98 related articles for article (PubMed ID: 16857728)
1. Enzyme-mediated protein haptenation of dapsone and sulfamethoxazole in human keratinocytes: I. Expression and role of cytochromes P450.
Vyas PM; Roychowdhury S; Khan FD; Prisinzano TE; Lamba J; Schuetz EG; Blaisdell J; Goldstein JA; Munson KL; Hines RN; Svensson CK
J Pharmacol Exp Ther; 2006 Oct; 319(1):488-96. PubMed ID: 16857728
[TBL] [Abstract][Full Text] [Related]
2. Enzyme-mediated protein haptenation of dapsone and sulfamethoxazole in human keratinocytes: II. Expression and role of flavin-containing monooxygenases and peroxidases.
Vyas PM; Roychowdhury S; Koukouritaki SB; Hines RN; Krueger SK; Williams DE; Nauseef WM; Svensson CK
J Pharmacol Exp Ther; 2006 Oct; 319(1):497-505. PubMed ID: 16857727
[TBL] [Abstract][Full Text] [Related]
3. Characterization of the formation and localization of sulfamethoxazole and dapsone-associated drug-protein adducts in human epidermal keratinocytes.
Roychowdhury S; Vyas PM; Reilly TP; Gaspari AA; Svensson CK
J Pharmacol Exp Ther; 2005 Jul; 314(1):43-52. PubMed ID: 15784651
[TBL] [Abstract][Full Text] [Related]
4. Reactive oxygen species generation and its role in the differential cytotoxicity of the arylhydroxylamine metabolites of sulfamethoxazole and dapsone in normal human epidermal keratinocytes.
Vyas PM; Roychowdhury S; Woster PM; Svensson CK
Biochem Pharmacol; 2005 Jul; 70(2):275-86. PubMed ID: 15894292
[TBL] [Abstract][Full Text] [Related]
5. Bioactivation, protein haptenation, and toxicity of sulfamethoxazole and dapsone in normal human dermal fibroblasts.
Bhaiya P; Roychowdhury S; Vyas PM; Doll MA; Hein DW; Svensson CK
Toxicol Appl Pharmacol; 2006 Sep; 215(2):158-67. PubMed ID: 16603214
[TBL] [Abstract][Full Text] [Related]
6. Formation and uptake of arylhydroxylamine-haptenated proteins in human dendritic cells.
Roychowdhury S; Vyas PM; Svensson CK
Drug Metab Dispos; 2007 Apr; 35(4):676-81. PubMed ID: 17220235
[TBL] [Abstract][Full Text] [Related]
7. Role of human cyclooxygenase-2 in the bioactivation of dapsone and sulfamethoxazole.
Vyas PM; Roychowdhury S; Svensson CK
Drug Metab Dispos; 2006 Jan; 34(1):16-8. PubMed ID: 16214851
[TBL] [Abstract][Full Text] [Related]
8. Reduction of sulfamethoxazole and dapsone hydroxylamines by a microsomal enzyme system purified from pig liver and pig and human liver microsomes.
Clement B; Behrens D; Amschler J; Matschke K; Wolf S; Havemeyer A
Life Sci; 2005 May; 77(2):205-19. PubMed ID: 15862605
[TBL] [Abstract][Full Text] [Related]
9. Haptenation of sulfonamide reactive metabolites to cellular proteins.
Manchanda T; Hess D; Dale L; Ferguson SG; Rieder MJ
Mol Pharmacol; 2002 Nov; 62(5):1011-26. PubMed ID: 12391263
[TBL] [Abstract][Full Text] [Related]
10. Detection of haptenated proteins in organotypic human skin explant cultures exposed to dapsone.
Roychowdhury S; Cram AE; Aly A; Svensson CK
Drug Metab Dispos; 2007 Sep; 35(9):1463-5. PubMed ID: 17553916
[TBL] [Abstract][Full Text] [Related]
11. Effect of arylhydroxylamine metabolites of sulfamethoxazole and dapsone on stress signal expression in human keratinocytes.
Khan FD; Vyas PM; Gaspari AA; Svensson CK
J Pharmacol Exp Ther; 2007 Dec; 323(3):771-7. PubMed ID: 17766678
[TBL] [Abstract][Full Text] [Related]
12. Effect of pro-inflammatory cytokines on the toxicity of the arylhydroxylamine metabolites of sulphamethoxazole and dapsone in normal human keratinocytes.
Khan FD; Roychowdhury S; Nemes R; Vyas PM; Woster PM; Svensson CK
Toxicology; 2006 Feb; 218(2-3):90-9. PubMed ID: 16289751
[TBL] [Abstract][Full Text] [Related]
13. A role for bioactivation and covalent binding within epidermal keratinocytes in sulfonamide-induced cutaneous drug reactions.
Reilly TP; Lash LH; Doll MA; Hein DW; Woster PM; Svensson CK
J Invest Dermatol; 2000 Jun; 114(6):1164-73. PubMed ID: 10844561
[TBL] [Abstract][Full Text] [Related]
14. Sulfonamide-induced reactions in desensitized patients with AIDS--the role of covalent protein haptenation by sulfamethoxazole.
Gruchalla RS; Pesenko RD; Do TT; Skiest DJ
J Allergy Clin Immunol; 1998 Mar; 101(3):371-8. PubMed ID: 9525454
[TBL] [Abstract][Full Text] [Related]
15. CYP2C8/9 mediate dapsone N-hydroxylation at clinical concentrations of dapsone.
Winter HR; Wang Y; Unadkat JD
Drug Metab Dispos; 2000 Aug; 28(8):865-8. PubMed ID: 10901692
[TBL] [Abstract][Full Text] [Related]
16. Cellular disposition of sulphamethoxazole and its metabolites: implications for hypersensitivity.
Naisbitt DJ; Hough SJ; Gill HJ; Pirmohamed M; Kitteringham NR; Park BK
Br J Pharmacol; 1999 Mar; 126(6):1393-407. PubMed ID: 10217534
[TBL] [Abstract][Full Text] [Related]
17. Methemoglobin formation by hydroxylamine metabolites of sulfamethoxazole and dapsone: implications for differences in adverse drug reactions.
Reilly TP; Woster PM; Svensson CK
J Pharmacol Exp Ther; 1999 Mar; 288(3):951-9. PubMed ID: 10027831
[TBL] [Abstract][Full Text] [Related]
18. Multiple adduction reactions of nitroso sulfamethoxazole with cysteinyl residues of peptides and proteins: implications for hapten formation.
Callan HE; Jenkins RE; Maggs JL; Lavergne SN; Clarke SE; Naisbitt DJ; Park BK
Chem Res Toxicol; 2009 May; 22(5):937-48. PubMed ID: 19358516
[TBL] [Abstract][Full Text] [Related]
19. N4-hydroxylation of sulfamethoxazole by cytochrome P450 of the cytochrome P4502C subfamily and reduction of sulfamethoxazole hydroxylamine in human and rat hepatic microsomes.
Cribb AE; Spielberg SP; Griffin GP
Drug Metab Dispos; 1995 Mar; 23(3):406-14. PubMed ID: 7628308
[TBL] [Abstract][Full Text] [Related]
20. Changes in gene expression induced by aromatic amine drugs: testing the danger hypothesis.
Ng W; Uetrecht J
J Immunotoxicol; 2013; 10(2):178-91. PubMed ID: 22970684
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
