These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

436 related articles for article (PubMed ID: 16895439)

  • 1. Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion.
    Bijlsma MF; Spek CA; Zivkovic D; van de Water S; Rezaee F; Peppelenbosch MP
    PLoS Biol; 2006 Jul; 4(8):e232. PubMed ID: 16895439
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Adenovirus vector-mediated Gli1 siRNA induces growth inhibition and apoptosis in human pancreatic cancer with Smo-dependent or Smo-independent Hh pathway activation in vitro and in vivo.
    Guo J; Gao J; Li Z; Gong Y; Man X; Jin J; Wu H
    Cancer Lett; 2013 Oct; 339(2):185-94. PubMed ID: 23791879
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hedgehog-signaling is upregulated in non-producing human adrenal adenomas and antagonism of hedgehog-signaling inhibits proliferation of NCI-H295R cells and an immortalized primary human adrenal cell line.
    Werminghaus P; Haase M; Hornsby PJ; Schinner S; Schott M; Malendowicz LK; Lammers BJ; Goretzki PE; Müller-Mattheis V; Markus Giessing ; Willenberg HS
    J Steroid Biochem Mol Biol; 2014 Jan; 139():7-15. PubMed ID: 24063979
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Gastric cancer (GC) patients with hedgehog pathway activation: PTCH1 and GLI2 as independent prognostic factors.
    Lee SJ; Do IG; Lee J; Kim KM; Jang J; Sohn I; Kang WK
    Target Oncol; 2013 Dec; 8(4):271-80. PubMed ID: 23371028
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of Erk by sonic hedgehog independent of canonical hedgehog signalling.
    Chang H; Li Q; Moraes RC; Lewis MT; Hamel PA
    Int J Biochem Cell Biol; 2010 Sep; 42(9):1462-71. PubMed ID: 20451654
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ptch2 mediates the Shh response in Ptch1-/- cells.
    Alfaro AC; Roberts B; Kwong L; Bijlsma MF; Roelink H
    Development; 2014 Sep; 141(17):3331-9. PubMed ID: 25085974
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury.
    Grzelak CA; Martelotto LG; Sigglekow ND; Patkunanathan B; Ajami K; Calabro SR; Dwyer BJ; Tirnitz-Parker JE; Watkins DN; Warner FJ; Shackel NA; McCaughan GW
    J Hepatol; 2014 Jan; 60(1):143-51. PubMed ID: 23978713
    [TBL] [Abstract][Full Text] [Related]  

  • 8. All-trans-retinoic acid antagonizes the Hedgehog pathway by inducing patched.
    Busch AM; Galimberti F; Nehls KE; Roengvoraphoj M; Sekula D; Li B; Guo Y; Direnzo J; Fiering SN; Spinella MJ; Robbins DJ; Memoli VA; Freemantle SJ; Dmitrovsky E
    Cancer Biol Ther; 2014 Apr; 15(4):463-72. PubMed ID: 24496080
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The hedgehog-patched signaling pathway and function in the mammalian ovary: a novel role for hedgehog proteins in stimulating proliferation and steroidogenesis of theca cells.
    Spicer LJ; Sudo S; Aad PY; Wang LS; Chun SY; Ben-Shlomo I; Klein C; Hsueh AJ
    Reproduction; 2009 Aug; 138(2):329-39. PubMed ID: 19433502
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ptch2 shares overlapping functions with Ptch1 in Smo regulation and limb development.
    Zhulyn O; Nieuwenhuis E; Liu YC; Angers S; Hui CC
    Dev Biol; 2015 Jan; 397(2):191-202. PubMed ID: 25448692
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Response to inhibition of smoothened in diverse epithelial cancer cells that lack smoothened or patched 1 mutations.
    Galimberti F; Busch AM; Chinyengetere F; Ma T; Sekula D; Memoli VA; Dragnev KH; Liu F; Johnson KC; Guo Y; Freemantle SJ; Andrew AS; Greninger P; Robbins DJ; Settleman J; Benes C; Dmitrovsky E
    Int J Oncol; 2012 Nov; 41(5):1751-61. PubMed ID: 22923130
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists.
    Frank-Kamenetsky M; Zhang XM; Bottega S; Guicherit O; Wichterle H; Dudek H; Bumcrot D; Wang FY; Jones S; Shulok J; Rubin LL; Porter JA
    J Biol; 2002 Nov; 1(2):10. PubMed ID: 12437772
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sonic Hedgehog activates the GTPases Rac1 and RhoA in a Gli-independent manner through coupling of smoothened to Gi proteins.
    Polizio AH; Chinchilla P; Chen X; Manning DR; Riobo NA
    Sci Signal; 2011 Nov; 4(200):pt7. PubMed ID: 22114142
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression of the PTCH1 tumor suppressor gene is regulated by alternative promoters and a single functional Gli-binding site.
    Agren M; Kogerman P; Kleman MI; Wessling M; Toftgård R
    Gene; 2004 Apr; 330():101-14. PubMed ID: 15087129
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Trisomy 12 and elevated GLI1 and PTCH1 transcript levels are biomarkers for Hedgehog-inhibitor responsiveness in CLL.
    Decker S; Zirlik K; Djebatchie L; Hartmann D; Ihorst G; Schmitt-Graeff A; Herchenbach D; Jumaa H; Warmuth M; Veelken H; Dierks C
    Blood; 2012 Jan; 119(4):997-1007. PubMed ID: 22130798
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Patched1 and Patched2 inhibit Smoothened non-cell autonomously.
    Roberts B; Casillas C; Alfaro AC; Jägers C; Roelink H
    Elife; 2016 Aug; 5():. PubMed ID: 27552050
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Distinct roles of PTCH2 splice variants in Hedgehog signalling.
    Rahnama F; Toftgård R; Zaphiropoulos PG
    Biochem J; 2004 Mar; 378(Pt 2):325-34. PubMed ID: 14613484
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sonic hedgehog signaling by the patched-smoothened receptor complex.
    Murone M; Rosenthal A; de Sauvage FJ
    Curr Biol; 1999 Jan; 9(2):76-84. PubMed ID: 10021362
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Overexpression of hedgehog pathway molecules and FOXM1 in non-small cell lung carcinomas.
    Gialmanidis IP; Bravou V; Amanetopoulou SG; Varakis J; Kourea H; Papadaki H
    Lung Cancer; 2009 Oct; 66(1):64-74. PubMed ID: 19200615
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Smoothened transduces Hedgehog signal by forming a complex with Evc/Evc2.
    Yang C; Chen W; Chen Y; Jiang J
    Cell Res; 2012 Nov; 22(11):1593-604. PubMed ID: 22986504
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.