263 related articles for article (PubMed ID: 16885368)
1. The Aurora kinase inhibitor VX-680 induces endoreduplication and apoptosis preferentially in cells with compromised p53-dependent postmitotic checkpoint function.
Gizatullin F; Yao Y; Kung V; Harding MW; Loda M; Shapiro GI
Cancer Res; 2006 Aug; 66(15):7668-77. PubMed ID: 16885368
[TBL] [Abstract][Full Text] [Related]
2. Combination of nutlin-3 and VX-680 selectively targets p53 mutant cells with reversible effects on cells expressing wild-type p53.
Cheok CF; Kua N; Kaldis P; Lane DP
Cell Death Differ; 2010 Sep; 17(9):1486-500. PubMed ID: 20203688
[TBL] [Abstract][Full Text] [Related]
3. p21(Waf1/Cip1) inhibition of cyclin E/Cdk2 activity prevents endoreduplication after mitotic spindle disruption.
Stewart ZA; Leach SD; Pietenpol JA
Mol Cell Biol; 1999 Jan; 19(1):205-15. PubMed ID: 9858545
[TBL] [Abstract][Full Text] [Related]
4. Concomitant inhibition of Mdm2-p53 interaction and Aurora kinases activates the p53-dependent postmitotic checkpoints and synergistically induces p53-mediated mitochondrial apoptosis along with reduced endoreduplication in acute myelogenous leukemia.
Kojima K; Konopleva M; Tsao T; Nakakuma H; Andreeff M
Blood; 2008 Oct; 112(7):2886-95. PubMed ID: 18633130
[TBL] [Abstract][Full Text] [Related]
5. Induction of p21(Waf1/Cip1) by garcinol via downregulation of p38-MAPK signaling in p53-independent H1299 lung cancer.
Yu SY; Liao CH; Chien MH; Tsai TY; Lin JK; Weng MS
J Agric Food Chem; 2014 Mar; 62(9):2085-95. PubMed ID: 24533688
[TBL] [Abstract][Full Text] [Related]
6. Clostridium difficile toxin A-induced colonocyte apoptosis involves p53-dependent p21(WAF1/CIP1) induction via p38 mitogen-activated protein kinase.
Kim H; Kokkotou E; Na X; Rhee SH; Moyer MP; Pothoulakis C; Lamont JT
Gastroenterology; 2005 Dec; 129(6):1875-88. PubMed ID: 16344056
[TBL] [Abstract][Full Text] [Related]
7. Reexpression of hSNF5 in malignant rhabdoid tumor cell lines causes cell cycle arrest through a p21(CIP1/WAF1)-dependent mechanism.
Kuwahara Y; Charboneau A; Knudsen ES; Weissman BE
Cancer Res; 2010 Mar; 70(5):1854-65. PubMed ID: 20179200
[TBL] [Abstract][Full Text] [Related]
8. Serine/threonine protein phosphatase type 5 acts upstream of p53 to regulate the induction of p21(WAF1/Cip1) and mediate growth arrest.
Zuo Z; Dean NM; Honkanen RE
J Biol Chem; 1998 May; 273(20):12250-8. PubMed ID: 9575175
[TBL] [Abstract][Full Text] [Related]
9. The p53-p21WAF1 checkpoint pathway plays a protective role in preventing DNA rereplication induced by abrogation of FOXF1 function.
Lo PK; Lee JS; Sukumar S
Cell Signal; 2012 Jan; 24(1):316-24. PubMed ID: 21964066
[TBL] [Abstract][Full Text] [Related]
10. The permissive effect of p21(Waf1/Cip1) on DNA synthesis is dependent on cell type: effect is absent in p53-inactive cells.
Weiss RH; Randour CJ
Cell Signal; 2000 Jun; 12(6):413-8. PubMed ID: 10889470
[TBL] [Abstract][Full Text] [Related]
11. TGF-beta-mediated cell cycle arrest of HPV16-immortalized human ectocervical cells correlates with decreased E6/E7 mRNA and increased p53 and p21(WAF-1) expression.
