These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

291 related articles for article (PubMed ID: 16894147)

  • 1. The first three domains of the insulin receptor differ structurally from the insulin-like growth factor 1 receptor in the regions governing ligand specificity.
    Lou M; Garrett TP; McKern NM; Hoyne PA; Epa VC; Bentley JD; Lovrecz GO; Cosgrove LJ; Frenkel MJ; Ward CW
    Proc Natl Acad Sci U S A; 2006 Aug; 103(33):12429-34. PubMed ID: 16894147
    [TBL] [Abstract][Full Text] [Related]  

  • 2. [The structural organization of binding determinants in insulin-like growth factor-I (IGF-I) molecule].
    Kolychev AP
    Zh Evol Biokhim Fiziol; 2010; 46(1):74-94. PubMed ID: 20297673
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insulin receptor structure and its implications for the IGF-1 receptor.
    Lawrence MC; McKern NM; Ward CW
    Curr Opin Struct Biol; 2007 Dec; 17(6):699-705. PubMed ID: 17851071
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural Congruency of Ligand Binding to the Insulin and Insulin/Type 1 Insulin-like Growth Factor Hybrid Receptors.
    Menting JG; Lawrence CF; Kong GK; Margetts MB; Ward CW; Lawrence MC
    Structure; 2015 Jul; 23(7):1271-82. PubMed ID: 26027733
    [TBL] [Abstract][Full Text] [Related]  

  • 5. How IGF-1 activates its receptor.
    Kavran JM; McCabe JM; Byrne PO; Connacher MK; Wang Z; Ramek A; Sarabipour S; Shan Y; Shaw DE; Hristova K; Cole PA; Leahy DJ
    Elife; 2014 Sep; 3():. PubMed ID: 25255214
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural insights into ligand-induced activation of the insulin receptor.
    Ward C; Lawrence M; Streltsov V; Garrett T; McKern N; Lou MZ; Lovrecz G; Adams T
    Acta Physiol (Oxf); 2008 Jan; 192(1):3-9. PubMed ID: 18171424
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Solution structure of ectodomains of the insulin receptor family: the ectodomain of the type 1 insulin-like growth factor receptor displays asymmetry of ligand binding accompanied by limited conformational change.
    Whitten AE; Smith BJ; Menting JG; Margetts MB; McKern NM; Lovrecz GO; Adams TE; Richards K; Bentley JD; Trewhella J; Ward CW; Lawrence MC
    J Mol Biol; 2009 Dec; 394(5):878-92. PubMed ID: 19835884
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Crystal structure of the first three domains of the type-1 insulin-like growth factor receptor.
    Garrett TP; McKern NM; Lou M; Frenkel MJ; Bentley JD; Lovrecz GO; Elleman TC; Cosgrove LJ; Ward CW
    Nature; 1998 Jul; 394(6691):395-9. PubMed ID: 9690478
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A single-chain insulin-like growth factor I/insulin hybrid binds with high affinity to the insulin receptor.
    Kristensen C; Andersen AS; Hach M; Wiberg FC; Schäffer L; Kjeldsen T
    Biochem J; 1995 Feb; 305 ( Pt 3)(Pt 3):981-6. PubMed ID: 7848300
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ligand-induced activation of the insulin receptor: a multi-step process involving structural changes in both the ligand and the receptor.
    Ward CW; Lawrence MC
    Bioessays; 2009 Apr; 31(4):422-34. PubMed ID: 19274663
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of insulin/IGF hybrid receptors: contributions of the insulin receptor L2 and Fn1 domains and the alternatively spliced exon 11 sequence to ligand binding and receptor activation.
    Benyoucef S; Surinya KH; Hadaschik D; Siddle K
    Biochem J; 2007 May; 403(3):603-13. PubMed ID: 17291192
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cys 786 and Cys 776 in the posttranslational processing of the insulin and IGF-I receptors.
    Maggi D; Cordera R
    Biochem Biophys Res Commun; 2001 Jan; 280(3):836-41. PubMed ID: 11162597
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular mechanisms underlying insulin-like growth factor action: How mutations in the GH: IGF axis lead to short stature.
    Forbes BE
    Pediatr Endocrinol Rev; 2011 Jun; 8(4):374-81. PubMed ID: 21972777
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Specificity in ligand binding and intracellular signalling by insulin and insulin-like growth factor receptors.
    Siddle K; Ursø B; Niesler CA; Cope DL; Molina L; Surinya KH; Soos MA
    Biochem Soc Trans; 2001 Aug; 29(Pt 4):513-25. PubMed ID: 11498020
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutations at hypothetical binding site 2 in insulin and insulin-like growth factors 1 and 2 result in receptor- and hormone-specific responses.
    Macháčková K; Mlčochová K; Potalitsyn P; Hanková K; Socha O; Buděšínský M; Muždalo A; Lepšík M; Černeková M; Radosavljević J; Fábry M; Mitrová K; Chrudinová M; Lin J; Yurenko Y; Hobza P; Selicharová I; Žáková L; Jiráček J
    J Biol Chem; 2019 Nov; 294(46):17371-17382. PubMed ID: 31558604
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An investigation of the ligand binding properties and negative cooperativity of soluble insulin-like growth factor receptors.
    Surinya KH; Forbes BE; Occhiodoro F; Booker GW; Francis GL; Siddle K; Wallace JC; Cosgrove LJ
    J Biol Chem; 2008 Feb; 283(9):5355-63. PubMed ID: 18056713
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A peptide derived from an extracellular domain selectively inhibits receptor internalization: target sequences on insulin and insulin-like growth factor 1 receptors.
    Naranda T; Goldstein A; Olsson L
    Proc Natl Acad Sci U S A; 1997 Oct; 94(21):11692-7. PubMed ID: 9326672
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Understanding the mechanism of insulin and insulin-like growth factor (IGF) receptor activation by IGF-II.
    Alvino CL; Ong SC; McNeil KA; Delaine C; Booker GW; Wallace JC; Forbes BE
    PLoS One; 2011; 6(11):e27488. PubMed ID: 22140443
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A thermodynamic study of ligand binding to the first three domains of the human insulin receptor: relationship between the receptor alpha-chain C-terminal peptide and the site 1 insulin mimetic peptides.
    Menting JG; Ward CW; Margetts MB; Lawrence MC
    Biochemistry; 2009 Jun; 48(23):5492-500. PubMed ID: 19459609
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cryo-EM structure shows how two IGF1 hormones bind to the human IGF1R receptor.
    Wu C; Huang X; Dong F; Tang W; Shi J; Lu X; Shu Q; Zhang X
    Biochem Biophys Res Commun; 2022 Dec; 636(Pt 1):121-124. PubMed ID: 36332473
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.