213 related articles for article (PubMed ID: 16809075)
1. Etoposide and illegitimate DNA double-strand break repair in the generation of MLL translocations: new insights and new questions.
Sung PA; Libura J; Richardson C
DNA Repair (Amst); 2006 Sep; 5(9-10):1109-18. PubMed ID: 16809075
[TBL] [Abstract][Full Text] [Related]
2. Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia: correlation with scaffold attachment regions and topoisomerase II consensus binding sites.
Broeker PL; Super HG; Thirman MJ; Pomykala H; Yonebayashi Y; Tanabe S; Zeleznik-Le N; Rowley JD
Blood; 1996 Mar; 87(5):1912-22. PubMed ID: 8634439
[TBL] [Abstract][Full Text] [Related]
3. Assessing acute myeloid leukemia susceptibility in rearrangement-driven patients by DNA breakage at topoisomerase II and CCCTC-binding factor/cohesin binding sites.
Atkin ND; Raimer HM; Wang Z; Zang C; Wang YH
Genes Chromosomes Cancer; 2021 Dec; 60(12):808-821. PubMed ID: 34405474
[TBL] [Abstract][Full Text] [Related]
4. Model for MLL translocations in therapy-related leukemia involving topoisomerase IIβ-mediated DNA strand breaks and gene proximity.
Cowell IG; Sondka Z; Smith K; Lee KC; Manville CM; Sidorczuk-Lesthuruge M; Rance HA; Padget K; Jackson GH; Adachi N; Austin CA
Proc Natl Acad Sci U S A; 2012 Jun; 109(23):8989-94. PubMed ID: 22615413
[TBL] [Abstract][Full Text] [Related]
5. Molecular analysis of 13 cases of MLL/11q23 secondary acute leukemia and identification of topoisomerase II consensus-binding sequences near the chromosomal breakpoint of a secondary leukemia with the t(4;11).
Domer PH; Head DR; Renganathan N; Raimondi SC; Yang E; Atlas M
Leukemia; 1995 Aug; 9(8):1305-12. PubMed ID: 7643617
[TBL] [Abstract][Full Text] [Related]
6. Rearrangements of the MLL gene in therapy-related acute myeloid leukemia in patients previously treated with agents targeting DNA-topoisomerase II.
Super HJ; McCabe NR; Thirman MJ; Larson RA; Le Beau MM; Pedersen-Bjergaard J; Philip P; Diaz MO; Rowley JD
Blood; 1993 Dec; 82(12):3705-11. PubMed ID: 8260707
[TBL] [Abstract][Full Text] [Related]
7. Near-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocation.
Lovett BD; Lo Nigro L; Rappaport EF; Blair IA; Osheroff N; Zheng N; Megonigal MD; Williams WR; Nowell PC; Felix CA
Proc Natl Acad Sci U S A; 2001 Aug; 98(17):9802-7. PubMed ID: 11493704
[TBL] [Abstract][Full Text] [Related]
8. MLL rearrangements are induced by low doses of etoposide in human fetal hematopoietic stem cells.
Moneypenny CG; Shao J; Song Y; Gallagher EP
Carcinogenesis; 2006 Apr; 27(4):874-81. PubMed ID: 16377807
[TBL] [Abstract][Full Text] [Related]
9. An in vivo topoisomerase II cleavage site and a DNase I hypersensitive site colocalize near exon 9 in the MLL breakpoint cluster region.
Strissel PL; Strick R; Rowley JD; Zeleznik-Le NJ
Blood; 1998 Nov; 92(10):3793-803. PubMed ID: 9808573
[TBL] [Abstract][Full Text] [Related]
10. Secondary leukemias induced by topoisomerase-targeted drugs.
Felix CA
Biochim Biophys Acta; 1998 Oct; 1400(1-3):233-55. PubMed ID: 9748598
[TBL] [Abstract][Full Text] [Related]
11. Reciprocal DNA topoisomerase II cleavage events at 5'-TATTA-3' sequences in MLL and AF-9 create homologous single-stranded overhangs that anneal to form der(11) and der(9) genomic breakpoint junctions in treatment-related AML without further processing.
