256 related articles for article (PubMed ID: 16846237)
1. The calcium channel blockers, 1,4-dihydropyridines, are substrates of the multidrug resistance-linked ABC drug transporter, ABCG2.
Shukla S; Robey RW; Bates SE; Ambudkar SV
Biochemistry; 2006 Jul; 45(29):8940-51. PubMed ID: 16846237
[TBL] [Abstract][Full Text] [Related]
2. Modulation of the function of the multidrug resistance-linked ATP-binding cassette transporter ABCG2 by the cancer chemopreventive agent curcumin.
Chearwae W; Shukla S; Limtrakul P; Ambudkar SV
Mol Cancer Ther; 2006 Aug; 5(8):1995-2006. PubMed ID: 16928820
[TBL] [Abstract][Full Text] [Related]
3. Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin.
Limtrakul P; Chearwae W; Shukla S; Phisalphong C; Ambudkar SV
Mol Cell Biochem; 2007 Feb; 296(1-2):85-95. PubMed ID: 16960658
[TBL] [Abstract][Full Text] [Related]
4. BCRP transports dipyridamole and is inhibited by calcium channel blockers.
Zhang Y; Gupta A; Wang H; Zhou L; Vethanayagam RR; Unadkat JD; Mao Q
Pharm Res; 2005 Dec; 22(12):2023-34. PubMed ID: 16247709
[TBL] [Abstract][Full Text] [Related]
5. Effects of dihydropyridines and pyridines on multidrug resistance mediated by breast cancer resistance protein: in vitro and in vivo studies.
Zhou XF; Yang X; Wang Q; Coburn RA; Morris ME
Drug Metab Dispos; 2005 Aug; 33(8):1220-8. PubMed ID: 15908473
[TBL] [Abstract][Full Text] [Related]
6. Erlotinib (Tarceva, OSI-774) antagonizes ATP-binding cassette subfamily B member 1 and ATP-binding cassette subfamily G member 2-mediated drug resistance.
Shi Z; Peng XX; Kim IW; Shukla S; Si QS; Robey RW; Bates SE; Shen T; Ashby CR; Fu LW; Ambudkar SV; Chen ZS
Cancer Res; 2007 Nov; 67(22):11012-20. PubMed ID: 18006847
[TBL] [Abstract][Full Text] [Related]
7. Synthetic Analogs of Curcumin Modulate the Function of Multidrug Resistance-Linked ATP-Binding Cassette Transporter ABCG2.
Murakami M; Ohnuma S; Fukuda M; Chufan EE; Kudoh K; Kanehara K; Sugisawa N; Ishida M; Naitoh T; Shibata H; Iwabuchi Y; Ambudkar SV; Unno M
Drug Metab Dispos; 2017 Nov; 45(11):1166-1177. PubMed ID: 28904007
[TBL] [Abstract][Full Text] [Related]
8. OSI-930 analogues as novel reversal agents for ABCG2-mediated multidrug resistance.
Kuang YH; Patel JP; Sodani K; Wu CP; Liao LQ; Patel A; Tiwari AK; Dai CL; Chen X; Fu LW; Ambudkar SV; Korlipara VL; Chen ZS
Biochem Pharmacol; 2012 Sep; 84(6):766-74. PubMed ID: 22750060
[TBL] [Abstract][Full Text] [Related]
9. Sildenafil reverses ABCB1- and ABCG2-mediated chemotherapeutic drug resistance.
Shi Z; Tiwari AK; Shukla S; Robey RW; Singh S; Kim IW; Bates SE; Peng X; Abraham I; Ambudkar SV; Talele TT; Fu LW; Chen ZS
Cancer Res; 2011 Apr; 71(8):3029-41. PubMed ID: 21402712
[TBL] [Abstract][Full Text] [Related]
10. The naphthoquinones, vitamin K3 and its structural analogue plumbagin, are substrates of the multidrug resistance linked ATP binding cassette drug transporter ABCG2.
