298 related articles for article (PubMed ID: 16847058)
1. Roles for UDP-GlcNAc 2-epimerase/ManNAc 6-kinase outside of sialic acid biosynthesis: modulation of sialyltransferase and BiP expression, GM3 and GD3 biosynthesis, proliferation, and apoptosis, and ERK1/2 phosphorylation.
Wang Z; Sun Z; Li AV; Yarema KJ
J Biol Chem; 2006 Sep; 281(37):27016-28. PubMed ID: 16847058
[TBL] [Abstract][Full Text] [Related]
2. Ganglioside GM3 levels are altered in a mouse model of HIBM: GM3 as a cellular marker of the disease.
Paccalet T; Coulombe Z; Tremblay JP
PLoS One; 2010 Apr; 5(4):e10055. PubMed ID: 20383336
[TBL] [Abstract][Full Text] [Related]
3. Regulation and pathophysiological implications of UDP-GlcNAc 2-epimerase/ManNAc kinase (GNE) as the key enzyme of sialic acid biosynthesis.
Reinke SO; Lehmer G; Hinderlich S; Reutter W
Biol Chem; 2009 Jul; 390(7):591-9. PubMed ID: 19426133
[TBL] [Abstract][Full Text] [Related]
4. Lec3 Chinese hamster ovary mutants lack UDP-N-acetylglucosamine 2-epimerase activity because of mutations in the epimerase domain of the Gne gene.
Hong Y; Stanley P
J Biol Chem; 2003 Dec; 278(52):53045-54. PubMed ID: 14561743
[TBL] [Abstract][Full Text] [Related]
5. A bifunctional enzyme catalyzes the first two steps in N-acetylneuraminic acid biosynthesis of rat liver. Purification and characterization of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase.
Hinderlich S; Stäsche R; Zeitler R; Reutter W
J Biol Chem; 1997 Sep; 272(39):24313-8. PubMed ID: 9305887
[TBL] [Abstract][Full Text] [Related]
6. Safety, pharmacokinetics and sialic acid production after oral administration of N-acetylmannosamine (ManNAc) to subjects with GNE myopathy.
Xu X; Wang AQ; Latham LL; Celeste F; Ciccone C; Malicdan MC; Goldspiel B; Terse P; Cradock J; Yang N; Yorke S; McKew JC; Gahl WA; Huizing M; Carrillo N
Mol Genet Metab; 2017 Sep; 122(1-2):126-134. PubMed ID: 28641925
[TBL] [Abstract][Full Text] [Related]
7. Tumour suppressor p16(INK4a) - anoikis-favouring decrease in N/O-glycan/cell surface sialylation by down-regulation of enzymes in sialic acid biosynthesis in tandem in a pancreatic carcinoma model.
Amano M; Eriksson H; Manning JC; Detjen KM; André S; Nishimura S; Lehtiö J; Gabius HJ
FEBS J; 2012 Nov; 279(21):4062-80. PubMed ID: 22943525
[TBL] [Abstract][Full Text] [Related]
8. A bifunctional enzyme catalyzes the first two steps in N-acetylneuraminic acid biosynthesis of rat liver. Molecular cloning and functional expression of UDP-N-acetyl-glucosamine 2-epimerase/N-acetylmannosamine kinase.
Stäsche R; Hinderlich S; Weise C; Effertz K; Lucka L; Moormann P; Reutter W
J Biol Chem; 1997 Sep; 272(39):24319-24. PubMed ID: 9305888
[TBL] [Abstract][Full Text] [Related]
9. Long-term ethanol consumption selectively impairs ganglioside pathway in rat brain.
Ghosh P; Ender I; Hale EA
Alcohol Clin Exp Res; 1998 Sep; 22(6):1220-6. PubMed ID: 9756036
[TBL] [Abstract][Full Text] [Related]
10. A mutation in a ganglioside biosynthetic enzyme, ST3GAL5, results in salt & pepper syndrome, a neurocutaneous disorder with altered glycolipid and glycoprotein glycosylation.
