BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 16888811)

  • 1. Extreme sensitivity to Yondelis (Trabectedin, ET-743) in low passaged sarcoma cell lines correlates with mutated p53.
    Moneo V; Serelde BG; Fominaya J; Leal JF; Blanco-Aparicio C; Romero L; Sánchez-Beato M; Cigudosa JC; Tercero JC; Piris MA; Jimeno J; Carnero A
    J Cell Biochem; 2007 Feb; 100(2):339-48. PubMed ID: 16888811
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transcriptional signature of Ecteinascidin 743 (Yondelis, Trabectedin) in human sarcoma cells explanted from chemo-naive patients.
    Martínez N; Sánchez-Beato M; Carnero A; Moneo V; Tercero JC; Fernández I; Navarrete M; Jimeno J; Piris MA
    Mol Cancer Ther; 2005 May; 4(5):814-23. PubMed ID: 15897246
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Trabectedin (ET-743): evaluation of its use in advanced soft-tissue sarcoma.
    Schöffski P; Wolter P; Clement P; Sciot R; De Wever I; Wozniak A; Stefan C; Dumez H
    Future Oncol; 2007 Aug; 3(4):381-92. PubMed ID: 17661712
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sensitivity of soft tissue sarcoma cell lines to chemotherapeutic agents: identification of ecteinascidin-743 as a potent cytotoxic agent.
    Li WW; Takahashi N; Jhanwar S; Cordon-Cardo C; Elisseyeff Y; Jimeno J; Faircloth G; Bertino JR
    Clin Cancer Res; 2001 Sep; 7(9):2908-11. PubMed ID: 11555609
    [TBL] [Abstract][Full Text] [Related]  

  • 5. RG7112, a small-molecule inhibitor of MDM2, enhances trabectedin response in soft tissue sarcomas.
    Obrador-Hevia A; Martinez-Font E; Felipe-Abrio I; Calabuig-Fariñas S; Serra-Sitjar M; López-Guerrero JA; Ramos R; Alemany R; Martín-Broto J
    Cancer Invest; 2015; 33(9):440-50. PubMed ID: 26288114
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 13 years of trabectedin, 5 years of Yondelis®: what have we learnt?
    Le Cesne A
    Expert Rev Anticancer Ther; 2013 Jun; 13(6 Suppl 1):11-9. PubMed ID: 23638726
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Trabectedin is a promising antitumour agent for synovial sarcoma.
    Yasui H; Imura Y; Outani H; Hamada K; Nakai T; Yamada S; Takenaka S; Sasagawa S; Araki N; Itoh K; Myoui A; Yoshikawa H; Naka N
    J Chemother; 2016 Oct; 28(5):417-24. PubMed ID: 27077926
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hyperthermia adds to trabectedin effectiveness and thermal enhancement is associated with BRCA2 degradation and impairment of DNA homologous recombination repair.
    Harnicek D; Kampmann E; Lauber K; Hennel R; Cardoso Martins AS; Guo Y; Belka C; Mörtl S; Gallmeier E; Kanaar R; Mansmann U; Hucl T; Lindner LH; Hiddemann W; Issels RD
    Int J Cancer; 2016 Jul; 139(2):467-79. PubMed ID: 26933761
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ZNF93 increases resistance to ET-743 (Trabectedin; Yondelis) and PM00104 (Zalypsis) in human cancer cell lines.
    Duan Z; Choy E; Harmon D; Yang C; Ryu K; Schwab J; Mankin H; Hornicek FJ
    PLoS One; 2009 Sep; 4(9):e6967. PubMed ID: 19742314
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Enhanced G2/M Arrest, Caspase Related Apoptosis and Reduced E-Cadherin Dependent Intercellular Adhesion by Trabectedin in Prostate Cancer Stem Cells.