Shukla S; Wu CP; Nandigama K; Ambudkar SV
Mol Cancer Ther; 2007 Dec; 6(12 Pt 1):3279-86. PubMed ID: 18065489
[TBL] [Abstract][Full Text] [Related]
11. Loss of cyclosporin and azidopine binding are associated with altered ATPase activity by a mutant P-glycoprotein with deleted phe(335).
Chen KG; Lacayo NJ; Durán GE; Cohen D; Sikic BI
Mol Pharmacol; 2000 Apr; 57(4):769-77. PubMed ID: 10727524
[TBL] [Abstract][Full Text] [Related]
12. Becatecarin (rebeccamycin analog, NSC 655649) is a transport substrate and induces expression of the ATP-binding cassette transporter, ABCG2, in lung carcinoma cells.
Robey RW; Obrzut T; Shukla S; Polgar O; Macalou S; Bahr JC; Di Pietro A; Ambudkar SV; Bates SE
Cancer Chemother Pharmacol; 2009 Aug; 64(3):575-83. PubMed ID: 19132374
[TBL] [Abstract][Full Text] [Related]
13. Multidrug resistance transporter P-glycoprotein has distinct but interacting binding sites for cytotoxic drugs and reversing agents.
Pascaud C; Garrigos M; Orlowski S
Biochem J; 1998 Jul; 333 ( Pt 2)(Pt 2):351-8. PubMed ID: 9657975
[TBL] [Abstract][Full Text] [Related]
14. Differential sensitivities of the human ATP-binding cassette transporters ABCG2 and P-glycoprotein to cyclosporin A.
Ejendal KF; Hrycyna CA
Mol Pharmacol; 2005 Mar; 67(3):902-11. PubMed ID: 15598974
[TBL] [Abstract][Full Text] [Related]
15. Celastraceae sesquiterpenes as a new class of modulators that bind specifically to human P-glycoprotein and reverse cellular multidrug resistance.
Muñoz-Martínez F; Lu P; Cortés-Selva F; Pérez-Victoria JM; Jiménez IA; Ravelo AG; Sharom FJ; Gamarro F; Castanys S
Cancer Res; 2004 Oct; 64(19):7130-8. PubMed ID: 15466210
[TBL] [Abstract][Full Text] [Related]
16. Curcumin inhibits the activity of ABCG2/BCRP1, a multidrug resistance-linked ABC drug transporter in mice.
Shukla S; Zaher H; Hartz A; Bauer B; Ware JA; Ambudkar SV
Pharm Res; 2009 Feb; 26(2):480-7. PubMed ID: 18841445
[TBL] [Abstract][Full Text] [Related]
17. The molecular basis of the action of disulfiram as a modulator of the multidrug resistance-linked ATP binding cassette transporters MDR1 (ABCB1) and MRP1 (ABCC1).
Sauna ZE; Peng XH; Nandigama K; Tekle S; Ambudkar SV
Mol Pharmacol; 2004 Mar; 65(3):675-84. PubMed ID: 14978246
[TBL] [Abstract][Full Text] [Related]
18. Effect of Walker A mutation (K86M) on oligomerization and surface targeting of the multidrug resistance transporter ABCG2.
Henriksen U; Gether U; Litman T
J Cell Sci; 2005 Apr; 118(Pt 7):1417-26. PubMed ID: 15769853
[TBL] [Abstract][Full Text] [Related]
19. The nature of amino acid 482 of human ABCG2 affects substrate transport and ATP hydrolysis but not substrate binding.
Ejendal KF; Diop NK; Schweiger LC; Hrycyna CA
Protein Sci; 2006 Jul; 15(7):1597-607. PubMed ID: 16815914
[TBL] [Abstract][Full Text] [Related]
20. Characterization of drug transport, ATP hydrolysis, and nucleotide trapping by the human ABCG2 multidrug transporter. Modulation of substrate specificity by a point mutation.
Ozvegy C; Váradi A; Sarkadi B
J Biol Chem; 2002 Dec; 277(50):47980-90. PubMed ID: 12374800
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
