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2. ATP and MO25alpha regulate the conformational state of the STRADalpha pseudokinase and activation of the LKB1 tumour suppressor. Zeqiraj E; Filippi BM; Goldie S; Navratilova I; Boudeau J; Deak M; Alessi DR; van Aalten DM PLoS Biol; 2009 Jun; 7(6):e1000126. PubMed ID: 19513107 [TBL] [Abstract][Full Text] [Related]
3. Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD. Baas AF; Boudeau J; Sapkota GP; Smit L; Medema R; Morrice NA; Alessi DR; Clevers HC EMBO J; 2003 Jun; 22(12):3062-72. PubMed ID: 12805220 [TBL] [Abstract][Full Text] [Related]
5. Detection of the single hotspot mutation in the JH2 pseudokinase domain of Janus kinase 2 in bone marrow trephine biopsies derived from chronic myeloproliferative disorders. Bock O; Büsche G; Koop C; Schröter S; Buhr T; Kreipe H J Mol Diagn; 2006 May; 8(2):170-7. PubMed ID: 16645202 [TBL] [Abstract][Full Text] [Related]
6. Myeloproliferative disorders carrying the t(8;9) (PCM1-JAK2) translocation. Bousquet M; Brousset P Hum Pathol; 2006 Apr; 37(4):500; author reply 500-2. PubMed ID: 16564930 [No Abstract] [Full Text] [Related]
7. Allosteric protein kinase regulation by pseudokinases: insights from STRAD. Rajakulendran T; Sicheri F Sci Signal; 2010 Mar; 3(111):pe8. PubMed ID: 20197543 [TBL] [Abstract][Full Text] [Related]
8. Diagnostic assays for the JAK2 V617F mutation in chronic myeloproliferative disorders. Greiner TC Am J Clin Pathol; 2006 May; 125(5):651-3. PubMed ID: 16707363 [No Abstract] [Full Text] [Related]
9. [A recurrent mutation of the JAK2 gene in chronic myeloproliferative disorders]. Berger R Pathol Biol (Paris); 2006 May; 54(4):182-4. PubMed ID: 16084028 [No Abstract] [Full Text] [Related]
10. The V617F JAK2 mutation is uncommon in cancers and in myeloid malignancies other than the classic myeloproliferative disorders. Scott LM; Campbell PJ; Baxter EJ; Todd T; Stephens P; Edkins S; Wooster R; Stratton MR; Futreal PA; Green AR Blood; 2005 Oct; 106(8):2920-1. PubMed ID: 16204151 [No Abstract] [Full Text] [Related]
11. A unifying mutation in chronic myeloproliferative disorders. Goldman JM N Engl J Med; 2005 Apr; 352(17):1744-6. PubMed ID: 15858182 [No Abstract] [Full Text] [Related]
12. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Baxter EJ; Scott LM; Campbell PJ; East C; Fourouclas N; Swanton S; Vassiliou GS; Bench AJ; Boyd EM; Curtin N; Scott MA; Erber WN; Green AR; Lancet; 2005 Mar 19-25; 365(9464):1054-61. PubMed ID: 15781101 [TBL] [Abstract][Full Text] [Related]
13. Analysis of the LKB1-STRAD-MO25 complex. Boudeau J; Scott JW; Resta N; Deak M; Kieloch A; Komander D; Hardie DG; Prescott AR; van Aalten DM; Alessi DR J Cell Sci; 2004 Dec; 117(Pt 26):6365-75. PubMed ID: 15561763 [TBL] [Abstract][Full Text] [Related]
14. JAK2 V617F mutation in classic chronic myeloproliferative diseases: a report on a series of 349 patients. Vizmanos JL; Ormazábal C; Larráyoz MJ; Cross NC; Calasanz MJ Leukemia; 2006 Mar; 20(3):534-5. PubMed ID: 16408096 [No Abstract] [Full Text] [Related]
15. A JAK2 mutation in myeloproliferative disorders: pathogenesis and therapeutic and scientific prospects. James C; Ugo V; Casadevall N; Constantinescu SN; Vainchenker W Trends Mol Med; 2005 Dec; 11(12):546-54. PubMed ID: 16271512 [TBL] [Abstract][Full Text] [Related]
16. New insights into the pathogenesis of JAK2 V617F-positive myeloproliferative disorders and consequences for the management of patients. Villeval JL; James C; Pisani DF; Casadevall N; Vainchenker W Semin Thromb Hemost; 2006 Jun; 32(4 Pt 2):341-51. PubMed ID: 16810610 [TBL] [Abstract][Full Text] [Related]
17. JAK2 V617F: a single mutation in the myeloproliferative group of disorders. McLornan D; Percy M; McMullin MF Ulster Med J; 2006 May; 75(2):112-9. PubMed ID: 16755940 [No Abstract] [Full Text] [Related]
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19. JAK2T875N is a novel activating mutation that results in myeloproliferative disease with features of megakaryoblastic leukemia in a murine bone marrow transplantation model. Mercher T; Wernig G; Moore SA; Levine RL; Gu TL; Fröhling S; Cullen D; Polakiewicz RD; Bernard OA; Boggon TJ; Lee BH; Gilliland DG Blood; 2006 Oct; 108(8):2770-9. PubMed ID: 16804112 [TBL] [Abstract][Full Text] [Related]
20. Refractory anemia with ringed sideroblasts associated with marked thrombocytosis harbors JAK2 mutation and shows overlapping myeloproliferative and myelodysplastic features. Wang SA; Hasserjian RP; Loew JM; Sechman EV; Jones D; Hao S; Liu Q; Zhao W; Mehdi M; Galili N; Woda B; Raza A Leukemia; 2006 Sep; 20(9):1641-4. PubMed ID: 16871284 [No Abstract] [Full Text] [Related] [Next] [New Search]