    Acikgoz E; Guven U; Duzagac F; Uslu R; Kara M; Soner BC; Oktem G
    PLoS One; 2015; 10(10):e0141090. PubMed ID: 26485709
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Trabectedin efficacy in Ewing sarcoma is greatly increased by combination with anti-IGF signaling agents.
    Amaral AT; Garofalo C; Frapolli R; Manara MC; Mancarella C; Uboldi S; Di Giandomenico S; Ordóñez JL; Sevillano V; Malaguarnera R; Picci P; Hassan AB; De Alava E; D'Incalci M; Scotlandi K
    Clin Cancer Res; 2015 Mar; 21(6):1373-82. PubMed ID: 25609059
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Unique features of trabectedin mechanism of action.
    Larsen AK; Galmarini CM; D'Incalci M
    Cancer Chemother Pharmacol; 2016 Apr; 77(4):663-71. PubMed ID: 26666647
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vitro radiosensitisation by trabectedin in human cancer cell lines.
    Romero J; Zapata I; Córdoba S; Jimeno JM; López-Martín JA; Tercero JC; De La Torre A; Vargas JA; Molerón R; Sánchez-Prieto R
    Eur J Cancer; 2008 Aug; 44(12):1726-33. PubMed ID: 18501589
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Trabectedin is a promising antitumor agent potentially inducing melanocytic differentiation for clear cell sarcoma.
    Nakai T; Imura Y; Tamiya H; Yamada S; Nakai S; Yasuda N; Kaneko K; Outani H; Takenaka S; Hamada K; Myoui A; Araki N; Ueda T; Itoh K; Yoshikawa H; Naka N
    Cancer Med; 2017 Sep; 6(9):2121-2130. PubMed ID: 28745431
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Yondelis® (ET-743, Trabectedin) sensitizes cancer cell lines to CD95-mediated cell death: new molecular insight into the mechanism of action.
    Martínez-Serra J; Maffiotte E; Martín J; Bex T; Navarro-Palou M; Ros T; Plazas JM; Vögler O; Gutiérrez A; Amat JC; Ramos R; Saus C; Ginés J; Alemany R; Diaz M; Besalduch J
    Eur J Pharmacol; 2011 May; 658(2-3):57-64. PubMed ID: 21371453
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dynamics of cell cycle phase perturbations by trabectedin (ET-743) in nucleotide excision repair (NER)-deficient and NER-proficient cells, unravelled by a novel mathematical simulation approach.
    Tavecchio M; Natoli C; Ubezio P; Erba E; D'Incalci M
    Cell Prolif; 2007 Dec; 40(6):885-904. PubMed ID: 18021177
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Experience of the use of trabectedin (ET-743, Yondelis) in 21 patients with pre-treated advanced sarcoma from a single centre.
    Roylance R; Seddon B; McTiernan A; Sykes K; Daniels S; Whelan J
    Clin Oncol (R Coll Radiol); 2007 Oct; 19(8):572-6. PubMed ID: 17624747
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Trabectedin (ET-743, Yondelis) is a substrate for P-glycoprotein, but only high expression of P-glycoprotein confers the multidrug resistance phenotype.
    Beumer JH; Buckle T; Ouwehand M; Franke NE; Lopez-Lazaro L; Schellens JH; Beijnen JH; van Tellingen O
    Invest New Drugs; 2007 Feb; 25(1):1-7. PubMed ID: 16633714
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Development of Yondelis (trabectedin, ET-743). A semisynthetic process solves the supply problem.
    Cuevas C; Francesch A
    Nat Prod Rep; 2009 Mar; 26(3):322-37. PubMed ID: 19240944
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Anti-cancer effect and gene modulation of ET-743 in human biliary tract carcinoma preclinical models.
    Peraldo-Neia C; Cavalloni G; Soster M; Gammaitoni L; Marchiò S; Sassi F; Trusolino L; Bertotti A; Medico E; Capussotti L; Aglietta M; Leone F
    BMC Cancer; 2014 Dec; 14():918. PubMed ID: 25479910
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.