BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

228 related articles for article (PubMed ID: 16896941)

  • 1. BCL-6: a possible missing link for anti-inflammatory PPAR-delta signalling in pancreatic beta cells.
    Kharroubi I; Lee CH; Hekerman P; Darville MI; Evans RM; Eizirik DL; Cnop M
    Diabetologia; 2006 Oct; 49(10):2350-8. PubMed ID: 16896941
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of lipid peroxidation and PPAR-δ in amplifying glucose-stimulated insulin secretion.
    Cohen G; Riahi Y; Shamni O; Guichardant M; Chatgilialoglu C; Ferreri C; Kaiser N; Sasson S
    Diabetes; 2011 Nov; 60(11):2830-42. PubMed ID: 21896929
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of PPARβ/δ protects pancreatic β cells from palmitate-induced apoptosis by upregulating the expression of GLP-1 receptor.
    Yang Y; Tong Y; Gong M; Lu Y; Wang C; Zhou M; Yang Q; Mao T; Tong N
    Cell Signal; 2014 Feb; 26(2):268-78. PubMed ID: 24269940
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of peroxisome proliferator-activated receptor beta/delta inhibits lipopolysaccharide-induced cytokine production in adipocytes by lowering nuclear factor-kappaB activity via extracellular signal-related kinase 1/2.
    Rodríguez-Calvo R; Serrano L; Coll T; Moullan N; Sánchez RM; Merlos M; Palomer X; Laguna JC; Michalik L; Wahli W; Vázquez-Carrera M
    Diabetes; 2008 Aug; 57(8):2149-57. PubMed ID: 18443198
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of peroxisome proliferator-activated receptor-gamma protects pancreatic beta-cells from cytokine-induced cytotoxicity via NF kappaB pathway.
    Kim EK; Kwon KB; Koo BS; Han MJ; Song MY; Song EK; Han MK; Park JW; Ryu DG; Park BH
    Int J Biochem Cell Biol; 2007; 39(6):1260-75. PubMed ID: 17521952
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Induction of nuclear factor-kappaB and its downstream genes by TNF-alpha and IL-1beta has a pro-apoptotic role in pancreatic beta cells.
    Ortis F; Pirot P; Naamane N; Kreins AY; Rasschaert J; Moore F; Théâtre E; Verhaeghe C; Magnusson NE; Chariot A; Orntoft TF; Eizirik DL
    Diabetologia; 2008 Jul; 51(7):1213-25. PubMed ID: 18463842
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The non-canonical NF-κB pathway is induced by cytokines in pancreatic beta cells and contributes to cell death and proinflammatory responses in vitro.
    Meyerovich K; Fukaya M; Terra LF; Ortis F; Eizirik DL; Cardozo AK
    Diabetologia; 2016 Mar; 59(3):512-21. PubMed ID: 26634571
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The peroxisome proliferator-activated receptor (PPAR) β/δ agonist GW501516 inhibits IL-6-induced signal transducer and activator of transcription 3 (STAT3) activation and insulin resistance in human liver cells.
    Serrano-Marco L; Barroso E; El Kochairi I; Palomer X; Michalik L; Wahli W; Vázquez-Carrera M
    Diabetologia; 2012 Mar; 55(3):743-51. PubMed ID: 22179221
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cytokine-induced proapoptotic gene expression in insulin-producing cells is related to rapid, sustained, and nonoscillatory nuclear factor-kappaB activation.
    Ortis F; Cardozo AK; Crispim D; Störling J; Mandrup-Poulsen T; Eizirik DL
    Mol Endocrinol; 2006 Aug; 20(8):1867-79. PubMed ID: 16556731
    [TBL] [Abstract][Full Text] [Related]  

