BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

120 related articles for article (PubMed ID: 16870249)

  • 1. Activating Notch1 mutations are an early event in T-cell malignancy of Ikaros point mutant Plastic/+ mice.
    Mantha S; Ward M; McCafferty J; Herron A; Palomero T; Ferrando A; Bank A; Richardson C
    Leuk Res; 2007 Mar; 31(3):321-7. PubMed ID: 16870249
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ikaros is a critical target during simultaneous exposure to X-rays and N-ethyl-N-nitrosourea in mouse T-cell lymphomagenesis.
    Hirano S; Kakinuma S; Amasaki Y; Nishimura M; Imaoka T; Fujimoto S; Hino O; Shimada Y
    Int J Cancer; 2013 Jan; 132(2):259-68. PubMed ID: 22684892
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cooperation of Gata3, c-Myc and Notch in malignant transformation of double positive thymocytes.
    van Hamburg JP; de Bruijn MJ; Dingjan GM; Beverloo HB; Diepstraten H; Ling KW; Hendriks RW
    Mol Immunol; 2008 Jun; 45(11):3085-95. PubMed ID: 18471881
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ikaros represses the transcriptional response to Notch signaling in T-cell development.
    Kleinmann E; Geimer Le Lay AS; Sellars M; Kastner P; Chan S
    Mol Cell Biol; 2008 Dec; 28(24):7465-75. PubMed ID: 18852286
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Notch activation is an early and critical event during T-Cell leukemogenesis in Ikaros-deficient mice.
    Dumortier A; Jeannet R; Kirstetter P; Kleinmann E; Sellars M; dos Santos NR; Thibault C; Barths J; Ghysdael J; Punt JA; Kastner P; Chan S
    Mol Cell Biol; 2006 Jan; 26(1):209-20. PubMed ID: 16354692
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Helios deficiency has minimal impact on T cell development and function.
    Cai Q; Dierich A; Oulad-Abdelghani M; Chan S; Kastner P
    J Immunol; 2009 Aug; 183(4):2303-11. PubMed ID: 19620299
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Point mutations and deletions in the znfn1a1/ikaros gene in chemically induced murine lymphomas.
    Karlsson A; Söderkvist P; Zhuang SM
    Cancer Res; 2002 May; 62(9):2650-3. PubMed ID: 11980663
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Frequent retention of heterozygosity for point mutations in p53 and Ikaros in N-ethyl-N-nitrosourea-induced mouse thymic lymphomas.
    Kakinuma S; Nishimura M; Kubo A; Nagai JY; Amasaki Y; Majima HJ; Sado T; Shimada Y
    Mutat Res; 2005 May; 572(1-2):132-41. PubMed ID: 15790496
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Defective expression of Notch1 and Notch2 in connection to alterations of c-Myc and Ikaros in gamma-radiation-induced mouse thymic lymphomas.
    López-Nieva P; Santos J; Fernández-Piqueras J
    Carcinogenesis; 2004 Jul; 25(7):1299-304. PubMed ID: 14976135
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Combined exposure to X-irradiation followed by N-ethyl-N-nitrosourea treatment alters the frequency and spectrum of Ikaros point mutations in murine T-cell lymphoma.
    Kakinuma S; Nishimura M; Amasaki Y; Takada M; Yamauchi K; Sudo S; Shang Y; Doi K; Yoshinaga S; Shimada Y
    Mutat Res; 2012 Sep; 737(1-2):43-50. PubMed ID: 22706209
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stage specific over-expression of the dominant negative Ikaros 6 reveals distinct role of Ikaros throughout human B-cell differentiation.
    Tonnelle C; Dijon M; Moreau T; Garulli C; Bardin F; Chabannon C
    Mol Immunol; 2009 May; 46(8-9):1736-43. PubMed ID: 19285729
    [TBL] [Abstract][Full Text] [Related]  

  • 12. NOTCH1 mutations in T-cell acute lymphoblastic leukemia: prognostic significance and implication in multifactorial leukemogenesis.
    Zhu YM; Zhao WL; Fu JF; Shi JY; Pan Q; Hu J; Gao XD; Chen B; Li JM; Xiong SM; Gu LJ; Tang JY; Liang H; Jiang H; Xue YQ; Shen ZX; Chen Z; Chen SJ
    Clin Cancer Res; 2006 May; 12(10):3043-9. PubMed ID: 16707600
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A full-length Notch1 allele is dispensable for transformation associated with a provirally activated truncated Notch1 allele in Moloney MuLV-infected MMTV(D)/myc transgenic mice.
    Girard L; Jolicoeur P
    Oncogene; 1998 Jan; 16(4):517-22. PubMed ID: 9484841
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Homozygous deletions and point mutations of the Ikaros gene in gamma-ray-induced mouse thymic lymphomas.
    Okano H; Saito Y; Miyazawa T; Shinbo T; Chou D; Kosugi S; Takahashi Y; Odani S; Niwa O; Kominami R
    Oncogene; 1999 Nov; 18(48):6677-83. PubMed ID: 10597273
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cooperation between somatic Ikaros and Notch1 mutations at the inception of T-ALL.
    Sontani Y; Chapman G; Papathanasiou P; Dunwoodie S; Goodnow CC; Hoyne GF
    Leuk Res; 2011 Nov; 35(11):1512-9. PubMed ID: 21840596
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia.
    Vilimas T; Mascarenhas J; Palomero T; Mandal M; Buonamici S; Meng F; Thompson B; Spaulding C; Macaroun S; Alegre ML; Kee BL; Ferrando A; Miele L; Aifantis I
    Nat Med; 2007 Jan; 13(1):70-7. PubMed ID: 17173050
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies.
    Fiorini E; Merck E; Wilson A; Ferrero I; Jiang W; Koch U; Auderset F; Laurenti E; Tacchini-Cottier F; Pierres M; Radtke F; Luther SA; Macdonald HR
    J Immunol; 2009 Dec; 183(11):7212-22. PubMed ID: 19915064
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ikaros has a crucial role in regulation of B cell receptor signaling.
    Nera KP; Alinikula J; Terho P; Narvi E; Törnquist K; Kurosaki T; Buerstedde JM; Lassila O
    Eur J Immunol; 2006 Mar; 36(3):516-25. PubMed ID: 16482514
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Notch1 mutations are important for leukemic transformation in murine models of precursor-T leukemia/lymphoma.
    Lin YW; Nichols RA; Letterio JJ; Aplan PD
    Blood; 2006 Mar; 107(6):2540-3. PubMed ID: 16282337
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Notch in T-ALL: new players in a complex disease.
    Koch U; Radtke F
    Trends Immunol; 2011 Sep; 32(9):434-42. PubMed ID: 21775206
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.