281 related articles for article (PubMed ID: 16870441)
1. Synthesis and evaluation of thiazepines as interleukin-1beta converting enzyme (ICE) inhibitors.
Ellis CD; Oppong KA; Laufersweiler MC; O'Neil SV; Soper DL; Wang Y; Wos JA; Fancher AN; Lu W; Suchanek MK; Wang RL; De B; Demuth TP
Bioorg Med Chem Lett; 2006 Sep; 16(18):4728-32. PubMed ID: 16870441
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and evaluation of tricyclic pyrrolopyrimidinones as dipeptide mimetics: inhibition of interleukin-1beta-converting enzyme.
Laufersweiler MC; Wang Y; Soper DL; Suchanek MK; Fancher AN; Lu W; Wang RL; Oppong KA; Ellis CD; Baize MW; O'Neil SV; Wos JA; Demuth TP
Bioorg Med Chem Lett; 2005 Oct; 15(19):4322-6. PubMed ID: 16046129
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and evaluation of unsaturated caprolactams as interleukin-1beta converting enzyme (ICE) inhibitors.
Wang Y; O'Neil SV; Wos JA; Oppong KA; Laufersweiler MC; Soper DL; Ellis CD; Baize MW; Fancher AN; Lu W; Suchanek MK; Wang RL; Schwecke WP; Cruze CA; Buchalova M; Belkin M; De B; Demuth TP
Bioorg Med Chem; 2007 Feb; 15(3):1311-22. PubMed ID: 17127070
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and evaluation of novel 1-(2-acylhydrazinocarbonyl)-cycloalkyl carboxamides as interleukin-1beta converting enzyme (ICE) inhibitors.
Soper DL; Sheville J; O'Neil SV; Wang Y; Laufersweiler MC; Oppong KA; Wos JA; Ellis CD; Fancher AN; Lu W; Suchanek MK; Wang RL; De B; Demuth TP
Bioorg Med Chem Lett; 2006 Aug; 16(16):4233-6. PubMed ID: 16782334
[TBL] [Abstract][Full Text] [Related]
5. Enantio- and diastereoselective total synthesis of EI-1941-1, -2, and -3, inhibitors of interleukin-1beta converting enzyme, and biological properties of their derivatives.
Shoji M; Uno T; Kakeya H; Onose R; Shiina I; Osada H; Hayashi Y
J Org Chem; 2005 Nov; 70(24):9905-15. PubMed ID: 16292821
[TBL] [Abstract][Full Text] [Related]
6. Synthesis of 2-substituted-N-carboxymethyl-1,5-benzothiazepin-4-ones and -1,4-benzothiazin-3-ones and their evaluation as angiotensin converting enzyme inhibitors.
Trapani G; Latrofa A; Franco M; Liso G
Farmaco; 1995 Feb; 50(2):107-12. PubMed ID: 7766274
[TBL] [Abstract][Full Text] [Related]
7. Structure-activity relationship of 6-methylidene penems bearing tricyclic heterocycles as broad-spectrum beta-lactamase inhibitors: crystallographic structures show unexpected binding of 1,4-thiazepine intermediates.
Venkatesan AM; Gu Y; Dos Santos O; Abe T; Agarwal A; Yang Y; Petersen PJ; Weiss WJ; Mansour TS; Nukaga M; Hujer AM; Bonomo RA; Knox JR
J Med Chem; 2004 Dec; 47(26):6556-68. PubMed ID: 15588091
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis, and biological evaluation of potent thiazine- and thiazepine-based matrix metalloproteinase inhibitors.
Almstead NG; Bradley RS; Pikul S; De B; Natchus MG; Taiwo YO; Gu F; Williams LE; Hynd BA; Janusz MJ; Dunaway CM; Mieling GE
J Med Chem; 1999 Nov; 42(22):4547-62. PubMed ID: 10579818
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and biological evaluation of acyclic triaryl (Z)-olefins possessing a 3,5-di-tert-butyl-4-hydroxyphenyl pharmacophore: dual inhibitors of cyclooxygenases and lipoxygenases.
Moreau A; Rao PN; Knaus EE
Bioorg Med Chem; 2006 Aug; 14(15):5340-50. PubMed ID: 16677817
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis, and evaluation of benzothiadiazepine hydroxamates as selective tumor necrosis factor-alpha converting enzyme inhibitors.
