BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 16822578)

  • 61. Abnormalities of epidermal growth factor receptor in lung squamous-cell carcinomas, adenosquamous carcinomas, and large-cell carcinomas: tyrosine kinase domain mutations are not rare in tumors with an adenocarcinoma component.
    Ohtsuka K; Ohnishi H; Fujiwara M; Kishino T; Matsushima S; Furuyashiki G; Takei H; Koshiishi Y; Goya T; Watanabe T
    Cancer; 2007 Feb; 109(4):741-50. PubMed ID: 17238183
    [TBL] [Abstract][Full Text] [Related]  

  • 62. No evidence for germline mutations of the LKB1/STK11 gene in familial pancreatic carcinoma.
    Grützmann R; McFaul C; Bartsch DK; Sina-Frey M; Rieder H; Koch R; McCarthy E; Greenhalf W; Neoptolemos JP; Saeger HD; Pilarsky C
    Cancer Lett; 2004 Oct; 214(1):63-8. PubMed ID: 15331174
    [TBL] [Abstract][Full Text] [Related]  

  • 63. Genetic screening for Peutz-Jeghers syndrome.
    Ballhausen WG; Günther K
    Expert Rev Mol Diagn; 2003 Jul; 3(4):471-9. PubMed ID: 12877386
    [TBL] [Abstract][Full Text] [Related]  

  • 64. Infrequent mutation of the human envoplakin gene is closely linked to the tylosis oesophageal cancer locus in sporadic oesophageal squamous cell carcinomas.
    Iwaya T; Maesawa C; Kimura T; Ogasawara S; Ikeda K; Kimura Y; Noda Y; Ishida K; Sato N; Saito K; Masuda T
    Oncol Rep; 2005 Apr; 13(4):703-7. PubMed ID: 15756445
    [TBL] [Abstract][Full Text] [Related]  

  • 65. LKB1 deficiency sensitizes mice to carcinogen-induced tumorigenesis.
    Gurumurthy S; Hezel AF; Sahin E; Berger JH; Bosenberg MW; Bardeesy N
    Cancer Res; 2008 Jan; 68(1):55-63. PubMed ID: 18172296
    [TBL] [Abstract][Full Text] [Related]  

  • 66. Frequency and spectrum of cancers in the Peutz-Jeghers syndrome.
    Hearle N; Schumacher V; Menko FH; Olschwang S; Boardman LA; Gille JJ; Keller JJ; Westerman AM; Scott RJ; Lim W; Trimbath JD; Giardiello FM; Gruber SB; Offerhaus GJ; de Rooij FW; Wilson JH; Hansmann A; Möslein G; Royer-Pokora B; Vogel T; Phillips RK; Spigelman AD; Houlston RS
    Clin Cancer Res; 2006 May; 12(10):3209-15. PubMed ID: 16707622
    [TBL] [Abstract][Full Text] [Related]  

  • 67. Thirteen new p53 gene mutants identified among 41 human breast cancer cell lines.
    Wasielewski M; Elstrodt F; Klijn JG; Berns EM; Schutte M
    Breast Cancer Res Treat; 2006 Sep; 99(1):97-101. PubMed ID: 16541312
    [TBL] [Abstract][Full Text] [Related]  

  • 68. LKB1 modulates lung cancer differentiation and metastasis.
    Ji H; Ramsey MR; Hayes DN; Fan C; McNamara K; Kozlowski P; Torrice C; Wu MC; Shimamura T; Perera SA; Liang MC; Cai D; Naumov GN; Bao L; Contreras CM; Li D; Chen L; Krishnamurthy J; Koivunen J; Chirieac LR; Padera RF; Bronson RT; Lindeman NI; Christiani DC; Lin X; Shapiro GI; Jänne PA; Johnson BE; Meyerson M; Kwiatkowski DJ; Castrillon DH; Bardeesy N; Sharpless NE; Wong KK
    Nature; 2007 Aug; 448(7155):807-10. PubMed ID: 17676035
    [TBL] [Abstract][Full Text] [Related]  

  • 69. Complete germline deletion of the STK11 gene in a family with Peutz-Jeghers syndrome.
    Le Meur N; Martin C; Saugier-Veber P; Joly G; Lemoine F; Moirot H; Rossi A; Bachy B; Cabot A; Joly P; Frébourg T
    Eur J Hum Genet; 2004 May; 12(5):415-8. PubMed ID: 14970844
    [TBL] [Abstract][Full Text] [Related]  

  • 70. A role for LKB1 gene in human cancer beyond the Peutz-Jeghers syndrome.
    Sanchez-Cespedes M
    Oncogene; 2007 Dec; 26(57):7825-32. PubMed ID: 17599048
    [TBL] [Abstract][Full Text] [Related]  

