57 related articles for article (PubMed ID: 16821585)
21. UGT1A1*28 genotype affects the in-vitro glucuronidation of thyroxine in human livers.
Yoder Graber AL; Ramírez J; Innocenti F; Ratain MJ
Pharmacogenet Genomics; 2007 Aug; 17(8):619-27. PubMed ID: 17622938
[TBL] [Abstract][Full Text] [Related]
22. Schedule-dependent cytotoxicity of SN-38 in p53 wild-type and mutant colon adenocarcinoma cell lines.
te Poele RH; Joel SP
Br J Cancer; 1999 Dec; 81(8):1285-93. PubMed ID: 10604724
[TBL] [Abstract][Full Text] [Related]
23. The novel UGT1A9 intronic I399 polymorphism appears as a predictor of 7-ethyl-10-hydroxycamptothecin glucuronidation levels in the liver.
Girard H; Villeneuve L; Court MH; Fortier LC; Caron P; Hao Q; von Moltke LL; Greenblatt DJ; Guillemette C
Drug Metab Dispos; 2006 Jul; 34(7):1220-8. PubMed ID: 16595709
[TBL] [Abstract][Full Text] [Related]
24. UDP-glucuronosyltransferase 1A compromises intracellular accumulation and anti-cancer effect of tanshinone IIA in human colon cancer cells.
Liu M; Wang Q; Liu F; Cheng X; Wu X; Wang H; Wu M; Ma Y; Wang G; Hao H
PLoS One; 2013; 8(11):e79172. PubMed ID: 24244442
[TBL] [Abstract][Full Text] [Related]
25. Expression and characterization of a human carboxylesterase 2 splice variant.
Schiel MA; Green SL; Davis WI; Sanghani PC; Bosron WF; Sanghani SP
J Pharmacol Exp Ther; 2007 Oct; 323(1):94-101. PubMed ID: 17636009
[TBL] [Abstract][Full Text] [Related]
26. Cell cycle effects of the novel topoisomerase I inhibitor NU/ICRF 505 in a panel of Chinese hamster ovary cell lines.
Macpherson JS; Cummings J; Meikle I; Miller EP; Smyth JF
Eur J Cancer; 1997 Feb; 33(2):280-3. PubMed ID: 9135500
[TBL] [Abstract][Full Text] [Related]
27. Aberrant expression of OX1 receptors for orexins in colon cancers and liver metastases: an openable gate to apoptosis.
Voisin T; El Firar A; Fasseu M; Rouyer-Fessard C; Descatoire V; Walker F; Paradis V; Bedossa P; Henin D; Lehy T; Laburthe M
Cancer Res; 2011 May; 71(9):3341-51. PubMed ID: 21415167
[TBL] [Abstract][Full Text] [Related]
28. Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism.
Iyer L; Hall D; Das S; Mortell MA; Ramírez J; Kim S; Di Rienzo A; Ratain MJ
Clin Pharmacol Ther; 1999 May; 65(5):576-82. PubMed ID: 10340924
[TBL] [Abstract][Full Text] [Related]
29. Identification of UDP-glucuronosyltransferase isoforms responsible for leonurine glucuronidation in human liver and intestinal microsomes.
Tan B; Cai W; Zhang J; Zhou N; Ma G; Yang P; Zhu Q; Zhu Y
Xenobiotica; 2014 Sep; 44(9):775-84. PubMed ID: 24635759
[TBL] [Abstract][Full Text] [Related]
30. Functional characterization of human UDP-glucuronosyltransferase 1A9 variant, D256N, found in Japanese cancer patients.
Jinno H; Saeki M; Saito Y; Tanaka-Kagawa T; Hanioka N; Sai K; Kaniwa N; Ando M; Shirao K; Minami H; Ohtsu A; Yoshida T; Saijo N; Ozawa S; Sawada J
J Pharmacol Exp Ther; 2003 Aug; 306(2):688-93. PubMed ID: 12730278
[TBL] [Abstract][Full Text] [Related]
31. Influence of genetic variants in UGT1A1 and UGT1A9 on the in vivo glucuronidation of SN-38.
Paoluzzi L; Singh AS; Price DK; Danesi R; Mathijssen RH; Verweij J; Figg WD; Sparreboom A
J Clin Pharmacol; 2004 Aug; 44(8):854-60. PubMed ID: 15286088
[TBL] [Abstract][Full Text] [Related]
32. The glucuronidation of Delta4-3-Keto C19- and C21-hydroxysteroids by human liver microsomal and recombinant UDP-glucuronosyltransferases (UGTs): 6alpha- and 21-hydroxyprogesterone are selective substrates for UGT2B7.
Bowalgaha K; Elliot DJ; Mackenzie PI; Knights KM; Miners JO
Drug Metab Dispos; 2007 Mar; 35(3):363-70. PubMed ID: 17151189
[TBL] [Abstract][Full Text] [Related]
33. Studies on the substrate specificity of human intestinal UDP- lucuronosyltransferases 1A8 and 1A10.
Cheng Z; Radominska-Pandya A; Tephly TR
Drug Metab Dispos; 1999 Oct; 27(10):1165-70. PubMed ID: 10497143
[TBL] [Abstract][Full Text] [Related]
34. The impact of glucuronidation on the bioactivation and DNA adduction of the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in vivo.
Malfatti MA; Ubick EA; Felton JS
Carcinogenesis; 2005 Nov; 26(11):2019-28. PubMed ID: 15944213
[TBL] [Abstract][Full Text] [Related]
35. Modulation of glucuronidation of SN-38, the active metabolite of irinotecan, by valproic acid and phenobarbital.
Gupta E; Wang X; Ramirez J; Ratain MJ
Cancer Chemother Pharmacol; 1997; 39(5):440-4. PubMed ID: 9054958
[TBL] [Abstract][Full Text] [Related]
36. Secreted and tumour targeted human carboxylesterase for activation of irinotecan.
Oosterhoff D; Pinedo HM; van der Meulen IH; de Graaf M; Sone T; Kruyt FA; van Beusechem VW; Haisma HJ; Gerritsen WR
Br J Cancer; 2002 Sep; 87(6):659-64. PubMed ID: 12237777
[TBL] [Abstract][Full Text] [Related]
37. Effects of ketoconazole on glucuronidation by UDP-glucuronosyltransferase enzymes.
Yong WP; Ramirez J; Innocenti F; Ratain MJ
Clin Cancer Res; 2005 Sep; 11(18):6699-704. PubMed ID: 16166450
[TBL] [Abstract][Full Text] [Related]
38. Expression of drug pathway proteins is independent of tumour type.
Zhang W; Shannon WD; Duncan J; Scheffer GL; Scheper RJ; McLeod HL
J Pathol; 2006 Jun; 209(2):213-9. PubMed ID: 16508919
[TBL] [Abstract][Full Text] [Related]
39. Colon Cancer Cells Evade Drug Action by Enhancing Drug Metabolism.
Cong B; Thakur T; Uribe AH; Stamou E; Gopinath S; Maddocks O; Cagan R
bioRxiv; 2023 Dec; ():. PubMed ID: 38187524
[TBL] [Abstract][Full Text] [Related]
40. A targetable pathway to eliminate TRA-1-60+/TRA-1-81+ chemoresistant cancer cells.
Tan L; Duan X; Mutyala P; Zhou T; Amin S; Zhang T; Herbst B; Askan G; Itkin T; Xiang Z; Michelassi F; Lieberman MD; Iacobuzio-Donahue CA; Leach SD; Evans T; Chen S
J Mol Cell Biol; 2023 Nov; 15(6):. PubMed ID: 37327088
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]