Kakkar V
Cell Commun Adhes; 2006; 13(3):171-83. PubMed ID: 16798616
[TBL] [Abstract][Full Text] [Related]
2. Arg-Tyr-Asp (RYD) and Arg-Cys-Asp (RCD) motifs in dendroaspin promote selective inhibition of beta1 and beta3 integrins.
Wattam B; Shang D; Rahman S; Egglezou S; Scully M; Kakkar V; Lu X
Biochem J; 2001 May; 356(Pt 1):11-7. PubMed ID: 11336631
[TBL] [Abstract][Full Text] [Related]
3. The integrin alpha IIb beta 3 contains distinct and interacting binding sites for snake-venom RGD (Arg-Gly-Asp) proteins. Evidence that the receptor-binding characteristics of snake-venom RGD proteins are related to the amino acid environment flanking the sequence RGD.
Rahman S; Lu X; Kakkar VV; Authi KS
Biochem J; 1995 Nov; 312 ( Pt 1)(Pt 1):223-32. PubMed ID: 7492316
[TBL] [Abstract][Full Text] [Related]
4. Preferential antagonism of the interactions of the integrin alpha IIb beta 3 with immobilized glycoprotein ligands by snake-venom RGD (Arg-Gly-Asp) proteins. Evidence supporting a functional role for the amino acid residues flanking the tripeptide RGD in determining the inhibitory properties of snake-venom RGD proteins.
Lu X; Williams JA; Deadman JJ; Salmon GP; Kakkar VV; Wilkinson JM; Baruch D; Authi KS; Rahman S
Biochem J; 1994 Dec; 304 ( Pt 3)(Pt 3):929-36. PubMed ID: 7529494
[TBL] [Abstract][Full Text] [Related]
5. Evaluation of the role of proline residues flanking the RGD motif of dendroaspin, an inhibitior of platelet aggregation and cell adhesion.
Lu X; Sun Y; Shang D; Wattam B; Egglezou S; Hughes T; Hyde E; Scully M; Kakkar V
Biochem J; 2001 May; 355(Pt 3):633-8. PubMed ID: 11311124
[TBL] [Abstract][Full Text] [Related]
6. Differential recognition of snake venom proteins expressing specific Arg-Gly-Asp (RGD) sequence motifs by wild-type and variant integrin alphaIIbbeta3: further evidence for distinct sites of RGD ligand recognition exhibiting negative allostery.
Rahman S; Flynn G; Aitken A; Patel Y; Hussain F; Lu X; Loftus JC; French D; Wijelath E; Strand K; Savidge GF
Biochem J; 2000 Feb; 345 Pt 3(Pt 3):701-9. PubMed ID: 10642531
[TBL] [Abstract][Full Text] [Related]
7. Modulation of RGD sequence motifs regulates disintegrin recognition of alphaIIb beta3 and alpha5 beta1 integrin complexes. Replacement of elegantin alanine-50 with proline, N-terminal to the RGD sequence, diminishes recognition of the alpha5 beta1 complex with restoration induced by Mn2+ cation.
Rahman S; Aitken A; Flynn G; Formstone C; Savidge GF
Biochem J; 1998 Oct; 335 ( Pt 2)(Pt 2):247-57. PubMed ID: 9761721
[TBL] [Abstract][Full Text] [Related]
8. Dynamics and functional differences between dendroaspin and rhodostomin: insights into protein scaffolds in integrin recognition.
Cheng CH; Chen YC; Shiu JH; Chang YT; Chang YS; Huang CH; Chen CY; Chuang WJ
Protein Sci; 2012 Dec; 21(12):1872-84. PubMed ID: 23033223
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of platelet function with synthetic peptides designed to be high-affinity antagonists of fibrinogen binding to platelets.