  • 71. Altered LKB1/CREB-regulated transcription co-activator (CRTC) signaling axis promotes esophageal cancer cell migration and invasion.
    Gu Y; Lin S; Li JL; Nakagawa H; Chen Z; Jin B; Tian L; Ucar DA; Shen H; Lu J; Hochwald SN; Kaye FJ; Wu L
    Oncogene; 2012 Jan; 31(4):469-79. PubMed ID: 21706049
    [TBL] [Abstract][Full Text] [Related]  

  • 72. The tumor suppressor LKB1 induces p21 expression in collaboration with LMO4, GATA-6, and Ldb1.
    Setogawa T; Shinozaki-Yabana S; Masuda T; Matsuura K; Akiyama T
    Biochem Biophys Res Commun; 2006 May; 343(4):1186-90. PubMed ID: 16580634
    [TBL] [Abstract][Full Text] [Related]  

  • 73. Somatic mutations of the protein kinase gene family in human lung cancer.
    Davies H; Hunter C; Smith R; Stephens P; Greenman C; Bignell G; Teague J; Butler A; Edkins S; Stevens C; Parker A; O'Meara S; Avis T; Barthorpe S; Brackenbury L; Buck G; Clements J; Cole J; Dicks E; Edwards K; Forbes S; Gorton M; Gray K; Halliday K; Harrison R; Hills K; Hinton J; Jones D; Kosmidou V; Laman R; Lugg R; Menzies A; Perry J; Petty R; Raine K; Shepherd R; Small A; Solomon H; Stephens Y; Tofts C; Varian J; Webb A; West S; Widaa S; Yates A; Brasseur F; Cooper CS; Flanagan AM; Green A; Knowles M; Leung SY; Looijenga LH; Malkowicz B; Pierotti MA; Teh BT; Yuen ST; Lakhani SR; Easton DF; Weber BL; Goldstraw P; Nicholson AG; Wooster R; Stratton MR; Futreal PA
    Cancer Res; 2005 Sep; 65(17):7591-5. PubMed ID: 16140923
    [TBL] [Abstract][Full Text] [Related]  

  • 74. Frequent loss of heterozygosity at the 19p13.3 locus without LKB1/STK11 mutations in human carcinoma metastases to the brain.
    Sobottka SB; Haase M; Fitze G; Hahn M; Schackert HK; Schackert G
    J Neurooncol; 2000 Sep; 49(3):187-95. PubMed ID: 11212897
    [TBL] [Abstract][Full Text] [Related]  

  • 75. LKB1 gene mutations in Japanese lung cancer patients.
    Onozato R; Kosaka T; Achiwa H; Kuwano H; Takahashi T; Yatabe Y; Mitsudomi T
    Cancer Sci; 2007 Nov; 98(11):1747-51. PubMed ID: 17711506
    [TBL] [Abstract][Full Text] [Related]  

  • 76. The ubiquitin-associated domain of AMPK-related kinases regulates conformation and LKB1-mediated phosphorylation and activation.
    Jaleel M; Villa F; Deak M; Toth R; Prescott AR; Van Aalten DM; Alessi DR
    Biochem J; 2006 Mar; 394(Pt 3):545-55. PubMed ID: 16396636
    [TBL] [Abstract][Full Text] [Related]  

  • 77. The tumor suppressor kinase LKB1: lessons from mouse models.
    Ollila S; Mäkelä TP
    J Mol Cell Biol; 2011 Dec; 3(6):330-40. PubMed ID: 21926085
    [TBL] [Abstract][Full Text] [Related]  

  • 78. Aurora-A-mediated phosphorylation of LKB1 compromises LKB1/AMPK signaling axis to facilitate NSCLC growth and migration.
    Zheng X; Chi J; Zhi J; Zhang H; Yue D; Zhao J; Li D; Li Y; Gao M; Guo J
    Oncogene; 2018 Jan; 37(4):502-511. PubMed ID: 28967900
    [TBL] [Abstract][Full Text] [Related]  

  • 79. Growth and molecular profile of lung cancer cells expressing ectopic LKB1: down-regulation of the phosphatidylinositol 3'-phosphate kinase/PTEN pathway.
    Jimenez AI; Fernandez P; Dominguez O; Dopazo A; Sanchez-Cespedes M
    Cancer Res; 2003 Mar; 63(6):1382-8. PubMed ID: 12649203
    [TBL] [Abstract][Full Text] [Related]  

  • 80. Controlling the master-upstream regulation of the tumor suppressor LKB1.
    Kullmann L; Krahn MP
    Oncogene; 2018 Jun; 37(23):3045-3057. PubMed ID: 29540834
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.