371 related articles for article (PubMed ID: 16818503)
1. The synthetic triterpenoid CDDO-imidazolide induces monocytic differentiation by activating the Smad and ERK signaling pathways in HL60 leukemia cells.
Ji Y; Lee HJ; Goodman C; Uskokovic M; Liby K; Sporn M; Suh N
Mol Cancer Ther; 2006 Jun; 5(6):1452-8. PubMed ID: 16818503
[TBL] [Abstract][Full Text] [Related]
2. Synthetic triterpenoids enhance transforming growth factor beta/Smad signaling.
Suh N; Roberts AB; Birkey Reffey S; Miyazono K; Itoh S; ten Dijke P; Heiss EH; Place AE; Risingsong R; Williams CR; Honda T; Gribble GW; Sporn MB
Cancer Res; 2003 Mar; 63(6):1371-6. PubMed ID: 12649201
[TBL] [Abstract][Full Text] [Related]
3. The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid-imidazolide alters transforming growth factor beta-dependent signaling and cell migration by affecting the cytoskeleton and the polarity complex.
To C; Kulkarni S; Pawson T; Honda T; Gribble GW; Sporn MB; Wrana JL; Di Guglielmo GM
J Biol Chem; 2008 Apr; 283(17):11700-13. PubMed ID: 18283107
[TBL] [Abstract][Full Text] [Related]
4. The novel synthetic triterpenoid, CDDO-imidazolide, inhibits inflammatory response and tumor growth in vivo.
Place AE; Suh N; Williams CR; Risingsong R; Honda T; Honda Y; Gribble GW; Leesnitzer LM; Stimmel JB; Willson TM; Rosen E; Sporn MB
Clin Cancer Res; 2003 Jul; 9(7):2798-806. PubMed ID: 12855660
[TBL] [Abstract][Full Text] [Related]
5. Methanol extract of Antrodia cinnamomea mycelia induces phenotypic and functional differentiation of HL60 into monocyte-like cells via an ERK/CEBP-β signaling pathway.
Wen CL; Teng CL; Chiang CH; Chang CC; Hwang WL; Kuo CL; Hsu SL
Phytomedicine; 2012 Mar; 19(5):424-35. PubMed ID: 22293124
[TBL] [Abstract][Full Text] [Related]
6. Peroxisome proliferator-activated receptor-gamma-independent repression of collagenase gene expression by 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid and prostaglandin 15-deoxy-delta(12,14) J2: a role for Smad signaling.
Mix KS; Coon CI; Rosen ED; Suh N; Sporn MB; Brinckerhoff CE
Mol Pharmacol; 2004 Feb; 65(2):309-18. PubMed ID: 14742672
[TBL] [Abstract][Full Text] [Related]
7. Transcriptional cross-talk between Smad, ERK1/2, and p38 mitogen-activated protein kinase pathways regulates transforming growth factor-beta-induced aggrecan gene expression in chondrogenic ATDC5 cells.
Watanabe H; de Caestecker MP; Yamada Y
J Biol Chem; 2001 Apr; 276(17):14466-73. PubMed ID: 11278290
[TBL] [Abstract][Full Text] [Related]
8. The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling.
Liby K; Hock T; Yore MM; Suh N; Place AE; Risingsong R; Williams CR; Royce DB; Honda T; Honda Y; Gribble GW; Hill-Kapturczak N; Agarwal A; Sporn MB
Cancer Res; 2005 Jun; 65(11):4789-98. PubMed ID: 15930299
[TBL] [Abstract][Full Text] [Related]
9. A synthetic triterpenoid CDDO-Im inhibits tumorsphere formation by regulating stem cell signaling pathways in triple-negative breast cancer.
So JY; Lin JJ; Wahler J; Liby KT; Sporn MB; Suh N
PLoS One; 2014; 9(9):e107616. PubMed ID: 25229616
[TBL] [Abstract][Full Text] [Related]
10. CDDO induces granulocytic differentiation of myeloid leukemic blasts through translational up-regulation of p42 CCAAT enhancer binding protein alpha.
