73 related articles for article (PubMed ID: 16828865)
1. Atiprimod blocks phosphorylation of JAK-STAT and inhibits proliferation of acute myeloid leukemia (AML) cells.
Faderl S; Ferrajoli A; Harris D; Van Q; Kantarjian HM; Estrov Z
Leuk Res; 2007 Jan; 31(1):91-5. PubMed ID: 16828865
[TBL] [Abstract][Full Text] [Related]
2. WP1066 disrupts Janus kinase-2 and induces caspase-dependent apoptosis in acute myelogenous leukemia cells.
Ferrajoli A; Faderl S; Van Q; Koch P; Harris D; Liu Z; Hazan-Halevy I; Wang Y; Kantarjian HM; Priebe W; Estrov Z
Cancer Res; 2007 Dec; 67(23):11291-9. PubMed ID: 18056455
[TBL] [Abstract][Full Text] [Related]
3. 8-benzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid (SD-1008), a novel janus kinase 2 inhibitor, increases chemotherapy sensitivity in human ovarian cancer cells.
Duan Z; Bradner J; Greenberg E; Mazitschek R; Foster R; Mahoney J; Seiden MV
Mol Pharmacol; 2007 Nov; 72(5):1137-45. PubMed ID: 17675586
[TBL] [Abstract][Full Text] [Related]
4. Atiprimod is an inhibitor of cancer cell proliferation and angiogenesis.
Shailubhai K; Dheer S; Picker D; Kaur G; Sausville EA; Jacob GS
J Exp Ther Oncol; 2004 Dec; 4(4):267-79. PubMed ID: 15844657
[TBL] [Abstract][Full Text] [Related]
5. Preclinical characterization of atiprimod, a novel JAK2 AND JAK3 inhibitor.
Quintás-Cardama A; Manshouri T; Estrov Z; Harris D; Zhang Y; Gaikwad A; Kantarjian HM; Verstovsek S
Invest New Drugs; 2011 Oct; 29(5):818-26. PubMed ID: 20372971
[TBL] [Abstract][Full Text] [Related]
6. WP-1034, a novel JAK-STAT inhibitor, with proapoptotic and antileukemic activity in acute myeloid leukemia (AML).
Faderl S; Ferrajoli A; Harris D; Van Q; Priebe W; Estrov Z
Anticancer Res; 2005; 25(3B):1841-50. PubMed ID: 16158916
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of Flt3-activating mutations does not prevent constitutive activation of ERK/Akt/STAT pathways in some AML cells: a possible cause for the limited effectiveness of monotherapy with small-molecule inhibitors.
Siendones E; Barbarroja N; Torres LA; Buendía P; Velasco F; Dorado G; Torres A; López-Pedrera C
Hematol Oncol; 2007 Mar; 25(1):30-7. PubMed ID: 17128418
[TBL] [Abstract][Full Text] [Related]
8. [Specific function of STAT5 in regulation of proliferation of chronic leukemia K562 cells: inhibitory effect of WHI-P131].
Mitiushova EV; Aksenov ND; Marakhova II
Tsitologiia; 2010; 52(2):184-90. PubMed ID: 20352702
[TBL] [Abstract][Full Text] [Related]
9. Atiprimod blocks STAT3 phosphorylation and induces apoptosis in multiple myeloma cells.
Amit-Vazina M; Shishodia S; Harris D; Van Q; Wang M; Weber D; Alexanian R; Talpaz M; Aggarwal BB; Estrov Z
Br J Cancer; 2005 Jul; 93(1):70-80. PubMed ID: 15970928
[TBL] [Abstract][Full Text] [Related]
10. Licochalcone A is a potent inhibitor of TEL-Jak2-mediated transformation through the specific inhibition of Stat3 activation.
Funakoshi-Tago M; Tago K; Nishizawa C; Takahashi K; Mashino T; Iwata S; Inoue H; Sonoda Y; Kasahara T
Biochem Pharmacol; 2008 Dec; 76(12):1681-93. PubMed ID: 18848530
[TBL] [Abstract][Full Text] [Related]
11. Cell density dependent increase of constitutive signal transducers and activators of transcription 3 activity in melanoma cells is mediated by Janus kinases.
Kreis S; Munz GA; Haan S; Heinrich PC; Behrmann I
Mol Cancer Res; 2007 Dec; 5(12):1331-41. PubMed ID: 18171991
[TBL] [Abstract][Full Text] [Related]
12. WP1066, a novel JAK2 inhibitor, suppresses proliferation and induces apoptosis in erythroid human cells carrying the JAK2 V617F mutation.
Verstovsek S; Manshouri T; Quintás-Cardama A; Harris D; Cortes J; Giles FJ; Kantarjian H; Priebe W; Estrov Z
Clin Cancer Res; 2008 Feb; 14(3):788-96. PubMed ID: 18245540
[TBL] [Abstract][Full Text] [Related]
13. Signal transduction pathways of GM-CSF in neural cell lines.
Choi JK; Choi BH; Ha Y; Park H; Yoon SH; Park HC; Park SR
Neurosci Lett; 2007 Jun; 420(3):217-22. PubMed ID: 17556097
[TBL] [Abstract][Full Text] [Related]
14. Suppression of IL-1beta expression by the Jak 2 inhibitor AG490 in cerulein-stimulated pancreatic acinar cells.
Yu JH; Kim KH; Kim H
Biochem Pharmacol; 2006 Nov; 72(11):1555-62. PubMed ID: 16934228
[TBL] [Abstract][Full Text] [Related]
15. Pyridone 6, a pan-Janus-activated kinase inhibitor, induces growth inhibition of multiple myeloma cells.
Pedranzini L; Dechow T; Berishaj M; Comenzo R; Zhou P; Azare J; Bornmann W; Bromberg J
Cancer Res; 2006 Oct; 66(19):9714-21. PubMed ID: 17018630
[TBL] [Abstract][Full Text] [Related]
16. Contribution of STAT3 to the activation of survivin by GM-CSF in CD34+ cell lines.
Gu L; Chiang KY; Zhu N; Findley HW; Zhou M
Exp Hematol; 2007 Jun; 35(6):957-66. PubMed ID: 17533050
[TBL] [Abstract][Full Text] [Related]
17. Combined inhibition of integrin linked kinase and FMS-like tyrosine kinase 3 is cytotoxic to acute myeloid leukemia progenitor cells.
Muranyi AL; Dedhar S; Hogge DE
Exp Hematol; 2009 Apr; 37(4):450-60. PubMed ID: 19302919
[TBL] [Abstract][Full Text] [Related]
18. t(8;21) acute myeloid leukaemia cells are dependent on vascular endothelial growth factor (VEGF)/VEGF receptor type2 pathway and phosphorylation of Akt.
Imai N; Shikami M; Miwa H; Suganuma K; Hiramatsu A; Watarai M; Satoh A; Itoh M; Imamura A; Mihara H; Nitta M
Br J Haematol; 2006 Dec; 135(5):673-82. PubMed ID: 17107349
[TBL] [Abstract][Full Text] [Related]
19. Role of altered growth factor receptor-mediated JAK2 signaling in growth and maintenance of human acute myeloid leukemia stem cells.
Cook AM; Li L; Ho Y; Lin A; Li L; Stein A; Forman S; Perrotti D; Jove R; Bhatia R
Blood; 2014 May; 123(18):2826-37. PubMed ID: 24668492
[TBL] [Abstract][Full Text] [Related]
20. Constitutively activated FLT3 phosphorylates BAD partially through pim-1.
Kim KT; Levis M; Small D
Br J Haematol; 2006 Sep; 134(5):500-9. PubMed ID: 16869825
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
