BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

469 related articles for article (PubMed ID: 16837456)

  • 1. PAR4, but not PAR1, signals human platelet aggregation via Ca2+ mobilization and synergistic P2Y12 receptor activation.
    Holinstat M; Voss B; Bilodeau ML; McLaughlin JN; Cleator J; Hamm HE
    J Biol Chem; 2006 Sep; 281(36):26665-74. PubMed ID: 16837456
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The ATP-gated P2X1 receptor plays a pivotal role in activation of aspirin-treated platelets by thrombin and epinephrine.
    Grenegård M; Vretenbrant-Oberg K; Nylander M; Désilets S; Lindström EG; Larsson A; Ramström I; Ramström S; Lindahl TL
    J Biol Chem; 2008 Jul; 283(27):18493-504. PubMed ID: 18480058
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Protease-activated receptor-induced Akt activation--regulation and possible function.
    Reséndiz JC; Kroll MH; Lassila R
    J Thromb Haemost; 2007 Dec; 5(12):2484-93. PubMed ID: 17883592
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Protease-activated receptors 1 and 4 do not stimulate G(i) signaling pathways in the absence of secreted ADP and cause human platelet aggregation independently of G(i) signaling.
    Kim S; Foster C; Lecchi A; Quinton TM; Prosser DM; Jin J; Cattaneo M; Kunapuli SP
    Blood; 2002 May; 99(10):3629-36. PubMed ID: 11986217
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Protease-activating receptor-4 induces full platelet spreading on a fibrinogen matrix: involvement of ERK2 and p38 and Ca2+ mobilization.
    Mazharian A; Roger S; Berrou E; Adam F; Kauskot A; Nurden P; Jandrot-Perrus M; Bryckaert M
    J Biol Chem; 2007 Feb; 282(8):5478-87. PubMed ID: 17200114
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Protease-activated receptor-4 (PAR4) variant influences on platelet reactivity induced by PAR4-activating peptide through altered Ca
    Morikawa Y; Kato H; Kashiwagi H; Nishiura N; Akuta K; Honda S; Kanakura Y; Tomiyama Y
    Thromb Res; 2018 Feb; 162():44-52. PubMed ID: 29289806
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The roles and mechanisms of PAR4 and P2Y12/phosphatidylinositol 3-kinase pathway in maintaining thrombin-induced platelet aggregation.
    Wu CC; Wu SY; Liao CY; Teng CM; Wu YC; Kuo SC
    Br J Pharmacol; 2010 Oct; 161(3):643-58. PubMed ID: 20880402
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biphasic kinetics of activation and signaling for PAR1 and PAR4 thrombin receptors in platelets.
    Covic L; Gresser AL; Kuliopulos A
    Biochemistry; 2000 May; 39(18):5458-67. PubMed ID: 10820018
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The protease-activated receptor 4 Ala120Thr variant alters platelet responsiveness to low-dose thrombin and protease-activated receptor 4 desensitization, and is blocked by non-competitive P2Y
    Whitley MJ; Henke DM; Ghazi A; Nieman M; Stoller M; Simon LM; Chen E; Vesci J; Holinstat M; McKenzie SE; Shaw CA; Edelstein LC; Bray PF
    J Thromb Haemost; 2018 Dec; 16(12):2501-2514. PubMed ID: 30347494
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Antithrombotic effects of PAR1 and PAR4 antagonists evaluated under flow and static conditions.
    Hosokawa K; Ohnishi T; Miura N; Sameshima H; Koide T; Tanaka KA; Maruyama I
    Thromb Res; 2014 Jan; 133(1):66-72. PubMed ID: 24268424
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protease-activated receptors differentially regulate human platelet activation through a phosphatidic acid-dependent pathway.
    Holinstat M; Voss B; Bilodeau ML; Hamm HE
    Mol Pharmacol; 2007 Mar; 71(3):686-94. PubMed ID: 17151288
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PAR1 antagonists inhibit thrombin-induced platelet activation whilst leaving the PAR4-mediated response intact.
    Judge HM; Jennings LK; Moliterno DJ; Hord E; Ecob R; Tricoci P; Rorick T; Kotha J; Storey RF
    Platelets; 2015; 26(3):236-42. PubMed ID: 24750101
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Blocking the protease-activated receptor 1-4 heterodimer in platelet-mediated thrombosis.
    Leger AJ; Jacques SL; Badar J; Kaneider NC; Derian CK; Andrade-Gordon P; Covic L; Kuliopulos A
    Circulation; 2006 Mar; 113(9):1244-54. PubMed ID: 16505172
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Thrombin-induced platelet PAR4 activation: role of glycoprotein Ib and ADP.
    Adam F; Verbeuren TJ; Fauchère JL; Guillin MC; Jandrot-Perrus M
    J Thromb Haemost; 2003 Apr; 1(4):798-804. PubMed ID: 12871418
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Contributions of Protease-Activated Receptors PAR1 and PAR4 to Thrombin-Induced GPIIbIIIa Activation in Human Platelets.
    Duvernay MT; Temple KJ; Maeng JG; Blobaum AL; Stauffer SR; Lindsley CW; Hamm HE
    Mol Pharmacol; 2017 Jan; 91(1):39-47. PubMed ID: 27784794
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Glycoprotein IIb/IIIa and P2Y12 receptor antagonists yield additive inhibition of platelet aggregation, granule secretion, soluble CD40L release and procoagulant responses.
    Judge HM; Buckland RJ; Holgate CE; Storey RF
    Platelets; 2005 Nov; 16(7):398-407. PubMed ID: 16236601
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Role of adenosine diphosphate in the course of thrombin signal transmission].
    Han Y; Lu XX; Wang ZY; Dai L; Shen WH; Wu DP; Ruan CG
    Zhonghua Yi Xue Za Zhi; 2006 Dec; 86(46):3299-301. PubMed ID: 17313817
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of protease-activated receptor 4 impairs platelet procoagulant activity during thrombus formation in human blood.
    French SL; Arthur JF; Lee H; Nesbitt WS; Andrews RK; Gardiner EE; Hamilton JR
    J Thromb Haemost; 2016 Aug; 14(8):1642-54. PubMed ID: 26878340
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin.
    Kahn ML; Nakanishi-Matsui M; Shapiro MJ; Ishihara H; Coughlin SR
    J Clin Invest; 1999 Mar; 103(6):879-87. PubMed ID: 10079109
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanism of race-dependent platelet activation through the protease-activated receptor-4 and Gq signaling axis.
    Tourdot BE; Conaway S; Niisuke K; Edelstein LC; Bray PF; Holinstat M
    Arterioscler Thromb Vasc Biol; 2014 Dec; 34(12):2644-50. PubMed ID: 25278289
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.