These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

119 related articles for article (PubMed ID: 1683214)

  • 1. Synergistic inhibition of human immunodeficiency virus type 1 (HIV-1) replication in vitro by 1-[(2-hydroxyethoxy)methyl]-6-phenylthiothymine (HEPT) and recombinant alpha interferon.
    Ito M; Baba M; Shigeta S; De Clercq E; Walker RT; Tanaka H; Miyasaka T
    Antiviral Res; 1991 May; 15(4):323-30. PubMed ID: 1683214
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Anti-human immunodeficiency virus type 1 activities and pharmacokinetics of novel 6-substituted acyclouridine derivatives.
    Baba M; De Clercq E; Iida S; Tanaka H; Nitta I; Ubasawa M; Takashima H; Sekiya K; Umezu K; Nakashima H
    Antimicrob Agents Chemother; 1990 Dec; 34(12):2358-63. PubMed ID: 2088190
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Highly specific inhibition of human immunodeficiency virus type 1 by a novel 6-substituted acyclouridine derivative.
    Baba M; Tanaka H; De Clercq E; Pauwels R; Balzarini J; Schols D; Nakashima H; Perno CF; Walker RT; Miyasaka T
    Biochem Biophys Res Commun; 1989 Dec; 165(3):1375-81. PubMed ID: 2575380
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effect of human serum on the in vitro anti-HIV-1 activity of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) derivatives as related to their lipophilicity and serum protein binding.
    Baba M; Yuasa S; Niwa T; Yamamoto M; Yabuuchi S; Takashima H; Ubasawa M; Tanaka H; Miyasaka T; Walker RT
    Biochem Pharmacol; 1993 Jun; 45(12):2507-12. PubMed ID: 8328988
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-activity relationships of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine analogues: effect of substitutions at the C-6 phenyl ring and at the C-5 position on anti-HIV-1 activity.
    Tanaka H; Takashima H; Ubasawa M; Sekiya K; Nitta I; Baba M; Shigeta S; Walker RT; De Clercq E; Miyasaka T
    J Med Chem; 1992 Jan; 35(2):337-45. PubMed ID: 1732552
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synergistic inhibition of human immunodeficiency virus type 1 replication by 5-ethyl-1-ethoxymethyl-6-(phenylthio)uracil (E-EPU) and azidothymidine in vitro.
    Baba M; Ito M; Shigeta S; Tanaka H; Miyasaka T; Ubasawa M; Umezu K; Walker RT; De Clercq E
    Antimicrob Agents Chemother; 1991 Jul; 35(7):1430-3. PubMed ID: 1929304
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and antiviral activity of deoxy analogs of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) as potent and selective anti-HIV-1 agents.
    Tanaka H; Takashima H; Ubasawa M; Sekiya K; Nitta I; Baba M; Shigeta S; Walker RT; De Clercq E; Miyasaka T
    J Med Chem; 1992 Dec; 35(25):4713-9. PubMed ID: 1469700
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Chemotherapy of the acquired immune deficiency syndrome (AIDS): non-nucleoside inhibitors of the human immunodeficiency virus type 1 reverse transcriptase.
    De Clercq E
    Int J Immunopharmacol; 1991; 13 Suppl 1():83-9. PubMed ID: 1726686
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Kinetics of inhibition of endogenous human immunodeficiency virus type 1 reverse transcription by 2',3'-dideoxynucleoside 5'-triphosphate, tetrahydroimidazo-[4,5,1-jk][1,4]-benzodiazepin-2(1H)-thion e, and 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives.
    Debyser Z; Vandamme AM; Pauwels R; Baba M; Desmyter J; De Clercq E
    J Biol Chem; 1992 Jun; 267(17):11769-76. PubMed ID: 1376311
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Three-drug synergistic inhibition of HIV-1 replication in vitro by zidovudine, recombinant soluble CD4, and recombinant interferon-alpha A.
    Johnson VA; Barlow MA; Merrill DP; Chou TC; Hirsch MS
    J Infect Dis; 1990 Jun; 161(6):1059-67. PubMed ID: 2345291
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Highly potent and selective inhibition of human immunodeficiency virus type 1 by a novel series of 6-substituted acyclouridine derivatives.
    Baba M; De Clercq E; Tanaka H; Ubasawa M; Takashima H; Sekiya K; Nitta I; Umezu K; Walker RT; Mori S
    Mol Pharmacol; 1991 Jun; 39(6):805-10. PubMed ID: 1711148
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Potent and selective inhibition of human immunodeficiency virus type 1 (HIV-1) by 5-ethyl-6-phenylthiouracil derivatives through their interaction with the HIV-1 reverse transcriptase.
    Baba M; De Clercq E; Tanaka H; Ubasawa M; Takashima H; Sekiya K; Nitta I; Umezu K; Nakashima H; Mori S
    Proc Natl Acad Sci U S A; 1991 Mar; 88(6):2356-60. PubMed ID: 1706522
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vitro inhibition of human immunodeficiency virus type 1 by a combination of delavirdine (U-90152) with protease inhibitor U-75875 or interferon-alpha.
    Pagano PJ; Chong KT
    J Infect Dis; 1995 Jan; 171(1):61-7. PubMed ID: 7528253
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human immunodeficiency virus type 1 drug-resistance patterns with different 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives.
    Balzarini J; Karlsson A; De Clercq E
    Mol Pharmacol; 1993 Oct; 44(4):694-701. PubMed ID: 7694068
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nevirapine synergistically inhibits HIV-1 replication in combination with zidovudine, interferon or CD4 immunoadhesin.
    Koup RA; Brewster F; Grob P; Sullivan JL
    AIDS; 1993 Sep; 7(9):1181-4. PubMed ID: 7692883
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Resistance to 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives is generated by mutations at multiple sites in the HIV-1 reverse transcriptase.
    Buckheit RW; Fliakas-Boltz V; Yeagy-Bargo S; Weislow O; Mayers DL; Boyer PL; Hughes SH; Pan BC; Chu SH; Bader JP
    Virology; 1995 Jun; 210(1):186-93. PubMed ID: 7540784
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and anti-HIV activity of 2-, 3-, and 4-substituted analogues of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT).
    Tanaka H; Baba M; Ubasawa M; Takashima H; Sekiya K; Nitta I; Shigeta S; Walker RT; De Clercq E; Miyasaka T
    J Med Chem; 1991 Apr; 34(4):1394-9. PubMed ID: 2016715
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synergistic inhibition of human immunodeficiency virus in vitro by azidothymidine and recombinant alpha A interferon.
    Hartshorn KL; Vogt MW; Chou TC; Blumberg RS; Byington R; Schooley RT; Hirsch MS
    Antimicrob Agents Chemother; 1987 Feb; 31(2):168-72. PubMed ID: 3471180
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In vitro replication of HIV-1 in naturally infected CD4+ T cells is inhibited by rIFN alpha 2 and by a soluble factor secreted by activated CD8+ T cells, but not by rIFN beta, rIFN gamma, or recombinant tumor necrosis factor-alpha.
    Brinchmann JE; Gaudernack G; Vartdal F
    J Acquir Immune Defic Syndr (1988); 1991; 4(5):480-8. PubMed ID: 1673156
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel lead for specific anti-HIV-1 agents: 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine.
    Miyasaka T; Tanaka H; Baba M; Hayakawa H; Walker RT; Balzarini J; De Clercq E
    J Med Chem; 1989 Dec; 32(12):2507-9. PubMed ID: 2479745
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 6.