129 related articles for article (PubMed ID: 16908139)
1. Synthesis and HIV-integrase strand transfer inhibition activity of 7-hydroxy[1,3]thiazolo[5,4-b]pyridin-5(4H)-ones.
Boros EE; Johns BA; Garvey EP; Koble CS; Miller WH
Bioorg Med Chem Lett; 2006 Nov; 16(21):5668-72. PubMed ID: 16908139
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and antiviral activity of 7-benzyl-4-hydroxy-1,5-naphthyridin-2(1H)-one HIV integrase inhibitors.
Boros EE; Edwards CE; Foster SA; Fuji M; Fujiwara T; Garvey EP; Golden PL; Hazen RJ; Jeffrey JL; Johns BA; Kawasuji T; Kiyama R; Koble CS; Kurose N; Miller WH; Mote AL; Murai H; Sato A; Thompson JB; Woodward MC; Yoshinaga T
J Med Chem; 2009 May; 52(9):2754-61. PubMed ID: 19374386
[TBL] [Abstract][Full Text] [Related]
3. 3-Hydroxy-4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylates--a new class of HIV-1 integrase inhibitors.
Donghi M; Kinzel OD; Summa V
Bioorg Med Chem Lett; 2009 Apr; 19(7):1930-4. PubMed ID: 19269170
[TBL] [Abstract][Full Text] [Related]
4. Synthesis of 5-(1-H or 1-alkyl-5-oxopyrrolidin-3-yl)-8-hydroxy-[1,6]-naphthyridine-7-carboxamide inhibitors of HIV-1 integrase.
Melamed JY; Egbertson MS; Varga S; Vacca JP; Moyer G; Gabryelski L; Felock PJ; Stillmock KA; Witmer MV; Schleif W; Hazuda DJ; Leonard Y; Jin L; Ellis JD; Young SD
Bioorg Med Chem Lett; 2008 Oct; 18(19):5307-10. PubMed ID: 18774711
[TBL] [Abstract][Full Text] [Related]
5. Design and synthesis of substituted 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamides, novel HIV-1 integrase inhibitors.
Langford HM; Williams PD; Homnick CF; Vacca JP; Felock PJ; Stillmock KA; Witmer MV; Hazuda DJ; Gabryelski LJ; Schleif WA
Bioorg Med Chem Lett; 2008 Jan; 18(2):721-5. PubMed ID: 18078751
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis, and biological evaluation of novel tricyclic HIV-1 integrase inhibitors by modification of its pyridine ring.
Metobo SE; Jin H; Tsiang M; Kim CU
Bioorg Med Chem Lett; 2006 Aug; 16(15):3985-8. PubMed ID: 16723226
[TBL] [Abstract][Full Text] [Related]
7. Design and synthesis of novel nitrogen-containing polyhydroxylated aromatics as HIV-1 integrase inhibitors from caffeic acid phenethyl ester.
Wang P; Liu C; Sanches T; Zhong Y; Liu B; Xiong J; Neamati N; Zhao G
Bioorg Med Chem Lett; 2009 Aug; 19(16):4574-8. PubMed ID: 19625188
[TBL] [Abstract][Full Text] [Related]
8. 8-Hydroxy-3,4-dihydropyrrolo[1,2-a]pyrazine-1(2H)-one HIV-1 integrase inhibitors.
Fisher TE; Kim B; Staas DD; Lyle TA; Young SD; Vacca JP; Zrada MM; Hazuda DJ; Felock PJ; Schleif WA; Gabryelski LJ; Anari MR; Kochansky CJ; Wai JS
Bioorg Med Chem Lett; 2007 Dec; 17(23):6511-5. PubMed ID: 17931865
[TBL] [Abstract][Full Text] [Related]
9. Dihydroxypyrimidine-4-carboxamides as novel potent and selective HIV integrase inhibitors.
Pace P; Di Francesco ME; Gardelli C; Harper S; Muraglia E; Nizi E; Orvieto F; Petrocchi A; Poma M; Rowley M; Scarpelli R; Laufer R; Gonzalez Paz O; Monteagudo E; Bonelli F; Hazuda D; Stillmock KA; Summa V
J Med Chem; 2007 May; 50(9):2225-39. PubMed ID: 17428043
[TBL] [Abstract][Full Text] [Related]
10. 4-Hydroxy-5-pyrrolinone-3-carboxamide HIV-1 integrase inhibitors.
