1092 related articles for article (PubMed ID: 16819506)
1. Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine.
Roos WP; Batista LF; Naumann SC; Wick W; Weller M; Menck CF; Kaina B
Oncogene; 2007 Jan; 26(2):186-97. PubMed ID: 16819506
[TBL] [Abstract][Full Text] [Related]
2. Apoptosis triggered by DNA damage O6-methylguanine in human lymphocytes requires DNA replication and is mediated by p53 and Fas/CD95/Apo-1.
Roos W; Baumgartner M; Kaina B
Oncogene; 2004 Jan; 23(2):359-67. PubMed ID: 14724564
[TBL] [Abstract][Full Text] [Related]
3. Apoptosis induced by DNA damage O6-methylguanine is Bcl-2 and caspase-9/3 regulated and Fas/caspase-8 independent.
Ochs K; Kaina B
Cancer Res; 2000 Oct; 60(20):5815-24. PubMed ID: 11059778
[TBL] [Abstract][Full Text] [Related]
4. Delayed repletion of O6-methylguanine-DNA methyltransferase resulting in failure to protect the human glioblastoma cell line SF767 from temozolomide-induced cytotoxicity.
Hirose Y; Kreklau EL; Erickson LC; Berger MS; Pieper RO
J Neurosurg; 2003 Mar; 98(3):591-8. PubMed ID: 12650433
[TBL] [Abstract][Full Text] [Related]
5. Brca2/Xrcc2 dependent HR, but not NHEJ, is required for protection against O(6)-methylguanine triggered apoptosis, DSBs and chromosomal aberrations by a process leading to SCEs.
Roos WP; Nikolova T; Quiros S; Naumann SC; Kiedron O; Zdzienicka MZ; Kaina B
DNA Repair (Amst); 2009 Jan; 8(1):72-86. PubMed ID: 18840549
[TBL] [Abstract][Full Text] [Related]
6. O6-methylguanine DNA methyltransferase and p53 status predict temozolomide sensitivity in human malignant glioma cells.
Hermisson M; Klumpp A; Wick W; Wischhusen J; Nagel G; Roos W; Kaina B; Weller M
J Neurochem; 2006 Feb; 96(3):766-76. PubMed ID: 16405512
[TBL] [Abstract][Full Text] [Related]
7. Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53.
Naumann SC; Roos WP; Jöst E; Belohlavek C; Lennerz V; Schmidt CW; Christmann M; Kaina B
Br J Cancer; 2009 Jan; 100(2):322-33. PubMed ID: 19127257
[TBL] [Abstract][Full Text] [Related]
8. The L84F polymorphic variant of human O6-methylguanine-DNA methyltransferase alters stability in U87MG glioma cells but not temozolomide sensitivity.
Remington M; Chtchetinin J; Ancheta K; Nghiemphu PL; Cloughesy T; Lai A
Neuro Oncol; 2009 Feb; 11(1):22-32. PubMed ID: 18812520
[TBL] [Abstract][Full Text] [Related]
9. Effect of chemotherapy-induced DNA repair on oncolytic herpes simplex viral replication.
Aghi M; Rabkin S; Martuza RL
J Natl Cancer Inst; 2006 Jan; 98(1):38-50. PubMed ID: 16391370
[TBL] [Abstract][Full Text] [Related]
10. Processing of O6-methylguanine into DNA double-strand breaks requires two rounds of replication whereas apoptosis is also induced in subsequent cell cycles.
Quiros S; Roos WP; Kaina B
Cell Cycle; 2010 Jan; 9(1):168-78. PubMed ID: 20016283
[TBL] [Abstract][Full Text] [Related]
11. Activation of AMP-activated protein kinase by temozolomide contributes to apoptosis in glioblastoma cells via p53 activation and mTORC1 inhibition.
Zhang WB; Wang Z; Shu F; Jin YH; Liu HY; Wang QJ; Yang Y
J Biol Chem; 2010 Dec; 285(52):40461-71. PubMed ID: 20880848
[TBL] [Abstract][Full Text] [Related]
12. Temozolomide-mediated DNA methylation in human myeloid precursor cells: differential involvement of intrinsic and extrinsic apoptotic pathways.
Wang H; Cai S; Ernstberger A; Bailey BJ; Wang MZ; Cai W; Goebel WS; Czader MB; Crean C; Suvannasankha A; Shokolenkoc I; Wilson GL; Baluyut AR; Mayo LD; Pollok KE
Clin Cancer Res; 2013 May; 19(10):2699-709. PubMed ID: 23536437
[TBL] [Abstract][Full Text] [Related]
13. Biochemical changes associated with a multidrug-resistant phenotype of a human glioma cell line with temozolomide-acquired resistance.
Ma J; Murphy M; O'Dwyer PJ; Berman E; Reed K; Gallo JM
Biochem Pharmacol; 2002 Apr; 63(7):1219-28. PubMed ID: 11960598
[TBL] [Abstract][Full Text] [Related]
14. Multifaceted resistance of gliomas to temozolomide.
Bocangel DB; Finkelstein S; Schold SC; Bhakat KK; Mitra S; Kokkinakis DM
Clin Cancer Res; 2002 Aug; 8(8):2725-34. PubMed ID: 12171906
[TBL] [Abstract][Full Text] [Related]
15. p53 mutant human glioma cells are sensitive to UV-C-induced apoptosis due to impaired cyclobutane pyrimidine dimer removal.
Batista LF; Roos WP; Kaina B; Menck CF
Mol Cancer Res; 2009 Feb; 7(2):237-46. PubMed ID: 19208740
[TBL] [Abstract][Full Text] [Related]
16. Survival and death strategies in glioma cells: autophagy, senescence and apoptosis triggered by a single type of temozolomide-induced DNA damage.
Knizhnik AV; Roos WP; Nikolova T; Quiros S; Tomaszowski KH; Christmann M; Kaina B
PLoS One; 2013; 8(1):e55665. PubMed ID: 23383259
[TBL] [Abstract][Full Text] [Related]
17. Nijmegen breakage syndrome protein (NBN) causes resistance to methylating anticancer drugs such as temozolomide.
Eich M; Roos WP; Dianov GL; Digweed M; Kaina B
Mol Pharmacol; 2010 Nov; 78(5):943-51. PubMed ID: 20729302
[TBL] [Abstract][Full Text] [Related]
18. Are There Thresholds in Glioblastoma Cell Death Responses Triggered by Temozolomide?
He Y; Kaina B
Int J Mol Sci; 2019 Mar; 20(7):. PubMed ID: 30925722
[TBL] [Abstract][Full Text] [Related]
19. N3-substituted temozolomide analogs overcome methylguanine-DNA methyltransferase and mismatch repair precipitating apoptotic and autophagic cancer cell death.
Zhang J; Hummersone M; Matthews CS; Stevens MF; Bradshaw TD
Oncology; 2015; 88(1):28-48. PubMed ID: 25277441
[TBL] [Abstract][Full Text] [Related]
20. Effect of aberrant p53 function on temozolomide sensitivity of glioma cell lines and brain tumor initiating cells from glioblastoma.
Blough MD; Beauchamp DC; Westgate MR; Kelly JJ; Cairncross JG
J Neurooncol; 2011 Mar; 102(1):1-7. PubMed ID: 20593219
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