Whitmarsh RJ; Saginario C; Zhuo Y; Hilgenfeld E; Rappaport EF; Megonigal MD; Carroll M; Liu M; Osheroff N; Cheung NK; Slater DJ; Ried T; Knutsen T; Blair IA; Felix CA
Oncogene; 2003 Nov; 22(52):8448-59. PubMed ID: 14627986
[TBL] [Abstract][Full Text] [Related]
12. The broken MLL gene is frequently located outside the inherent chromosome territory in human lymphoid cells treated with DNA topoisomerase II poison etoposide.
Glukhov SI; Rubtsov MA; Alexeyevsky DA; Alexeevski AV; Razin SV; Iarovaia OV
PLoS One; 2013; 8(9):e75871. PubMed ID: 24086652
[TBL] [Abstract][Full Text] [Related]
13. Therapy-related acute myeloid leukemia-like MLL rearrangements are induced by etoposide in primary human CD34+ cells and remain stable after clonal expansion.
Libura J; Slater DJ; Felix CA; Richardson C
Blood; 2005 Mar; 105(5):2124-31. PubMed ID: 15528316
[TBL] [Abstract][Full Text] [Related]
14. Etoposide metabolites enhance DNA topoisomerase II cleavage near leukemia-associated MLL translocation breakpoints.
Lovett BD; Strumberg D; Blair IA; Pang S; Burden DA; Megonigal MD; Rappaport EF; Rebbeck TR; Osheroff N; Pommier YG; Felix CA
Biochemistry; 2001 Feb; 40(5):1159-70. PubMed ID: 11170441
[TBL] [Abstract][Full Text] [Related]
15. Topoisomerase II and the etiology of chromosomal translocations.
Felix CA; Kolaris CP; Osheroff N
DNA Repair (Amst); 2006 Sep; 5(9-10):1093-108. PubMed ID: 16857431
[TBL] [Abstract][Full Text] [Related]
16. Topoisomerase II inhibitors induce DNA double-strand breaks at a specific site within the AML1 locus.
Stanulla M; Wang J; Chervinsky DS; Aplan PD
Leukemia; 1997 Apr; 11(4):490-6. PubMed ID: 9096688
[TBL] [Abstract][Full Text] [Related]
17. Chromatin structural elements and chromosomal translocations in leukemia.
Zhang Y; Rowley JD
DNA Repair (Amst); 2006 Sep; 5(9-10):1282-97. PubMed ID: 16893685
[TBL] [Abstract][Full Text] [Related]
18. Analysis of t(9;11) chromosomal breakpoint sequences in childhood acute leukemia: almost identical MLL breakpoints in therapy-related AML after treatment without etoposides.
Langer T; Metzler M; Reinhardt D; Viehmann S; Borkhardt A; Reichel M; Stanulla M; Schrappe M; Creutzig U; Ritter J; Leis T; Jacobs U; Harbott J; Beck JD; Rascher W; Repp R
Genes Chromosomes Cancer; 2003 Apr; 36(4):393-401. PubMed ID: 12619163
[TBL] [Abstract][Full Text] [Related]
19. Bioflavonoids cause DNA double-strand breaks and chromosomal translocations through topoisomerase II-dependent and -independent mechanisms.
Goodenow D; Emmanuel F; Berman C; Sahyouni M; Richardson C
Mutat Res Genet Toxicol Environ Mutagen; 2020 Jan; 849():503144. PubMed ID: 32087851
[TBL] [Abstract][Full Text] [Related]
20. Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia.
Strick R; Strissel PL; Borgers S; Smith SL; Rowley JD
Proc Natl Acad Sci U S A; 2000 Apr; 97(9):4790-5. PubMed ID: 10758153
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]