390 related articles for article (PubMed ID: 16829959)
21. MLL core components give the green light to histone methylation.
Crawford BD; Hess JL
ACS Chem Biol; 2006 Sep; 1(8):495-8. PubMed ID: 17168535
[TBL] [Abstract][Full Text] [Related]
22. Mixed lineage leukemia: a structure-function perspective of the MLL1 protein.
Cosgrove MS; Patel A
FEBS J; 2010 Apr; 277(8):1832-42. PubMed ID: 20236310
[TBL] [Abstract][Full Text] [Related]
23. A conserved arginine-containing motif crucial for the assembly and enzymatic activity of the mixed lineage leukemia protein-1 core complex.
Patel A; Vought VE; Dharmarajan V; Cosgrove MS
J Biol Chem; 2008 Nov; 283(47):32162-75. PubMed ID: 18829457
[TBL] [Abstract][Full Text] [Related]
24. Unique Role of the WD-40 Repeat Protein 5 (WDR5) Subunit within the Mixed Lineage Leukemia 3 (MLL3) Histone Methyltransferase Complex.
Shinsky SA; Cosgrove MS
J Biol Chem; 2015 Oct; 290(43):25819-33. PubMed ID: 26324722
[TBL] [Abstract][Full Text] [Related]
25. The Development of Inhibitors Targeting the Mixed Lineage Leukemia 1 (MLL1)-WD Repeat Domain 5 Protein (WDR5) Protein- Protein Interaction.
Ye X; Chen G; Jin J; Zhang B; Wang Y; Cai Z; Ye F
Curr Med Chem; 2020; 27(33):5530-5542. PubMed ID: 31132972
[TBL] [Abstract][Full Text] [Related]
26. Analysis of the binding of mixed lineage leukemia 1 (MLL1) and histone 3 peptides to WD repeat domain 5 (WDR5) for the design of inhibitors of the MLL1-WDR5 interaction.
Karatas H; Townsend EC; Bernard D; Dou Y; Wang S
J Med Chem; 2010 Jul; 53(14):5179-85. PubMed ID: 20575550
[TBL] [Abstract][Full Text] [Related]
27. CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation.
Higa LA; Wu M; Ye T; Kobayashi R; Sun H; Zhang H
Nat Cell Biol; 2006 Nov; 8(11):1277-83. PubMed ID: 17041588
[TBL] [Abstract][Full Text] [Related]
28. Histone H3K27 trimethylation inhibits H3 binding and function of SET1-like H3K4 methyltransferase complexes.
Kim DH; Tang Z; Shimada M; Fierz B; Houck-Loomis B; Bar-Dagen M; Lee S; Lee SK; Muir TW; Roeder RG; Lee JW
Mol Cell Biol; 2013 Dec; 33(24):4936-46. PubMed ID: 24126056
[TBL] [Abstract][Full Text] [Related]
29. The internal interaction in RBBP5 regulates assembly and activity of MLL1 methyltransferase complex.
Han J; Li T; Li Y; Li M; Wang X; Peng C; Su C; Li N; Li Y; Xu Y; Chen Y
Nucleic Acids Res; 2019 Nov; 47(19):10426-10438. PubMed ID: 31544921
[TBL] [Abstract][Full Text] [Related]
30. Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II.
Wang P; Lin C; Smith ER; Guo H; Sanderson BW; Wu M; Gogol M; Alexander T; Seidel C; Wiedemann LM; Ge K; Krumlauf R; Shilatifard A
Mol Cell Biol; 2009 Nov; 29(22):6074-85. PubMed ID: 19703992
[TBL] [Abstract][Full Text] [Related]
31. A non-active-site SET domain surface crucial for the interaction of MLL1 and the RbBP5/Ash2L heterodimer within MLL family core complexes.
Shinsky SA; Hu M; Vought VE; Ng SB; Bamshad MJ; Shendure J; Cosgrove MS
J Mol Biol; 2014 Jun; 426(12):2283-99. PubMed ID: 24680668
[TBL] [Abstract][Full Text] [Related]
32. Molecular regulation of H3K4 trimethylation by ASH2L, a shared subunit of MLL complexes.
Steward MM; Lee JS; O'Donovan A; Wyatt M; Bernstein BE; Shilatifard A
Nat Struct Mol Biol; 2006 Sep; 13(9):852-4. PubMed ID: 16892064
[TBL] [Abstract][Full Text] [Related]
33. A role for WDR5 in integrating threonine 11 phosphorylation to lysine 4 methylation on histone H3 during androgen signaling and in prostate cancer.
Kim JY; Banerjee T; Vinckevicius A; Luo Q; Parker JB; Baker MR; Radhakrishnan I; Wei JJ; Barish GD; Chakravarti D
Mol Cell; 2014 May; 54(4):613-25. PubMed ID: 24793694
[TBL] [Abstract][Full Text] [Related]
34. PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation.
Hyllus D; Stein C; Schnabel K; Schiltz E; Imhof A; Dou Y; Hsieh J; Bauer UM
Genes Dev; 2007 Dec; 21(24):3369-80. PubMed ID: 18079182
[TBL] [Abstract][Full Text] [Related]
35. Structure-based design and synthesis of small molecular inhibitors disturbing the interaction of MLL1-WDR5.
Li DD; Chen WL; Xu XL; Jiang F; Wang L; Xie YY; Zhang XJ; Guo XK; You QD; Sun HP
Eur J Med Chem; 2016 Aug; 118():1-8. PubMed ID: 27116709
[TBL] [Abstract][Full Text] [Related]
36. Set1/MLL complex is indispensable for the transcriptional ability of heat shock transcription factor 2.
Hayashida N
Biochem Biophys Res Commun; 2015 Nov; 467(4):805-12. PubMed ID: 26478434
[TBL] [Abstract][Full Text] [Related]
37. High-affinity small molecular blockers of mixed lineage leukemia 1 (MLL1)-WDR5 interaction inhibit MLL1 complex H3K4 methyltransferase activity.
Li DD; Chen WL; Wang ZH; Xie YY; Xu XL; Jiang ZY; Zhang XJ; You QD; Guo XK
Eur J Med Chem; 2016 Nov; 124():480-489. PubMed ID: 27598236
[TBL] [Abstract][Full Text] [Related]
38. Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A.
Huang Y; Fang J; Bedford MT; Zhang Y; Xu RM
Science; 2006 May; 312(5774):748-51. PubMed ID: 16601153
[TBL] [Abstract][Full Text] [Related]
39. MLL1/WDR5 complex in leukemogenesis and epigenetic regulation.
Wu M; Shu HB
Chin J Cancer; 2011 Apr; 30(4):240-6. PubMed ID: 21439245
[TBL] [Abstract][Full Text] [Related]
40. The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases.
Zhang P; Lee H; Brunzelle JS; Couture JF
Nucleic Acids Res; 2012 May; 40(9):4237-46. PubMed ID: 22266653
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]