These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

196 related articles for article (PubMed ID: 16863475)

  • 1. A flexible approach for optimising in silico ADME/Tox characterisation of lead candidates.
    Bidault Y
    Expert Opin Drug Metab Toxicol; 2006 Feb; 2(1):157-68. PubMed ID: 16863475
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A model validation and consensus building environment.
    Abshear T; Banik GM; D'Souza ML; Nedwed K; Peng C
    SAR QSAR Environ Res; 2006 Jun; 17(3):311-21. PubMed ID: 16815770
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In silico ADME-Tox modeling: progress and prospects.
    Alqahtani S
    Expert Opin Drug Metab Toxicol; 2017 Nov; 13(11):1147-1158. PubMed ID: 28988506
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ADME-Tox in drug discovery: integration of experimental and computational technologies.
    Yu H; Adedoyin A
    Drug Discov Today; 2003 Sep; 8(18):852-61. PubMed ID: 12963322
    [TBL] [Abstract][Full Text] [Related]  

  • 5.
    Ekins S; Lane TR; Urbina F; Puhl AC
    Xenobiotica; 2024 Jul; 54(7):352-358. PubMed ID: 37539466
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Applying machine learning techniques for ADME-Tox prediction: a review.
    Maltarollo VG; Gertrudes JC; Oliveira PR; Honorio KM
    Expert Opin Drug Metab Toxicol; 2015 Feb; 11(2):259-71. PubMed ID: 25440524
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Natural modulators of nonalcoholic fatty liver disease: Mode of action analysis and in silico ADME-Tox prediction.
    Al Sharif M; Alov P; Vitcheva V; Diukendjieva A; Mori M; Botta B; Tsakovska I; Pajeva I
    Toxicol Appl Pharmacol; 2017 Dec; 337():45-66. PubMed ID: 29056366
    [TBL] [Abstract][Full Text] [Related]  

  • 8. From in vivo to in vitro/in silico ADME: progress and challenges.
    Van de Waterbeemd H
    Expert Opin Drug Metab Toxicol; 2005 Jun; 1(1):1-4. PubMed ID: 16922647
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A hierarchical screening methodology for physicochemical/ADME/Tox profiling.
    DeWitte RS; Robins RH
    Expert Opin Drug Metab Toxicol; 2006 Oct; 2(5):805-17. PubMed ID: 17014396
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of ADME characteristics in drug discovery and their in silico evaluation: in silico screening of chemicals for their metabolic stability.
    Gombar VK; Silver IS; Zhao Z
    Curr Top Med Chem; 2003; 3(11):1205-25. PubMed ID: 12769701
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Troubleshooting computational methods in drug discovery.
    Kortagere S; Ekins S
    J Pharmacol Toxicol Methods; 2010; 61(2):67-75. PubMed ID: 20176118
    [TBL] [Abstract][Full Text] [Related]  

  • 12. From physicochemistry to absorption and distribution: predictive mechanistic modelling and computational tools.
    Willmann S; Lippert J; Schmitt W
    Expert Opin Drug Metab Toxicol; 2005 Jun; 1(1):159-68. PubMed ID: 16922658
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vitro preclinical lead optimisation technologies (PLOTs) in pharmaceutical development.
    Atterwill CK; Wing MG
    Toxicol Lett; 2002 Feb; 127(1-3):143-51. PubMed ID: 12052652
    [TBL] [Abstract][Full Text] [Related]  

  • 14. In silico ADME/Tox: the state of the art.
    Ekins S; Rose J
    J Mol Graph Model; 2002 Jan; 20(4):305-9. PubMed ID: 11858639
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Preclinical pharmacokinetics: an approach towards safer and efficacious drugs.
    Singh SS
    Curr Drug Metab; 2006 Feb; 7(2):165-82. PubMed ID: 16472106
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Computational prediction of human drug metabolism.
    Ekins S; Andreyev S; Ryabov A; Kirillov E; Rakhmatulin EA; Bugrim A; Nikolskaya T
    Expert Opin Drug Metab Toxicol; 2005 Aug; 1(2):303-24. PubMed ID: 16922645
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In silico toxicology for the pharmaceutical sciences.
    Valerio LG
    Toxicol Appl Pharmacol; 2009 Dec; 241(3):356-70. PubMed ID: 19716836
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Systems-ADME/Tox: resources and network approaches.
    Ekins S
    J Pharmacol Toxicol Methods; 2006; 53(1):38-66. PubMed ID: 16054403
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Recent advances in computational prediction of drug absorption and permeability in drug discovery.
    Hou T; Wang J; Zhang W; Wang W; Xu X
    Curr Med Chem; 2006; 13(22):2653-67. PubMed ID: 17017917
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox).
    Szakács G; Váradi A; Ozvegy-Laczka C; Sarkadi B
    Drug Discov Today; 2008 May; 13(9-10):379-93. PubMed ID: 18468555
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.