Boccuto L; Aoki K; Flanagan-Steet H; Chen CF; Fan X; Bartel F; Petukh M; Pittman A; Saul R; Chaubey A; Alexov E; Tiemeyer M; Steet R; Schwartz CE
Hum Mol Genet; 2014 Jan; 23(2):418-33. PubMed ID: 24026681
[TBL] [Abstract][Full Text] [Related]
11. Use of a cell-free system to determine UDP-N-acetylglucosamine 2-epimerase and N-acetylmannosamine kinase activities in human hereditary inclusion body myopathy.
Sparks SE; Ciccone C; Lalor M; Orvisky E; Klootwijk R; Savelkoul PJ; Dalakas MC; Krasnewich DM; Gahl WA; Huizing M
Glycobiology; 2005 Nov; 15(11):1102-10. PubMed ID: 15987957
[TBL] [Abstract][Full Text] [Related]
12. The tetrameric structure of sialic acid-synthesizing UDP-GlcNAc 2-epimerase from
Ko TP; Lai SJ; Hsieh TJ; Yang CS; Chen Y
J Biol Chem; 2018 Jun; 293(26):10119-10127. PubMed ID: 29764940
[TBL] [Abstract][Full Text] [Related]
13. The first committed step in the biosynthesis of sialic acid by Escherichia coli K1 does not involve a phosphorylated N-acetylmannosamine intermediate.
Ringenberg MA; Steenbergen SM; Vimr ER
Mol Microbiol; 2003 Nov; 50(3):961-75. PubMed ID: 14617154
[TBL] [Abstract][Full Text] [Related]
14. Monosialyl Ganglioside GM3 Decreases Apolipoprotein B-100 Secretion in Liver Cells.
Choi H; Jin UH; Kang SK; Abekura F; Park JY; Kwon KM; Suh SJ; Cho SH; Ha KT; Lee YC; Chung TW; Kim CH
J Cell Biochem; 2017 Aug; 118(8):2168-2181. PubMed ID: 28019668
[TBL] [Abstract][Full Text] [Related]
15. GlcNAc 2-epimerase can serve a catabolic role in sialic acid metabolism.
Luchansky SJ; Yarema KJ; Takahashi S; Bertozzi CR
J Biol Chem; 2003 Mar; 278(10):8035-42. PubMed ID: 12499362
[TBL] [Abstract][Full Text] [Related]
16. Engineering sialic acid synthetic ability into insect cells: identifying metabolic bottlenecks and devising strategies to overcome them.
Viswanathan K; Lawrence S; Hinderlich S; Yarema KJ; Lee YC; Betenbaugh MJ
Biochemistry; 2003 Dec; 42(51):15215-25. PubMed ID: 14690432
[TBL] [Abstract][Full Text] [Related]
17. Neural-specific alterations in glycosphingolipid biosynthesis and cell signaling associated with two human ganglioside GM3 synthase deficiency variants.
Dookwah M; Wagner SK; Ishihara M; Yu SH; Ulrichs H; Kulik MJ; Zeltner N; Dalton S; Strauss KA; Aoki K; Steet R; Tiemeyer M
Hum Mol Genet; 2023 Dec; 32(24):3323-3341. PubMed ID: 37676252
[TBL] [Abstract][Full Text] [Related]
18. GNE Myopathy and Cell Apoptosis: A Comparative Mutation Analysis.
Singh R; Arya R
Mol Neurobiol; 2016 Jul; 53(5):3088-3101. PubMed ID: 25976366
[TBL] [Abstract][Full Text] [Related]
19. A novel approach to decrease sialic acid expression in cells by a C-3-modified N-acetylmannosamine.
Wratil PR; Rigol S; Solecka B; Kohla G; Kannicht C; Reutter W; Giannis A; Nguyen LD
J Biol Chem; 2014 Nov; 289(46):32056-32063. PubMed ID: 25278018
[TBL] [Abstract][Full Text] [Related]
20. Enhanced sialylation of recombinant human erythropoietin in Chinese hamster ovary cells by combinatorial engineering of selected genes.
Son YD; Jeong YT; Park SY; Kim JH
Glycobiology; 2011 Aug; 21(8):1019-28. PubMed ID: 21436238
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]