BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

254 related articles for article (PubMed ID: 16863439)

  • 1. Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition.
    Jedlitschky G; Hoffmann U; Kroemer HK
    Expert Opin Drug Metab Toxicol; 2006 Jun; 2(3):351-66. PubMed ID: 16863439
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Substrates and inhibitors of human multidrug resistance associated proteins and the implications in drug development.
    Zhou SF; Wang LL; Di YM; Xue CC; Duan W; Li CG; Li Y
    Curr Med Chem; 2008; 15(20):1981-2039. PubMed ID: 18691054
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance.
    König J; Nies AT; Cui Y; Leier I; Keppler D
    Biochim Biophys Acta; 1999 Dec; 1461(2):377-94. PubMed ID: 10581368
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of expression of the multidrug resistance-associated protein 2 (MRP2) and its role in drug disposition.
    Gerk PM; Vore M
    J Pharmacol Exp Ther; 2002 Aug; 302(2):407-15. PubMed ID: 12130697
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hepatic secretion of conjugated drugs and endogenous substances.
    Keppler D; König J
    Semin Liver Dis; 2000; 20(3):265-72. PubMed ID: 11076395
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Impaired protein maturation of the conjugate export pump multidrug resistance protein 2 as a consequence of a deletion mutation in Dubin-Johnson syndrome.
    Keitel V; Kartenbeck J; Nies AT; Spring H; Brom M; Keppler D
    Hepatology; 2000 Dec; 32(6):1317-28. PubMed ID: 11093739
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Exon-intron organization of the human multidrug-resistance protein 2 (MRP2) gene mutated in Dubin-Johnson syndrome.
    Tsujii H; König J; Rost D; Stöckel B; Leuschner U; Keppler D
    Gastroenterology; 1999 Sep; 117(3):653-60. PubMed ID: 10464142
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity.
    Ito K; Oleschuk CJ; Westlake C; Vasa MZ; Deeley RG; Cole SP
    J Biol Chem; 2001 Oct; 276(41):38108-14. PubMed ID: 11500505
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The apical conjugate efflux pump ABCC2 (MRP2).
    Nies AT; Keppler D
    Pflugers Arch; 2007 Feb; 453(5):643-59. PubMed ID: 16847695
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dual hereditary jaundice: simultaneous occurrence of mutations causing Gilbert's and Dubin-Johnson syndrome.
    Cebecauerova D; Jirasek T; Budisova L; Mandys V; Volf V; Novotna Z; Subhanova I; Hrebicek M; Elleder M; Jirsa M
    Gastroenterology; 2005 Jul; 129(1):315-20. PubMed ID: 16012956
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A common Dubin-Johnson syndrome mutation impairs protein maturation and transport activity of MRP2 (ABCC2).
    Keitel V; Nies AT; Brom M; Hummel-Eisenbeiss J; Spring H; Keppler D
    Am J Physiol Gastrointest Liver Physiol; 2003 Jan; 284(1):G165-74. PubMed ID: 12388192
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A mutation in the drug transporter gene ABCC2 associated with impaired methotrexate elimination.
    Hulot JS; Villard E; Maguy A; Morel V; Mir L; Tostivint I; William-Faltaos D; Fernandez C; Hatem S; Deray G; Komajda M; Leblond V; Lechat P
    Pharmacogenet Genomics; 2005 May; 15(5):277-85. PubMed ID: 15864128
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel mutations in the Dubin-Johnson syndrome gene ABCC2/MRP2 and associated biochemical changes.
    Devgun MS; El-Nujumi AM; O'Dowd GJ; Barbu V; Poupon R
    Ann Clin Biochem; 2012 Nov; 49(Pt 6):609-12. PubMed ID: 23065530
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The roles of MRP2, MRP3, OATP1B1, and OATP1B3 in conjugated hyperbilirubinemia.
    Keppler D
    Drug Metab Dispos; 2014 Apr; 42(4):561-5. PubMed ID: 24459177
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A new mutation of the ATP-binding cassette, sub-family C, member 2 (ABCC2) gene in a Japanese patient with Dubin-Johnson syndrome.
    Tate G; Li M; Suzuki T; Mitsuya T
    Genes Genet Syst; 2002 Apr; 77(2):117-21. PubMed ID: 12087194
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Carcinogen and anticancer drug transport by Mrp2 in vivo: studies using Mrp2 (Abcc2) knockout mice.
    Vlaming ML; Mohrmann K; Wagenaar E; de Waart DR; Elferink RP; Lagas JS; van Tellingen O; Vainchtein LD; Rosing H; Beijnen JH; Schellens JH; Schinkel AH
    J Pharmacol Exp Ther; 2006 Jul; 318(1):319-27. PubMed ID: 16611851
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ABCC2/Abcc2: a multispecific transporter with dominant excretory functions.
    Jemnitz K; Heredi-Szabo K; Janossy J; Ioja E; Vereczkey L; Krajcsi P
    Drug Metab Rev; 2010 Aug; 42(3):402-36. PubMed ID: 20082599
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Neonatal Dubin-Johnson syndrome: long-term follow-up and MRP2 mutations study.
    Lee JH; Chen HL; Chen HL; Ni YH; Hsu HY; Chang MH
    Pediatr Res; 2006 Apr; 59(4 Pt 1):584-9. PubMed ID: 16549534
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of a novel 974C-->G nonsense mutation of the MRP2/ABCC2 gene in a patient with Dubin-Johnson syndrome and analysis of the effects of rifampicin and ursodeoxycholic acid on serum bilirubin and bile acids.
    Corpechot C; Ping C; Wendum D; Matsuda F; Barbu V; Poupon R
    Am J Gastroenterol; 2006 Oct; 101(10):2427-32. PubMed ID: 16952291
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): its impact on drug disposition.
    Suzuki H; Sugiyama Y
    Adv Drug Deliv Rev; 2002 Nov; 54(10):1311-31. PubMed ID: 12406647
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.