BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

203 related articles for article (PubMed ID: 16814542)

  • 21. Discovery and SAR of 4-amino-2-biarylbutylurea MCH 1 receptor antagonists through solid-phase parallel synthesis.
    Guo T; Hunter RC; Gu H; Rokosz LL; Stauffer TM; Hobbs DW
    Bioorg Med Chem Lett; 2005 Aug; 15(16):3691-5. PubMed ID: 15953726
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Identification of substituted 4-aminopiperidines and 3-aminopyrrolidines as potent MCH-R1 antagonists for the treatment of obesity.
    Kim N; Meyers KM; Mendez-Andino JL; Warshakoon NC; Ji W; Wos JA; Colson A; Mitchell MC; Davis JR; Pinney BB; Reizes O; Hu XE
    Bioorg Med Chem Lett; 2006 Oct; 16(20):5445-50. PubMed ID: 16879961
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Heteroaryl beta-tetralin ureas as novel antagonists of human TRPV1.
    Jetter MC; Youngman MA; McNally JJ; McDonnell ME; Zhang SP; Dubin AE; Nasser N; Codd EE; Flores CM; Dax SL
    Bioorg Med Chem Lett; 2007 Nov; 17(22):6160-3. PubMed ID: 17892935
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Novel series of substituted biphenylmethyl urea derivatives as MCH-R1 antagonists for the treatment of obesity.
    Galiano S; Ceras J; Cirauqui N; Pérez S; Juanenea L; Rivera G; Aldana I; Monge A
    Bioorg Med Chem; 2007 Jun; 15(11):3896-911. PubMed ID: 17407817
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Design and synthesis of novel hydantoin-containing melanin-concentrating hormone receptor antagonists.
    Balavoine F; Malabre P; Alleaume T; Rey A; Cherfils V; Jeanneton O; Seigneurin-Venin S; Revah F
    Bioorg Med Chem Lett; 2007 Jul; 17(13):3754-9. PubMed ID: 17448659
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Benzimidazoles as non-peptide luteinizing hormone-releasing hormone (LHRH) antagonists. Part 3: Discovery of 1-(1H-benzimidazol-5-yl)-3-tert-butylurea derivatives.
    Tatsuta M; Kataoka M; Yasoshima K; Sakakibara S; Shogase Y; Shimazaki M; Yura T; Li Y; Yamamoto N; Gupta J; Urbahns K
    Bioorg Med Chem Lett; 2005 May; 15(9):2265-9. PubMed ID: 15837306
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Potent antagonists of the CCR2b receptor. Part 3: SAR of the (R)-3-aminopyrrolidine series.
    Moree WJ; Kataoka K; Ramirez-Weinhouse MM; Shiota T; Imai M; Tsutsumi T; Sudo M; Endo N; Muroga Y; Hada T; Fanning D; Saunders J; Kato Y; Myers PL; Tarby CM
    Bioorg Med Chem Lett; 2008 Mar; 18(6):1869-73. PubMed ID: 18313297
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Discovery of 1,3-disubstituted-1H-pyrrole derivatives as potent melanin-concentrating hormone receptor 1 (MCH-R1) antagonists.
    Berglund S; Egner BJ; Gradén H; Gradén J; Morgan DG; Inghardt T; Giordanetto F
    Bioorg Med Chem Lett; 2008 Sep; 18(17):4859-63. PubMed ID: 18682323
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Synthesis and evaluation of urea-based indazoles as melanin-concentrating hormone receptor 1 antagonists for the treatment of obesity.
    Souers AJ; Gao J; Wodka D; Judd AS; Mulhern MM; Napier JJ; Brune ME; Bush EN; Brodjian SJ; Dayton BD; Shapiro R; Hernandez LE; Marsh KC; Sham HL; Collins CA; Kym PR
    Bioorg Med Chem Lett; 2005 Jun; 15(11):2752-7. PubMed ID: 15911251
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Synthesis and biological evaluation of 3-aminopyrrolidine derivatives as CC chemokine receptor 2 antagonists.
    Lim JW; Oh Y; Kim JH; Oak MH; Na Y; Lee JO; Lee SW; Cho H; Park WK; Choi G; Kang J
    Bioorg Med Chem Lett; 2010 Apr; 20(7):2099-102. PubMed ID: 20223662
