536 related articles for article (PubMed ID: 16892081)
1. Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer.
King A; Selak MA; Gottlieb E
Oncogene; 2006 Aug; 25(34):4675-82. PubMed ID: 16892081
[TBL] [Abstract][Full Text] [Related]
2. Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations.
Pollard PJ; Brière JJ; Alam NA; Barwell J; Barclay E; Wortham NC; Hunt T; Mitchell M; Olpin S; Moat SJ; Hargreaves IP; Heales SJ; Chung YL; Griffiths JR; Dalgleish A; McGrath JA; Gleeson MJ; Hodgson SV; Poulsom R; Rustin P; Tomlinson IP
Hum Mol Genet; 2005 Aug; 14(15):2231-9. PubMed ID: 15987702
[TBL] [Abstract][Full Text] [Related]
3. Isocitrate dehydrogenase (IDH), succinate dehydrogenase (SDH), fumarate hydratase (FH): three players for one phenotype in cancer?
Laurenti G; Tennant DA
Biochem Soc Trans; 2016 Aug; 44(4):1111-6. PubMed ID: 27528759
[TBL] [Abstract][Full Text] [Related]
4. Mitochondrial tumour suppressors: a genetic and biochemical update.
Gottlieb E; Tomlinson IP
Nat Rev Cancer; 2005 Nov; 5(11):857-66. PubMed ID: 16327764
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors.
Xiao M; Yang H; Xu W; Ma S; Lin H; Zhu H; Liu L; Liu Y; Yang C; Xu Y; Zhao S; Ye D; Xiong Y; Guan KL
Genes Dev; 2012 Jun; 26(12):1326-38. PubMed ID: 22677546
[TBL] [Abstract][Full Text] [Related]
6. The TCA cycle and tumorigenesis: the examples of fumarate hydratase and succinate dehydrogenase.
Pollard PJ; Wortham NC; Tomlinson IP
Ann Med; 2003; 35(8):632-9. PubMed ID: 14708972
[TBL] [Abstract][Full Text] [Related]
7. A role for mitochondrial enzymes in inherited neoplasia and beyond.
Eng C; Kiuru M; Fernandez MJ; Aaltonen LA
Nat Rev Cancer; 2003 Mar; 3(3):193-202. PubMed ID: 12612654
[TBL] [Abstract][Full Text] [Related]
8. Inactivation of SDH and FH cause loss of 5hmC and increased H3K9me3 in paraganglioma/pheochromocytoma and smooth muscle tumors.
Hoekstra AS; de Graaff MA; Briaire-de Bruijn IH; Ras C; Seifar RM; van Minderhout I; Cornelisse CJ; Hogendoorn PC; Breuning MH; Suijker J; Korpershoek E; Kunst HP; Frizzell N; Devilee P; Bayley JP; Bovée JV
Oncotarget; 2015 Nov; 6(36):38777-88. PubMed ID: 26472283
[TBL] [Abstract][Full Text] [Related]
9. Mitochondria in cancer.
Kroemer G
Oncogene; 2006 Aug; 25(34):4630-2. PubMed ID: 16892077
[TBL] [Abstract][Full Text] [Related]
10. The role of mutation of metabolism-related genes in genomic hypermethylation.
Waterfall JJ; Killian JK; Meltzer PS
Biochem Biophys Res Commun; 2014 Dec; 455(1-2):16-23. PubMed ID: 25111818
[TBL] [Abstract][Full Text] [Related]
11. Mitochondrial dysfunctions in cancer: genetic defects and oncogenic signaling impinging on TCA cycle activity.
Desideri E; Vegliante R; Ciriolo MR
Cancer Lett; 2015 Jan; 356(2 Pt A):217-23. PubMed ID: 24614286
[TBL] [Abstract][Full Text] [Related]
12. Fumarate hydratase in cancer: A multifaceted tumour suppressor.
Schmidt C; Sciacovelli M; Frezza C
Semin Cell Dev Biol; 2020 Feb; 98():15-25. PubMed ID: 31085323
[TBL] [Abstract][Full Text] [Related]
13. The role of metabolic enzymes in mesenchymal tumors and tumor syndromes: genetics, pathology, and molecular mechanisms.
Schaefer IM; Hornick JL; Bovée JVMG
Lab Invest; 2018 Apr; 98(4):414-426. PubMed ID: 29339836
[TBL] [Abstract][Full Text] [Related]
14. Revisiting the TCA cycle: signaling to tumor formation.
Raimundo N; Baysal BE; Shadel GS
Trends Mol Med; 2011 Nov; 17(11):641-9. PubMed ID: 21764377
[TBL] [Abstract][Full Text] [Related]
15. Cancer. Puzzling patterns of predisposition.
Pollard PJ; Ratcliffe PJ
Science; 2009 Apr; 324(5924):192-4. PubMed ID: 19359573
[No Abstract] [Full Text] [Related]
16. Gerometabolites: the pseudohypoxic aging side of cancer oncometabolites.
Menendez JA; Alarcón T; Joven J
Cell Cycle; 2014; 13(5):699-709. PubMed ID: 24526120
[TBL] [Abstract][Full Text] [Related]
17. Distinct expression profile in fumarate-hydratase-deficient uterine fibroids.
Vanharanta S; Pollard PJ; Lehtonen HJ; Laiho P; Sjöberg J; Leminen A; Aittomäki K; Arola J; Kruhoffer M; Orntoft TF; Tomlinson IP; Kiuru M; Arango D; Aaltonen LA
Hum Mol Genet; 2006 Jan; 15(1):97-103. PubMed ID: 16319128
[TBL] [Abstract][Full Text] [Related]
18. Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells.
MacKenzie ED; Selak MA; Tennant DA; Payne LJ; Crosby S; Frederiksen CM; Watson DG; Gottlieb E
Mol Cell Biol; 2007 May; 27(9):3282-9. PubMed ID: 17325041
[TBL] [Abstract][Full Text] [Related]
19. Warburg tumours and the mechanisms of mitochondrial tumour suppressor genes. Barking up the right tree?
Bayley JP; Devilee P
Curr Opin Genet Dev; 2010 Jun; 20(3):324-9. PubMed ID: 20304625
[TBL] [Abstract][Full Text] [Related]
20. Targeting cancer metabolism.
Teicher BA; Linehan WM; Helman LJ
Clin Cancer Res; 2012 Oct; 18(20):5537-45. PubMed ID: 23071355
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