Pace P; Spieser SA; Summa V
Bioorg Med Chem Lett; 2008 Jul; 18(14):3865-9. PubMed ID: 18595690
[TBL] [Abstract][Full Text] [Related]
11. Investigations on the 4-quinolone-3-carboxylic acid motif. 1. Synthesis and structure-activity relationship of a class of human immunodeficiency virus type 1 integrase inhibitors.
Pasquini S; Mugnaini C; Tintori C; Botta M; Trejos A; Arvela RK; Larhed M; Witvrouw M; Michiels M; Christ F; Debyser Z; Corelli F
J Med Chem; 2008 Aug; 51(16):5125-9. PubMed ID: 18665580
[TBL] [Abstract][Full Text] [Related]
12. Effect of substitution on novel tricyclic HIV-1 integrase inhibitors.
Fardis M; Jin H; Jabri S; Cai RZ; Mish M; Tsiang M; Kim CU
Bioorg Med Chem Lett; 2006 Aug; 16(15):4031-5. PubMed ID: 16716589
[TBL] [Abstract][Full Text] [Related]
13. A series of 5-aminosubstituted 4-fluorobenzyl-8-hydroxy-[1,6]naphthyridine-7-carboxamide HIV-1 integrase inhibitors.
Guare JP; Wai JS; Gomez RP; Anthony NJ; Jolly SM; Cortes AR; Vacca JP; Felock PJ; Stillmock KA; Schleif WA; Moyer G; Gabryelski LJ; Jin L; Chen IW; Hazuda DJ; Young SD
Bioorg Med Chem Lett; 2006 Jun; 16(11):2900-4. PubMed ID: 16554152
[TBL] [Abstract][Full Text] [Related]
14. Rationally designed dual inhibitors of HIV reverse transcriptase and integrase.
Wang Z; Bennett EM; Wilson DJ; Salomon C; Vince R
J Med Chem; 2007 Jul; 50(15):3416-9. PubMed ID: 17608468
[TBL] [Abstract][Full Text] [Related]
15. 3-Hydroxy-1,5-dihydro-pyrrol-2-one derivatives as advanced inhibitors of HIV integrase.
Kawasuji T; Fuji M; Yoshinaga T; Sato A; Fujiwara T; Kiyama R
Bioorg Med Chem; 2007 Aug; 15(16):5487-92. PubMed ID: 17560110
[TBL] [Abstract][Full Text] [Related]
16. A series of 5-(5,6)-dihydrouracil substituted 8-hydroxy-[1,6]naphthyridine-7-carboxylic acid 4-fluorobenzylamide inhibitors of HIV-1 integrase and viral replication in cells.
Embrey MW; Wai JS; Funk TW; Homnick CF; Perlow DS; Young SD; Vacca JP; Hazuda DJ; Felock PJ; Stillmock KA; Witmer MV; Moyer G; Schleif WA; Gabryelski LJ; Jin L; Chen IW; Ellis JD; Wong BK; Lin JH; Leonard YM; Tsou NN; Zhuang L
Bioorg Med Chem Lett; 2005 Oct; 15(20):4550-4. PubMed ID: 16102965
[TBL] [Abstract][Full Text] [Related]
17. A refined pharmacophore model for HIV-1 integrase inhibitors: Optimization of potency in the 1H-benzylindole series.
De Luca L; Barreca ML; Ferro S; Iraci N; Michiels M; Christ F; Debyser Z; Witvrouw M; Chimirri A
Bioorg Med Chem Lett; 2008 May; 18(9):2891-5. PubMed ID: 18417342
[TBL] [Abstract][Full Text] [Related]
18. Multivariate QSAR study of 4,5-dihydroxypyrimidine carboxamides as HIV-1 integrase inhibitors.
de Melo EB; Ferreira MM
Eur J Med Chem; 2009 Sep; 44(9):3577-83. PubMed ID: 19327872
[TBL] [Abstract][Full Text] [Related]
19. Azaindole hydroxamic acids are potent HIV-1 integrase inhibitors.
Plewe MB; Butler SL; Dress KR; Hu Q; Johnson TW; Kuehler JE; Kuki A; Lam H; Liu W; Nowlin D; Peng Q; Rahavendran SV; Tanis SP; Tran KT; Wang H; Yang A; Zhang J
J Med Chem; 2009 Nov; 52(22):7211-9. PubMed ID: 19873974
[TBL] [Abstract][Full Text] [Related]
20. Anti-HIV agents. III. Synthesis and in vitro anti-HIV activity of novel 1H,3H-thiazolo[3,4-a]imidazo[4,5-b]pyridines.
Chimirri A; Grasso S; Montforte AM; Monforte P; ZappalĂ M
Farmaco; 1994 May; 49(5):345-8. PubMed ID: 8080617
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]