Ruggeri ZM; Houghten RA; Russell SR; Zimmerman TS
Proc Natl Acad Sci U S A; 1986 Aug; 83(15):5708-12. PubMed ID: 3016716
[TBL] [Abstract][Full Text] [Related]
10. Three-dimensional structure of the RGD-containing neurotoxin homologue dendroaspin.
Sutcliffe MJ; Jaseja M; Hyde EI; Lu X; Williams JA
Nat Struct Biol; 1994 Nov; 1(11):802-7. PubMed ID: 7634091
[TBL] [Abstract][Full Text] [Related]
11. Synthetic RGD peptides derived from the adhesive domains of snake-venom proteins: evaluation as inhibitors of platelet aggregation.
Lu X; Deadman JJ; Williams JA; Kakkar VV; Rahman S
Biochem J; 1993 Nov; 296 ( Pt 1)(Pt 1):21-4. PubMed ID: 8250845
[TBL] [Abstract][Full Text] [Related]
12. Substitutions of proline 42 to alanine and methionine 46 to asparagine around the RGD domain of the neurotoxin dendroaspin alter its preferential antagonism to that resembling the disintegrin elegantin.
Lu X; Rahman S; Kakkar VV; Authi KS
J Biol Chem; 1996 Jan; 271(1):289-94. PubMed ID: 8550575
[TBL] [Abstract][Full Text] [Related]
13. Ussuristatin 2, a novel KGD-bearing disintegrin from Agkistrodon ussuriensis venom.
Oshikawa K; Terada S
J Biochem; 1999 Jan; 125(1):31-5. PubMed ID: 9880793
[TBL] [Abstract][Full Text] [Related]
14. Integrin binding characteristics of the disintegrin-like domain of ADAM-15.
Lu D; Chung KF; Xia M; Lu X; Scully M; Kakkar V
Thromb Haemost; 2006 Nov; 96(5):642-51. PubMed ID: 17080222
[TBL] [Abstract][Full Text] [Related]
15. 1H-NMR assignments and secondary structure of dendroaspin, an RGD-containing glycoprotein IIb-IIIa (alpha IIb-beta 3) antagonist with a neurotoxin fold.
Jaseja M; Lu X; Williams JA; Sutcliffe MJ; Kakkar VV; Parslow RA; Hyde EI
Eur J Biochem; 1994 Dec; 226(3):861-8. PubMed ID: 7813476
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of integrin-mediated platelet aggregation, fibrinogen-binding, and interactions with extracellular matrix by nonpeptidic mimetics of Arg-Gly-Asp.
Varon D; Lider O; Dardik R; Shenkman B; Alon R; Hershkoviz R; Kapustina G; Savion N; Martinowitz U; Greenspoon N
Thromb Haemost; 1993 Dec; 70(6):1030-6. PubMed ID: 8165596
[TBL] [Abstract][Full Text] [Related]
17. Solution structure of gamma-bungarotoxin: the functional significance of amino acid residues flanking the RGD motif in integrin binding.
Shiu JH; Chen CY; Chang LS; Chen YC; Chen YC; Lo YH; Liu YC; Chuang WJ
Proteins; 2004 Dec; 57(4):839-49. PubMed ID: 15390258
[TBL] [Abstract][Full Text] [Related]
18. Design of potent and specific integrin antagonists. Peptide antagonists with high specificity for glycoprotein IIb-IIIa.
Scarborough RM; Naughton MA; Teng W; Rose JW; Phillips DR; Nannizzi L; Arfsten A; Campbell AM; Charo IF
J Biol Chem; 1993 Jan; 268(2):1066-73. PubMed ID: 8419315
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of platelet aggregation by grafting RGD and KGD sequences on the structural scaffold of small disulfide-rich proteins.
Reiss S; Sieber M; Oberle V; Wentzel A; Spangenberg P; Claus R; Kolmar H; Lösche W
Platelets; 2006 May; 17(3):153-7. PubMed ID: 16702041
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of cell adhesion by antibodies to Arg-Gly-Asp (RGD) in normal immunoglobulin for therapeutic use (intravenous immunoglobulin, IVIg).
Vassilev TL; Kazatchkine MD; Duong Van Huyen JP; Mekrache M; Bonnin E; Mani JC; Lecroubier C; Korinth D; Baruch D; Schriever F; Kaveri SV
Blood; 1999 Jun; 93(11):3624-31. PubMed ID: 10339467
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]