These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

488 related articles for article (PubMed ID: 16804197)

  • 1. Islet amyloid polypeptide (IAPP) transgenic rodents as models for type 2 diabetes.
    Matveyenko AV; Butler PC
    ILAR J; 2006; 47(3):225-33. PubMed ID: 16804197
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Toxic human islet amyloid polypeptide (h-IAPP) oligomers are intracellular, and vaccination to induce anti-toxic oligomer antibodies does not prevent h-IAPP-induced beta-cell apoptosis in h-IAPP transgenic mice.
    Lin CY; Gurlo T; Kayed R; Butler AE; Haataja L; Glabe CG; Butler PC
    Diabetes; 2007 May; 56(5):1324-32. PubMed ID: 17353506
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Diabetes due to a progressive defect in beta-cell mass in rats transgenic for human islet amyloid polypeptide (HIP Rat): a new model for type 2 diabetes.
    Butler AE; Jang J; Gurlo T; Carty MD; Soeller WC; Butler PC
    Diabetes; 2004 Jun; 53(6):1509-16. PubMed ID: 15161755
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide.
    Janson J; Soeller WC; Roche PC; Nelson RT; Torchia AJ; Kreutter DK; Butler PC
    Proc Natl Acad Sci U S A; 1996 Jul; 93(14):7283-8. PubMed ID: 8692984
    [TBL] [Abstract][Full Text] [Related]  

  • 5. β-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency.
    Costes S; Huang CJ; Gurlo T; Daval M; Matveyenko AV; Rizza RA; Butler AE; Butler PC
    Diabetes; 2011 Jan; 60(1):227-38. PubMed ID: 20980462
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Autophagy defends pancreatic β cells from human islet amyloid polypeptide-induced toxicity.
    Rivera JF; Costes S; Gurlo T; Glabe CG; Butler PC
    J Clin Invest; 2014 Aug; 124(8):3489-500. PubMed ID: 25036708
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Intravenous immunoglobulin improves glucose control and β-cell function in human IAPP transgenic mice by attenuating islet inflammation and reducing IAPP oligomers.
    Zhang Y; Yu XL; Zhu J; Liu SY; Liu XM; Dong QX; Chai JQ; Liu RT
    Int Immunopharmacol; 2018 Jan; 54():145-152. PubMed ID: 29145032
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Increased beta-cell apoptosis prevents adaptive increase in beta-cell mass in mouse model of type 2 diabetes: evidence for role of islet amyloid formation rather than direct action of amyloid.
    Butler AE; Janson J; Soeller WC; Butler PC
    Diabetes; 2003 Sep; 52(9):2304-14. PubMed ID: 12941770
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Intracellular amyloid-like deposits contain unprocessed pro-islet amyloid polypeptide (proIAPP) in beta cells of transgenic mice overexpressing the gene for human IAPP and transplanted human islets.
    Paulsson JF; Andersson A; Westermark P; Westermark GT
    Diabetologia; 2006 Jun; 49(6):1237-46. PubMed ID: 16570161
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dysregulation of cholesterol homeostasis is an early signal of β-cell proteotoxicity characteristic of type 2 diabetes.
    Gurlo T; Liu R; Wang Z; Hoang J; Ryazantsev S; Daval M; Butler AE; Yang X; Blencowe M; Butler PC
    Physiol Genomics; 2024 Sep; 56(9):621-633. PubMed ID: 38949617
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Exendin-4 increases islet amyloid deposition but offsets the resultant beta cell toxicity in human islet amyloid polypeptide transgenic mouse islets.
    Aston-Mourney K; Hull RL; Zraika S; Udayasankar J; Subramanian SL; Kahn SE
    Diabetologia; 2011 Jul; 54(7):1756-65. PubMed ID: 21484213
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Beta-cell deficit due to increased apoptosis in the human islet amyloid polypeptide transgenic (HIP) rat recapitulates the metabolic defects present in type 2 diabetes.
    Matveyenko AV; Butler PC
    Diabetes; 2006 Jul; 55(7):2106-14. PubMed ID: 16804082
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CHOP Contributes to, But Is Not the Only Mediator of, IAPP Induced β-Cell Apoptosis.
    Gurlo T; Rivera JF; Butler AE; Cory M; Hoang J; Costes S; Butler PC
    Mol Endocrinol; 2016 Apr; 30(4):446-54. PubMed ID: 26900721
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Induction of endoplasmic reticulum stress-induced beta-cell apoptosis and accumulation of polyubiquitinated proteins by human islet amyloid polypeptide.
    Huang CJ; Haataja L; Gurlo T; Butler AE; Wu X; Soeller WC; Butler PC
    Am J Physiol Endocrinol Metab; 2007 Dec; 293(6):E1656-62. PubMed ID: 17911343
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Successful versus failed adaptation to high-fat diet-induced insulin resistance: the role of IAPP-induced beta-cell endoplasmic reticulum stress.
    Matveyenko AV; Gurlo T; Daval M; Butler AE; Butler PC
    Diabetes; 2009 Apr; 58(4):906-16. PubMed ID: 19151199
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Formation of islet amyloid fibrils in beta-secretory granules of transgenic mice expressing human islet amyloid polypeptide/amylin.
    Yagui K; Yamaguchi T; Kanatsuka A; Shimada F; Huang CI; Tokuyama Y; Ohsawa H; Yamamura K; Miyazaki J; Mikata A
    Eur J Endocrinol; 1995 Apr; 132(4):487-96. PubMed ID: 7711888
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Islet amyloid inhibitors improve glucose homeostasis in a transgenic mouse model of type 2 diabetes.
    Wijesekara N; Ahrens R; Wu L; Ha K; Liu Y; Wheeler MB; Fraser PE
    Diabetes Obes Metab; 2015 Oct; 17(10):1003-6. PubMed ID: 26095311
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Islet amyloid polypeptide: a review of its biology and potential roles in the pathogenesis of diabetes mellitus.
    O'Brien TD; Butler PC; Westermark P; Johnson KH
    Vet Pathol; 1993 Jul; 30(4):317-32. PubMed ID: 8212454
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide.
    Verchere CB; D'Alessio DA; Palmiter RD; Weir GC; Bonner-Weir S; Baskin DG; Kahn SE
    Proc Natl Acad Sci U S A; 1996 Apr; 93(8):3492-6. PubMed ID: 8622964
    [TBL] [Abstract][Full Text] [Related]  

  • 20. RAGE binds preamyloid IAPP intermediates and mediates pancreatic β cell proteotoxicity.
    Abedini A; Cao P; Plesner A; Zhang J; He M; Derk J; Patil SA; Rosario R; Lonier J; Song F; Koh H; Li H; Raleigh DP; Schmidt AM
    J Clin Invest; 2018 Feb; 128(2):682-698. PubMed ID: 29337308
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.