Cherney RJ; Duan JJ; Voss ME; Chen L; Wang L; Meyer DT; Wasserman ZR; Hardman KD; Liu RQ; Covington MB; Qian M; Mandlekar S; Christ DD; Trzaskos JM; Newton RC; Magolda RL; Wexler RR; Decicco CP
J Med Chem; 2003 May; 46(10):1811-23. PubMed ID: 12723945
[TBL] [Abstract][Full Text] [Related]
11. Pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors. Synthesis and SAR of 2-substituted 4-methyl-8-(morpholine-4-sulfonyl)-pyrrolo[3,4-c]quinoline-1,3-diones.
Kravchenko DV; Kysil VM; Tkachenko SE; Maliarchouk S; Okun IM; Ivachtchenko AV
Eur J Med Chem; 2005 Dec; 40(12):1377-83. PubMed ID: 16169127
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and biological evaluation of a novel series of 1,5-benzothiazepine derivatives as potential antimicrobial agents.
Wang L; Zhang P; Zhang X; Zhang Y; Li Y; Wang Y
Eur J Med Chem; 2009 Jul; 44(7):2815-21. PubMed ID: 19144450
[TBL] [Abstract][Full Text] [Related]
13. Synthesis, crystal structure and biological activity of beta-carboline based selective CDK4-cyclin D1 inhibitors.
García MD; Wilson AJ; Emmerson DP; Jenkins PR; Mahale S; Chaudhuri B
Org Biomol Chem; 2006 Dec; 4(24):4478-84. PubMed ID: 17268643
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and evaluation of novel 8,5-fused bicyclic peptidomimetic compounds as interleukin-1beta converting enzyme (ICE) inhibitors.
Soper DL; Sheville JX; O'Neil SV; Wang Y; Laufersweiler MC; Oppong KA; Wos JA; Ellis CD; Baize MW; Chen JJ; Fancher AN; Lu W; Suchanek MK; Wang RL; Schwecke WP; Cruze CA; Buchalova M; Belkin M; Wireko F; Ritter A; De B; Wang D; Demuth TP
Bioorg Med Chem; 2006 Dec; 14(23):7880-92. PubMed ID: 16908171
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and biological evaluation of N-acylhydrazones as inhibitors of MurC and MurD ligases.
Sink R; Kovac A; Tomasić T; Rupnik V; Boniface A; Bostock J; Chopra I; Blanot D; Masic LP; Gobec S; Zega A
ChemMedChem; 2008 Sep; 3(9):1362-70. PubMed ID: 18651694
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and biological evaluation of rhodanine derivatives as PRL-3 inhibitors.
Ahn JH; Kim SJ; Park WS; Cho SY; Ha JD; Kim SS; Kang SK; Jeong DG; Jung SK; Lee SH; Kim HM; Park SK; Lee KH; Lee CW; Ryu SE; Choi JK
Bioorg Med Chem Lett; 2006 Jun; 16(11):2996-9. PubMed ID: 16530413
[TBL] [Abstract][Full Text] [Related]
17. 1,3-Dioxo-4-methyl-2,3-dihydro-1H-pyrrolo[3,4-c]quinolines as potent caspase-3 inhibitors.
Kravchenko DV; Kysil VV; Ilyn AP; Tkachenko SE; Maliarchouk S; Okun IM; Ivachtchenko AV
Bioorg Med Chem Lett; 2005 Apr; 15(7):1841-5. PubMed ID: 15780618
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and structure-activity relationship of 4-substituted 2-(2-acetyloxyethyl)-8-(morpholine-4-sulfonyl)pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors.
Kravchenko DV; Kuzovkova YA; Kysil VM; Tkachenko SE; Maliarchouk S; Okun IM; Balakin KV; Ivachtchenko AV
J Med Chem; 2005 Jun; 48(11):3680-3. PubMed ID: 15916416
[TBL] [Abstract][Full Text] [Related]
19. Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (1).
Asano Y; Kitamura S; Ohra T; Aso K; Igata H; Tamura T; Kawamoto T; Tanaka T; Sogabe S; Matsumoto S; Yamaguchi M; Kimura H; Itoh F
Bioorg Med Chem; 2008 Apr; 16(8):4715-32. PubMed ID: 18313304
[TBL] [Abstract][Full Text] [Related]
20. Stereoselective synthesis of bioactive isosteviol derivatives as alpha-glucosidase inhibitors.
Wu Y; Yang JH; Dai GF; Liu CJ; Tian GQ; Ma WY; Tao JC
Bioorg Med Chem; 2009 Feb; 17(4):1464-73. PubMed ID: 19167896
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
