251 related articles for article (PubMed ID: 16905097)
1. Insights into the sirtuin mechanism from ternary complexes containing NAD+ and acetylated peptide.
Hoff KG; Avalos JL; Sens K; Wolberger C
Structure; 2006 Aug; 14(8):1231-40. PubMed ID: 16905097
[TBL] [Abstract][Full Text] [Related]
2. Substrate specificity and kinetic mechanism of the Sir2 family of NAD+-dependent histone/protein deacetylases.
Borra MT; Langer MR; Slama JT; Denu JM
Biochemistry; 2004 Aug; 43(30):9877-87. PubMed ID: 15274642
[TBL] [Abstract][Full Text] [Related]
3. The structural basis of sirtuin substrate affinity.
Cosgrove MS; Bever K; Avalos JL; Muhammad S; Zhang X; Wolberger C
Biochemistry; 2006 Jun; 45(24):7511-21. PubMed ID: 16768447
[TBL] [Abstract][Full Text] [Related]
4. One-step, nonenzymatic synthesis of O-acetyl-ADP-ribose and analogues from NAD and carboxylates.
Szczepankiewicz BG; Koppetsch KJ; Perni RB
J Org Chem; 2011 Aug; 76(16):6465-74. PubMed ID: 21639110
[TBL] [Abstract][Full Text] [Related]
5. The Sir 2 family of protein deacetylases.
Denu JM
Curr Opin Chem Biol; 2005 Oct; 9(5):431-40. PubMed ID: 16122969
[TBL] [Abstract][Full Text] [Related]
6. Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD(+)-dependent Sir2 histone/protein deacetylases.
Zhao K; Harshaw R; Chai X; Marmorstein R
Proc Natl Acad Sci U S A; 2004 Jun; 101(23):8563-8. PubMed ID: 15150415
[TBL] [Abstract][Full Text] [Related]
7. Mechanism-based inhibition of Sir2 deacetylases by thioacetyl-lysine peptide.
Smith BC; Denu JM
Biochemistry; 2007 Dec; 46(50):14478-86. PubMed ID: 18027980
[TBL] [Abstract][Full Text] [Related]
8. Sir2 regulation by nicotinamide results from switching between base exchange and deacetylation chemistry.
Sauve AA; Schramm VL
Biochemistry; 2003 Aug; 42(31):9249-56. PubMed ID: 12899610
[TBL] [Abstract][Full Text] [Related]
9. Structural insights into intermediate steps in the Sir2 deacetylation reaction.
Hawse WF; Hoff KG; Fatkins DG; Daines A; Zubkova OV; Schramm VL; Zheng W; Wolberger C
Structure; 2008 Sep; 16(9):1368-77. PubMed ID: 18786399
[TBL] [Abstract][Full Text] [Related]
10. Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme.
Avalos JL; Bever KM; Wolberger C
Mol Cell; 2005 Mar; 17(6):855-68. PubMed ID: 15780941
[TBL] [Abstract][Full Text] [Related]
11. Structure and substrate binding properties of cobB, a Sir2 homolog protein deacetylase from Escherichia coli.
Zhao K; Chai X; Marmorstein R
J Mol Biol; 2004 Mar; 337(3):731-41. PubMed ID: 15019790
[TBL] [Abstract][Full Text] [Related]
12. Synthesis of carba-NAD and the structures of its ternary complexes with SIRT3 and SIRT5.
Szczepankiewicz BG; Dai H; Koppetsch KJ; Qian D; Jiang F; Mao C; Perni RB
J Org Chem; 2012 Sep; 77(17):7319-29. PubMed ID: 22849721
[TBL] [Abstract][Full Text] [Related]
13. The biochemistry of sirtuins.
Sauve AA; Wolberger C; Schramm VL; Boeke JD
Annu Rev Biochem; 2006; 75():435-65. PubMed ID: 16756498
[TBL] [Abstract][Full Text] [Related]
14. Structural basis of inhibition of the human NAD+-dependent deacetylase SIRT5 by suramin.
Schuetz A; Min J; Antoshenko T; Wang CL; Allali-Hassani A; Dong A; Loppnau P; Vedadi M; Bochkarev A; Sternglanz R; Plotnikov AN
Structure; 2007 Mar; 15(3):377-89. PubMed ID: 17355872
[TBL] [Abstract][Full Text] [Related]
15. Structure-activity studies on suramin analogues as inhibitors of NAD+-dependent histone deacetylases (sirtuins).
Trapp J; Meier R; Hongwiset D; Kassack MU; Sippl W; Jung M
ChemMedChem; 2007 Oct; 2(10):1419-31. PubMed ID: 17628866
[TBL] [Abstract][Full Text] [Related]
16. Splicing regulates NAD metabolite binding to histone macroH2A.
Kustatscher G; Hothorn M; Pugieux C; Scheffzek K; Ladurner AG
Nat Struct Mol Biol; 2005 Jul; 12(7):624-5. PubMed ID: 15965484
[TBL] [Abstract][Full Text] [Related]
17. Sir2 protein deacetylases: evidence for chemical intermediates and functions of a conserved histidine.
Smith BC; Denu JM
Biochemistry; 2006 Jan; 45(1):272-82. PubMed ID: 16388603
[TBL] [Abstract][Full Text] [Related]
18. Investigating the ADP-ribosyltransferase activity of sirtuins with NAD analogues and 32P-NAD.
Du J; Jiang H; Lin H
Biochemistry; 2009 Apr; 48(13):2878-90. PubMed ID: 19220062
[TBL] [Abstract][Full Text] [Related]
19. Small molecule regulation of Sir2 protein deacetylases.
Grubisha O; Smith BC; Denu JM
FEBS J; 2005 Sep; 272(18):4607-16. PubMed ID: 16156783
[TBL] [Abstract][Full Text] [Related]
20. Sirtuin mechanism and inhibition: explored with N(ε)-acetyl-lysine analogs.
Hirsch BM; Zheng W
Mol Biosyst; 2011 Jan; 7(1):16-28. PubMed ID: 20842312
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]