  • 10. IL-1beta-induced chemokine and Fas expression are inhibited by suppressor of cytokine signalling-3 in insulin-producing cells.
    Jacobsen ML; Rønn SG; Bruun C; Larsen CM; Eizirik DL; Mandrup-Poulsen T; Billestrup N
    Diabetologia; 2009 Feb; 52(2):281-8. PubMed ID: 19002429
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activated PPARβ/δ Protects Pancreatic β Cells in Type 2 Diabetic Goto-Kakizaki Rats from Lipoapoptosis via GPR40.
    Li J; Xu S; Liu Y; Yan Z; Zhang F; Lv Q; Tong N
    Lipids; 2019 Oct; 54(10):603-616. PubMed ID: 31364177
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Irisin Ameliorates Glucolipotoxicity-Associated β-Cell Dysfunction and Apoptosis via AMPK Signaling and Anti-Inflammatory Actions.
    Zhang D; Xie T; Leung PS
    Cell Physiol Biochem; 2018; 51(2):924-937. PubMed ID: 30466091
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The peroxisome proliferator-activated receptor β/δ (PPARβ/δ) agonist GW501516 prevents TNF-α-induced NF-κB activation in human HaCaT cells by reducing p65 acetylation through AMPK and SIRT1.
    Barroso E; Eyre E; Palomer X; Vázquez-Carrera M
    Biochem Pharmacol; 2011 Feb; 81(4):534-43. PubMed ID: 21146504
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of peroxisome proliferator-activated receptor-β/-δ (PPAR-β/-δ) ameliorates insulin signaling and reduces SOCS3 levels by inhibiting STAT3 in interleukin-6-stimulated adipocytes.
    Serrano-Marco L; Rodríguez-Calvo R; El Kochairi I; Palomer X; Michalik L; Wahli W; Vázquez-Carrera M
    Diabetes; 2011 Jul; 60(7):1990-9. PubMed ID: 21617181
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cytokine-mediated induction of anti-apoptotic genes that are linked to nuclear factor kappa-B (NF-kappaB) signalling in human islets and in a mouse beta cell line.
    Sarkar SA; Kutlu B; Velmurugan K; Kizaka-Kondoh S; Lee CE; Wong R; Valentine A; Davidson HW; Hutton JC; Pugazhenthi S
    Diabetologia; 2009 Jun; 52(6):1092-101. PubMed ID: 19343319
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cells.
    Moore F; Santin I; Nogueira TC; Gurzov EN; Marselli L; Marchetti P; Eizirik DL
    PLoS One; 2012; 7(2):e31062. PubMed ID: 22347430
    [TBL] [Abstract][Full Text] [Related]  

  • 17. IL-1beta-induced pro-apoptotic signalling is facilitated by NCAM/FGF receptor signalling and inhibited by the C3d ligand in the INS-1E rat beta cell line.
    Petersen LG; Størling J; Heding P; Li S; Berezin V; Saldeen J; Billestrup N; Bock E; Mandrup-Poulsen T
    Diabetologia; 2006 Aug; 49(8):1864-75. PubMed ID: 16718462
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interferon regulatory factor-1 is a key transcription factor in murine beta cells under immune attack.
    Gysemans C; Callewaert H; Moore F; Nelson-Holte M; Overbergh L; Eizirik DL; Mathieu C
    Diabetologia; 2009 Nov; 52(11):2374-2384. PubMed ID: 19756487
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPARdelta agonist, on development of steatohepatitis in mice fed a methionine- and choline-deficient diet.
    Nagasawa T; Inada Y; Nakano S; Tamura T; Takahashi T; Maruyama K; Yamazaki Y; Kuroda J; Shibata N
    Eur J Pharmacol; 2006 Apr; 536(1-2):182-91. PubMed ID: 16574099
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PPAR-γ activation restores pancreatic islet SERCA2 levels and prevents β-cell dysfunction under conditions of hyperglycemic and cytokine stress.
    Kono T; Ahn G; Moss DR; Gann L; Zarain-Herzberg A; Nishiki Y; Fueger PT; Ogihara T; Evans-Molina C
    Mol Endocrinol; 2012 Feb; 26(2):257-71. PubMed ID: 22240811
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.