Rorke EA; Zhang D; Choo CK; Eckert RL; Jacobberger JW
Exp Cell Res; 2000 Aug; 259(1):149-57. PubMed ID: 10942587
[TBL] [Abstract][Full Text] [Related]
12. Determinants for the efficiency of anticancer drugs targeting either Aurora-A or Aurora-B kinases in human colon carcinoma cells.
Kaestner P; Stolz A; Bastians H
Mol Cancer Ther; 2009 Jul; 8(7):2046-56. PubMed ID: 19584233
[TBL] [Abstract][Full Text] [Related]
13. LYG-202 inhibits the proliferation of human colorectal carcinoma HCT-116 cells through induction of G1/S cell cycle arrest and apoptosis via p53 and p21(WAF1/Cip1) expression.
Liu W; Dai Q; Lu N; Wei L; Ha J; Rong J; Mu R; You Q; Li Z; Guo Q
Biochem Cell Biol; 2011 Jun; 89(3):287-98. PubMed ID: 21491996
[TBL] [Abstract][Full Text] [Related]
14. p53-independent inhibition of proliferation and p21(WAF1/Cip1)-modulated induction of cell death by the antioxidants N-acetylcysteine and vitamin E.
Nargi JL; Ratan RR; Griffin DE
Neoplasia; 1999 Dec; 1(6):544-56. PubMed ID: 10935502
[TBL] [Abstract][Full Text] [Related]
15. Phenoxodiol, a novel isoflavone, induces G1 arrest by specific loss in cyclin-dependent kinase 2 activity by p53-independent induction of p21WAF1/CIP1.
Aguero MF; Facchinetti MM; Sheleg Z; Senderowicz AM
Cancer Res; 2005 Apr; 65(8):3364-73. PubMed ID: 15833870
[TBL] [Abstract][Full Text] [Related]
16. Dose-response transition from cell cycle arrest to apoptosis with selective degradation of Mdm2 and p21WAF1/CIP1 in response to the novel anticancer agent, aminoflavone (NSC 686,288).
Meng LH; Kohn KW; Pommier Y
Oncogene; 2007 Jul; 26(33):4806-16. PubMed ID: 17297446
[TBL] [Abstract][Full Text] [Related]
17. The p53-p21(Cip1/WAF1) pathway is necessary for cellular senescence induced by the inhibition of protein kinase CKII in human colon cancer cells.
Kang JY; Kim JJ; Jang SY; Bae YS
Mol Cells; 2009 Nov; 28(5):489-94. PubMed ID: 19855935
[TBL] [Abstract][Full Text] [Related]
18. Sensitivity to the non-COX inhibiting celecoxib derivative, OSU03012, is p21(WAF1/CIP1) dependent.
Ding H; Han C; Guo D; Wang D; Duan W; Chen CS; D'Ambrosio SM
Int J Cancer; 2008 Dec; 123(12):2931-8. PubMed ID: 18798266
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase pathway induces p53-independent transcriptional regulation of p21(WAF1/CIP1) in human prostate carcinoma cells.
Lee SJ; Ha MJ; Lee J; Nguyen P; Choi YH; Pirnia F; Kang WK; Wang XF; Kim SJ; Trepel JB
J Biol Chem; 1998 Apr; 273(17):10618-23. PubMed ID: 9553123
[TBL] [Abstract][Full Text] [Related]
20. G1 phase accumulation induced by UCN-01 is associated with dephosphorylation of Rb and CDK2 proteins as well as induction of CDK inhibitor p21/Cip1/WAF1/Sdi1 in p53-mutated human epidermoid carcinoma A431 cells.
Akiyama T; Yoshida T; Tsujita T; Shimizu M; Mizukami T; Okabe M; Akinaga S
Cancer Res; 1997 Apr; 57(8):1495-501. PubMed ID: 9108451
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
