171 related articles for article (PubMed ID: 16857362)
1. Allele-specific RNAi selectively silences mutant SOD1 and achieves significant therapeutic benefit in vivo.
Xia X; Zhou H; Huang Y; Xu Z
Neurobiol Dis; 2006 Sep; 23(3):578-86. PubMed ID: 16857362
[TBL] [Abstract][Full Text] [Related]
2. Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis.
Ding H; Schwarz DS; Keene A; Affar el B; Fenton L; Xia X; Shi Y; Zamore PD; Xu Z
Aging Cell; 2003 Aug; 2(4):209-17. PubMed ID: 12934714
[TBL] [Abstract][Full Text] [Related]
3. An RNAi strategy for treatment of amyotrophic lateral sclerosis caused by mutant Cu,Zn superoxide dismutase.
Xia XG; Zhou H; Zhou S; Yu Y; Wu R; Xu Z
J Neurochem; 2005 Jan; 92(2):362-7. PubMed ID: 15663483
[TBL] [Abstract][Full Text] [Related]
4. In vivo application of an RNAi strategy for the selective suppression of a mutant allele.
Kubodera T; Yamada H; Anzai M; Ohira S; Yokota S; Hirai Y; Mochizuki H; Shimada T; Mitani T; Mizusawa H; Yokota T
Hum Gene Ther; 2011 Jan; 22(1):27-34. PubMed ID: 20649474
[TBL] [Abstract][Full Text] [Related]
5. Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model.
Ralph GS; Radcliffe PA; Day DM; Carthy JM; Leroux MA; Lee DC; Wong LF; Bilsland LG; Greensmith L; Kingsman SM; Mitrophanous KA; Mazarakis ND; Azzouz M
Nat Med; 2005 Apr; 11(4):429-33. PubMed ID: 15768029
[TBL] [Abstract][Full Text] [Related]
6. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
Jaarsma D; Haasdijk ED; Grashorn JA; Hawkins R; van Duijn W; Verspaget HW; London J; Holstege JC
Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261
[TBL] [Abstract][Full Text] [Related]
7. [RNAi and neurological disease].
Yokota T
Rinsho Shinkeigaku; 2005 Nov; 45(11):973-5. PubMed ID: 16447777
[TBL] [Abstract][Full Text] [Related]
8. RNA interference protects against ALS in mouse model.
Burton A
Lancet Neurol; 2005 May; 4(5):274-5. PubMed ID: 15861555
[No Abstract] [Full Text] [Related]
9. Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS.
Raoul C; Abbas-Terki T; Bensadoun JC; Guillot S; Haase G; Szulc J; Henderson CE; Aebischer P
Nat Med; 2005 Apr; 11(4):423-8. PubMed ID: 15768028
[TBL] [Abstract][Full Text] [Related]
10. Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA.
Wang J; Xu G; Slunt HH; Gonzales V; Coonfield M; Fromholt D; Copeland NG; Jenkins NA; Borchelt DR
Neurobiol Dis; 2005 Dec; 20(3):943-52. PubMed ID: 16046140
[TBL] [Abstract][Full Text] [Related]
11. Silencing strategies for therapy of SOD1-mediated ALS.
van Zundert B; Brown RH
Neurosci Lett; 2017 Jan; 636():32-39. PubMed ID: 27507699
[TBL] [Abstract][Full Text] [Related]
12. Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues.
Watanabe M; Dykes-Hoberg M; Culotta VC; Price DL; Wong PC; Rothstein JD
Neurobiol Dis; 2001 Dec; 8(6):933-41. PubMed ID: 11741389
[TBL] [Abstract][Full Text] [Related]
13. RNA interference-mediated silencing of mutant superoxide dismutase rescues cyclosporin A-induced death in cultured neuroblastoma cells.
Maxwell MM; Pasinelli P; Kazantsev AG; Brown RH
Proc Natl Acad Sci U S A; 2004 Mar; 101(9):3178-83. PubMed ID: 14981234
[TBL] [Abstract][Full Text] [Related]
14. Therapeutic rAAVrh10 Mediated SOD1 Silencing in Adult SOD1(G93A) Mice and Nonhuman Primates.
Borel F; Gernoux G; Cardozo B; Metterville JP; Toro Cabrera GC; Song L; Su Q; Gao GP; Elmallah MK; Brown RH; Mueller C
Hum Gene Ther; 2016 Jan; 27(1):19-31. PubMed ID: 26710998
[TBL] [Abstract][Full Text] [Related]
15. Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice.
Clement AM; Nguyen MD; Roberts EA; Garcia ML; Boillée S; Rule M; McMahon AP; Doucette W; Siwek D; Ferrante RJ; Brown RH; Julien JP; Goldstein LS; Cleveland DW
Science; 2003 Oct; 302(5642):113-7. PubMed ID: 14526083
[TBL] [Abstract][Full Text] [Related]
16. Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS.
Turner BJ; Talbot K
Prog Neurobiol; 2008 May; 85(1):94-134. PubMed ID: 18282652
[TBL] [Abstract][Full Text] [Related]
17. Downregulation of Homer1b/c in SOD1 G93A Models of ALS: A Novel Mechanism of Neuroprotective Effect of Lithium and Valproic Acid.
Jiang HZ; Wang SY; Yin X; Jiang HQ; Wang XD; Wang J; Wang TH; Qi Y; Yang YQ; Wang Y; Zhang CT; Feng HL
Int J Mol Sci; 2016 Dec; 17(12):. PubMed ID: 27999308
[TBL] [Abstract][Full Text] [Related]
18. RNAi therapy: dominant disease gene gets silenced.
Xu Z; Xia XG
Gene Ther; 2005 Aug; 12(15):1159-60. PubMed ID: 15858609
[No Abstract] [Full Text] [Related]
19. Design of functional small interfering RNAs targeting amyotrophic lateral sclerosis-associated mutant alleles.
Geng CM; Ding HL
Chin Med J (Engl); 2011 Jan; 124(1):106-10. PubMed ID: 21362317
[TBL] [Abstract][Full Text] [Related]
20. HoxB2 binds mutant SOD1 and is altered in transgenic model of ALS.
Zhai J; Lin H; Canete-Soler R; Schlaepfer WW
Hum Mol Genet; 2005 Sep; 14(18):2629-40. PubMed ID: 16079151
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