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Design and optimization of quinazoline derivatives as melanin concentrating hormone receptor 1 (MCHR1) antagonists.
    Sasmal S; Balaji G; Kanna Reddy HR; Balasubrahmanyam D; Srinivas G; Kyasa SK; Sasmal PK; Khanna I; Talwar R; Suresh J; Jadhav VP; Muzeeb S; Shashikumar D; Harinder Reddy K; Sebastian VJ; Frimurer TM; Rist Ø; Elster L; Högberg T
    Bioorg Med Chem Lett; 2012 May; 22(9):3157-62. PubMed ID: 22487182
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Biaryl ureas as potent and orally efficacious melanin concentrating hormone receptor 1 antagonists for the treatment of obesity.
    Palani A; Shapiro S; McBriar MD; Clader JW; Greenlee WJ; Spar B; Kowalski TJ; Farley C; Cook J; van Heek M; Weig B; O'neill K; Graziano M; Hawes B
    J Med Chem; 2005 Jul; 48(15):4746-9. PubMed ID: 16033253
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Biaryl diamides as potent melanin concentrating hormone receptor 1 antagonists.
    Palani A; Shapiro S; McBriar MD; Clader JW; Greenlee WJ; O'Neill K; Hawes B
    Bioorg Med Chem Lett; 2005 Dec; 15(23):5234-6. PubMed ID: 16202583
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Novel pyrrolidine ureas as C-C chemokine receptor 1 (CCR1) antagonists.
    Merritt JR; Liu J; Quadros E; Morris ML; Liu R; Zhang R; Jacob B; Postelnek J; Hicks CM; Chen W; Kimble EF; Rogers WL; O'Brien L; White N; Desai H; Bansal S; King G; Ohlmeyer MJ; Appell KC; Webb ML
    J Med Chem; 2009 Mar; 52(5):1295-301. PubMed ID: 19183043
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Substituted chromones and quinolones as potent melanin-concentrating hormone receptor 1 antagonists.
    Dyck B; Zhao L; Tamiya J; Pontillo J; Hudson S; Ching B; Heise CE; Wen J; Norton C; Madan A; Schwarz D; Wade W; Goodfellow VS
    Bioorg Med Chem Lett; 2006 Aug; 16(16):4237-42. PubMed ID: 16762549
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Discovery and structure-activity relationships of urea derivatives as potent and novel CCR3 antagonists.
    Nitta A; Iura Y; Tomioka H; Sato I; Morihira K; Kubota H; Morokata T; Takeuchi M; Ohta M; Tsukamoto S; Imaoka T; Takahashi T
    Bioorg Med Chem Lett; 2012 Aug; 22(15):4951-4. PubMed ID: 22749826
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Synthesis and SAR investigations of novel 2-arylbenzimidazole derivatives as melanin-concentrating hormone receptor 1 (MCH-R1) antagonists.
    Lim CJ; Kim N; Lee EK; Lee BH; Oh KS; Yoo SE; Yi KY
    Bioorg Med Chem Lett; 2011 Apr; 21(8):2309-12. PubMed ID: 21420863
    [TBL] [Abstract][Full Text] [Related]  

  • 38. A novel series of piperazinyl-pyridine ureas as antagonists of the purinergic P2Y12 receptor.
    Bach P; Boström J; Brickmann K; van Giezen JJ; Hovland R; Petersson AU; Ray A; Zetterberg F
    Bioorg Med Chem Lett; 2011 May; 21(10):2877-81. PubMed ID: 21507636
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Design and synthesis of indane-ureido-thioisobutyric acids: A novel class of PPARalpha agonists.
    Matthews JM; Chen X; Cryan E; Hlasta DJ; Rybczynski PJ; Strauss K; Tang Y; Xu JZ; Yang M; Zhou L; Demarest KT
    Bioorg Med Chem Lett; 2007 Dec; 17(24):6773-8. PubMed ID: 18029176
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Discovery of a novel series of melanin-concentrating hormone receptor 1 antagonists for the treatment of obesity.
    Mihalic JT; Chen X; Fan P; Chen X; Fu Y; Liang L; Reed M; Tang L; Chen JL; Jaen J; Li L; Dai K
    Bioorg Med Chem Lett; 2011 Dec; 21(23):7001-5. PubMed ID: 22019296
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.