Koschmieder S; D'Alò F; Radomska H; Schöneich C; Chang JS; Konopleva M; Kobayashi S; Levantini E; Suh N; Di Ruscio A; Voso MT; Watt JC; Santhanam R; Sargin B; Kantarjian H; Andreeff M; Sporn MB; Perrotti D; Berdel WE; Müller-Tidow C; Serve H; Tenen DG
Blood; 2007 Nov; 110(10):3695-705. PubMed ID: 17671235
[TBL] [Abstract][Full Text] [Related]
11. CDDO-Im is a stimulator of megakaryocytic differentiation.
Petronelli A; Pelosi E; Santoro S; Saulle E; Cerio AM; Mariani G; Labbaye C; Testa U
Leuk Res; 2011 Apr; 35(4):534-44. PubMed ID: 21035854
[TBL] [Abstract][Full Text] [Related]
12. A novel vitamin D derivative activates bone morphogenetic protein signaling in MCF10 breast epithelial cells.
Lee HJ; Wislocki A; Goodman C; Ji Y; Ge R; Maehr H; Uskokovic M; Reiss M; Suh N
Mol Pharmacol; 2006 Jun; 69(6):1840-8. PubMed ID: 16533909
[TBL] [Abstract][Full Text] [Related]
13. Induction of redox imbalance and apoptosis in multiple myeloma cells by the novel triterpenoid 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid.
Ikeda T; Nakata Y; Kimura F; Sato K; Anderson K; Motoyoshi K; Sporn M; Kufe D
Mol Cancer Ther; 2004 Jan; 3(1):39-45. PubMed ID: 14749474
[TBL] [Abstract][Full Text] [Related]
14. Synthetic triterpenoids, CDDO-Imidazolide and CDDO-Ethyl amide, induce chondrogenesis.
Suh N; Paul S; Lee HJ; Yoon T; Shah N; Son AI; Reddi AH; Medici D; Sporn MB
Osteoarthritis Cartilage; 2012 May; 20(5):446-450. PubMed ID: 22343171
[TBL] [Abstract][Full Text] [Related]
15. Levels of phospho-Smad2/3 are sensors of the interplay between effects of TGF-beta and retinoic acid on monocytic and granulocytic differentiation of HL-60 cells.
Cao Z; Flanders KC; Bertolette D; Lyakh LA; Wurthner JU; Parks WT; Letterio JJ; Ruscetti FW; Roberts AB
Blood; 2003 Jan; 101(2):498-507. PubMed ID: 12393416
[TBL] [Abstract][Full Text] [Related]
16. Triterpenoid CDDO-Im downregulates PML/RARalpha expression in acute promyelocytic leukemia cells.
Ikeda T; Kimura F; Nakata Y; Sato K; Ogura K; Motoyoshi K; Sporn M; Kufe D
Cell Death Differ; 2005 May; 12(5):523-31. PubMed ID: 15746941
[TBL] [Abstract][Full Text] [Related]
17. Electrophilic peroxisome proliferator-activated receptor-gamma ligands have potent antifibrotic effects in human lung fibroblasts.
Ferguson HE; Kulkarni A; Lehmann GM; Garcia-Bates TM; Thatcher TH; Huxlin KR; Phipps RP; Sime PJ
Am J Respir Cell Mol Biol; 2009 Dec; 41(6):722-30. PubMed ID: 19286977
[TBL] [Abstract][Full Text] [Related]
18. The bortezomib/proteasome inhibitor PS-341 and triterpenoid CDDO-Im induce synergistic anti-multiple myeloma (MM) activity and overcome bortezomib resistance.
Chauhan D; Li G; Podar K; Hideshima T; Shringarpure R; Catley L; Mitsiades C; Munshi N; Tai YT; Suh N; Gribble GW; Honda T; Schlossman R; Richardson P; Sporn MB; Anderson KC
Blood; 2004 Apr; 103(8):3158-66. PubMed ID: 15070698
[TBL] [Abstract][Full Text] [Related]
19. Synthetic triterpenoids cooperate with tumor necrosis factor-related apoptosis-inducing ligand to induce apoptosis of breast cancer cells.
Hyer ML; Croxton R; Krajewska M; Krajewski S; Kress CL; Lu M; Suh N; Sporn MB; Cryns VL; Zapata JM; Reed JC
Cancer Res; 2005 Jun; 65(11):4799-808. PubMed ID: 15930300
[TBL] [Abstract][Full Text] [Related]
20. The synthetic triterpenoid CDDO-Im inhibits fatty acid synthase expression and has antiproliferative and proapoptotic effects in human liposarcoma cells.
Hughes DT; Martel PM; Kinlaw WB; Eisenberg BL
Cancer Invest; 2008 Mar; 26(2):118-27. PubMed ID: 18259941
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]