BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

714 related articles for article (PubMed ID: 16828559)

  • 1. Acenaphtho[1,2-b]pyrrole derivatives as new family of intercalators: various DNA binding geometry and interesting antitumor capacity.
    Zhang Z; Yang Y; Zhang D; Wang Y; Qian X; Liu F
    Bioorg Med Chem; 2006 Oct; 14(20):6962-70. PubMed ID: 16828559
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel acenaphtho[1,2-b]pyrrole-carboxylic acid family: synthesis, cytotoxicity, DNA-binding and cell cycle evaluation.
    Xie L; Xiao Y; Wang F; Xu Y; Qian X; Zhang R; Cui J; Liu J
    Bioorg Med Chem; 2009 Nov; 17(21):7615-21. PubMed ID: 19815418
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis, and antitumor evaluation of novel acenaphtho[1,2-b]pyrrole-carboxylic acid esters with amino chain substitution.
    Liu F; Qian X; Cui J; Xiao Y; Zhang R; Li G
    Bioorg Med Chem; 2006 Jul; 14(13):4639-44. PubMed ID: 16516477
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Study on the interaction between 4-(2-diethylamino-ethylamino)-8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carbonitrile and DNA by molecular spectra.
    Zhang Z; Yang Y; Liu F; Qian X; Xu Q
    Int J Biol Macromol; 2006 Feb; 38(1):59-64. PubMed ID: 16448691
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel Bcl-2 inhibitors: Discovery and mechanism study of small organic apoptosis-inducing agents.
    Zhang Z; Jin L; Qian X; Wei M; Wang Y; Wang J; Yang Y; Xu Q; Xu Y; Liu F
    Chembiochem; 2007 Jan; 8(1):113-21. PubMed ID: 17139689
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, and DNA-binding of N-alkyl(anilino)quinazoline derivatives.
    Garofalo A; Goossens L; Baldeyrou B; Lemoine A; Ravez S; Six P; David-Cordonnier MH; Bonte JP; Depreux P; Lansiaux A; Goossens JF
    J Med Chem; 2010 Nov; 53(22):8089-103. PubMed ID: 21033670
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA binding to guide the development of tetrahydroindeno[1,2-b]pyrido[4,3,2-de]quinoline derivatives as cytotoxic agents.
    Catoen-Chackal S; Facompré M; Houssin R; Pommery N; Goossens JF; Colson P; Bailly C; Hénichart JP
    J Med Chem; 2004 Jul; 47(14):3665-73. PubMed ID: 15214793
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Substitution at the F-ring N-imide of the indolocarbazole antitumor drug NB-506 increases the cytotoxicity, DNA binding, and topoisomerase I inhibition activities.
    Bailly C; Qu X; Chaires JB; Colson P; Houssier C; Ohkubo M; Nishimura S; Yoshinari T
    J Med Chem; 1999 Jul; 42(15):2927-35. PubMed ID: 10425102
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, antitumor evaluation and DNA binding studies of novel amidino-benzimidazolyl substituted derivatives of furyl-phenyl- and thienyl-phenyl-acrylates, naphthofurans and naphthothiophenes.
    Hranjec M; Starcević K; Piantanida I; Kralj M; Marjanović M; Hasani M; Westman G; Karminski-Zamola G
    Eur J Med Chem; 2008 Dec; 43(12):2877-90. PubMed ID: 18395297
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DNA binding and biological activity of some platinum(II) intercalating compounds containing methyl-substituted 1,10-phenanthrolines.
    Brodie CR; Collins JG; Aldrich-Wright JR
    Dalton Trans; 2004 Apr; (8):1145-52. PubMed ID: 15252653
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of mono- and bisdihydrodipyridopyrazines and assessment of their DNA binding and cytotoxic properties.
    Blanchard S; Rodriguez I; Tardy C; Baldeyrou B; Bailly C; Colson P; Houssier C; Léonce S; Kraus-Berthier L; Pfeiffer B; Renard P; Pierré A; Caubère P; Guillaumet G
    J Med Chem; 2004 Feb; 47(4):978-87. PubMed ID: 14761199
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel DNA intercalators without basic side chains as efficient antitumor agents: design, synthesis and evaluation of benzo-[c,d]-indol-malononitrile derivatives.
    Li X; Wang Q; Qing Y; Lin Y; Zhang Y; Qian X; Cui J
    Bioorg Med Chem; 2010 May; 18(9):3279-84. PubMed ID: 20385497
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antitumor agents. 3. Design, synthesis, and biological evaluation of new pyridoisoquinolindione and dihydrothienoquinolindione derivatives with potent cytotoxic activity.
    Bolognese A; Correale G; Manfra M; Lavecchia A; Mazzoni O; Novellino E; La Colla P; Sanna G; Loddo R
    J Med Chem; 2004 Feb; 47(4):849-58. PubMed ID: 14761187
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel antitumor agent family of 1H-benzo[c,d]indol-2-one with flexible basic side chains: synthesis and biological evaluation.
    Yin H; Xu Y; Qian X
    Bioorg Med Chem; 2007 Feb; 15(3):1356-62. PubMed ID: 17129733
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DNA binding studies of novel Copper(II) complexes containing L-tryptophan as chiral auxiliary: in vitro antitumor activity of Cu-Sn2 complex in human neuroblastoma cells.
    Chauhan M; Banerjee K; Arjmand F
    Inorg Chem; 2007 Apr; 46(8):3072-82. PubMed ID: 17378549
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and antiproliferative activity of new cytotoxic azanaphthoquinone pyrrolo-annelated derivatives: Part II.
    Shanab K; Schirmer E; Wulz E; Weissenbacher B; Lassnig S; Slanz R; Fösleitner G; Holzer W; Spreitzer H; Schmidt P; Aicher B; Müller G; Günther E
    Bioorg Med Chem Lett; 2011 May; 21(10):3117-21. PubMed ID: 21458262
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Naphthalimide intercalators with chiral amino side chains: effects of chirality on DNA binding, photodamage and antitumor cytotoxicity.
    Yang Q; Yang P; Qian X; Tong L
    Bioorg Med Chem Lett; 2008 Dec; 18(23):6210-3. PubMed ID: 18930399
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 5-Non-amino aromatic substituted naphthalimides as potential antitumor agents: Synthesis via Suzuki reaction, antiproliferative activity, and DNA-binding behavior.
    Xie L; Cui J; Qian X; Xu Y; Liu J; Xu R
    Bioorg Med Chem; 2011 Jan; 19(2):961-7. PubMed ID: 21208805
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological evaluation of novel cytotoxic azanaphthoquinone annelated pyrrolo oximes.
    Shanab K; Pongprom N; Wulz E; Holzer W; Spreitzer H; Schmidt P; Aicher B; Müller G; Günther E
    Bioorg Med Chem Lett; 2007 Nov; 17(22):6091-5. PubMed ID: 17904839
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA binding and anticancer activity of naphthalimides with 4-hydroxyl-alkylamine side chains at different lengths.
    Wang K; Wang Y; Yan X; Chen H; Ma G; Zhang P; Li J; Li X; Zhang J
    Bioorg Med Chem Lett; 2012 Jan; 22(2):937-41. PubMed ID: 22200595
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 36.