185 related articles for article (PubMed ID: 16908998)
1. Hippocampal spatial memory impairments caused by the familial Alzheimer's disease-linked presenilin 1 M146V mutation.
Sun X; Beglopoulos V; Mattson MP; Shen J
Neurodegener Dis; 2005; 2(1):6-15. PubMed ID: 16908998
[TBL] [Abstract][Full Text] [Related]
2. Conditional inactivation of presenilin 1 prevents amyloid accumulation and temporarily rescues contextual and spatial working memory impairments in amyloid precursor protein transgenic mice.
Saura CA; Chen G; Malkani S; Choi SY; Takahashi RH; Zhang D; Gouras GK; Kirkwood A; Morris RG; Shen J
J Neurosci; 2005 Jul; 25(29):6755-64. PubMed ID: 16033885
[TBL] [Abstract][Full Text] [Related]
3. Amyloid-beta deposition is associated with decreased hippocampal glucose metabolism and spatial memory impairment in APP/PS1 mice.
Sadowski M; Pankiewicz J; Scholtzova H; Ji Y; Quartermain D; Jensen CH; Duff K; Nixon RA; Gruen RJ; Wisniewski T
J Neuropathol Exp Neurol; 2004 May; 63(5):418-28. PubMed ID: 15198121
[TBL] [Abstract][Full Text] [Related]
4. Evidence for the involvement of calbindin D28k in the presenilin 1 model of Alzheimer's disease.
Odero GL; Oikawa K; Glazner KA; Schapansky J; Grossman D; Thiessen JD; Motnenko A; Ge N; Martin M; Glazner GW; Albensi BC
Neuroscience; 2010 Aug; 169(1):532-43. PubMed ID: 20399254
[TBL] [Abstract][Full Text] [Related]
5. APP processing and synaptic plasticity in presenilin-1 conditional knockout mice.
Yu H; Saura CA; Choi SY; Sun LD; Yang X; Handler M; Kawarabayashi T; Younkin L; Fedeles B; Wilson MA; Younkin S; Kandel ER; Kirkwood A; Shen J
Neuron; 2001 Sep; 31(5):713-26. PubMed ID: 11567612
[TBL] [Abstract][Full Text] [Related]
6. Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice.
Dewachter I; Reversé D; Caluwaerts N; Ris L; Kuipéri C; Van den Haute C; Spittaels K; Umans L; Serneels L; Thiry E; Moechars D; Mercken M; Godaux E; Van Leuven F
J Neurosci; 2002 May; 22(9):3445-53. PubMed ID: 11978821
[TBL] [Abstract][Full Text] [Related]
7. CART mitigates oxidative stress and DNA damage in memory deficits of APP/PS1 mice via upregulating β‑amyloid metabolism‑associated enzymes.
Jiang H; Niu F; Zheng Y; Xu Y
Mol Med Rep; 2021 Apr; 23(4):. PubMed ID: 33604684
[TBL] [Abstract][Full Text] [Related]
8. Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1.
Ohno M; Chang L; Tseng W; Oakley H; Citron M; Klein WL; Vassar R; Disterhoft JF
Eur J Neurosci; 2006 Jan; 23(1):251-60. PubMed ID: 16420434
[TBL] [Abstract][Full Text] [Related]
9. Age-related changes in hippocampal AD pathology, actin remodeling proteins and spatial memory behavior of male APP/PS1 mice.
Sun H; Liu M; Sun T; Chen Y; Lan Z; Lian B; Zhao C; Liu Z; Zhang J; Liu Y
Behav Brain Res; 2019 Dec; 376():112182. PubMed ID: 31472195
[TBL] [Abstract][Full Text] [Related]
10. Presenilin transgenic mice as models of Alzheimer's disease.
Elder GA; Gama Sosa MA; De Gasperi R; Dickstein DL; Hof PR
Brain Struct Funct; 2010 Mar; 214(2-3):127-43. PubMed ID: 19921519
[TBL] [Abstract][Full Text] [Related]
11. Cell cycle-driven neuronal apoptosis specifically linked to amyloid peptide Abeta1-42 exposure is not exacerbated in a mouse model of presenilin-1 familial Alzheimer's disease.
Malik B; Currais A; Soriano S
J Neurochem; 2008 Jul; 106(2):912-6. PubMed ID: 18466334
[TBL] [Abstract][Full Text] [Related]
12. Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease.
Steiner H; Capell A; Leimer U; Haass C
Eur Arch Psychiatry Clin Neurosci; 1999; 249(6):266-70. PubMed ID: 10653281
[TBL] [Abstract][Full Text] [Related]
13. Age- and Brain Region-Specific Changes of Glucose Metabolic Disorder, Learning, and Memory Dysfunction in Early Alzheimer's Disease Assessed in APP/PS1 Transgenic Mice Using
Li XY; Men WW; Zhu H; Lei JF; Zuo FX; Wang ZJ; Zhu ZH; Bao XJ; Wang RZ
Int J Mol Sci; 2016 Oct; 17(10):. PubMed ID: 27763550
[TBL] [Abstract][Full Text] [Related]
14. Genetic reductions of beta-site amyloid precursor protein-cleaving enzyme 1 and amyloid-beta ameliorate impairment of conditioned taste aversion memory in 5XFAD Alzheimer's disease model mice.
Devi L; Ohno M
Eur J Neurosci; 2010 Jan; 31(1):110-8. PubMed ID: 20092558
[TBL] [Abstract][Full Text] [Related]
15. Endogenous expression of FAD-linked PS1 impairs proliferation, neuronal differentiation and survival of adult hippocampal progenitors.
Veeraraghavalu K; Choi SH; Zhang X; Sisodia SS
Mol Neurodegener; 2013 Oct; 8():41. PubMed ID: 24138759
[TBL] [Abstract][Full Text] [Related]
16. Alpha-secretase-derived product of beta-amyloid precursor protein is decreased by presenilin 1 mutations linked to familial Alzheimer's disease.
Ancolio K; Marambaud P; Dauch P; Checler F
J Neurochem; 1997 Dec; 69(6):2494-9. PubMed ID: 9375682
[TBL] [Abstract][Full Text] [Related]
17. Formation of tau inclusions in knock-in mice with familial Alzheimer disease (FAD) mutation of presenilin 1 (PS1).
Tanemura K; Chui DH; Fukuda T; Murayama M; Park JM; Akagi T; Tatebayashi Y; Miyasaka T; Kimura T; Hashikawa T; Nakano Y; Kudo T; Takeda M; Takashima A
J Biol Chem; 2006 Feb; 281(8):5037-41. PubMed ID: 16377636
[TBL] [Abstract][Full Text] [Related]
18. Presenilin-1 familial Alzheimer's disease mutation alters hippocampal neurogenesis and memory function in CCL2 null mice.
Kiyota T; Morrison CM; Tu G; Dyavarshetty B; Weir RA; Zhang G; Xiong H; Gendelman HE
Brain Behav Immun; 2015 Oct; 49():311-21. PubMed ID: 26112421
[TBL] [Abstract][Full Text] [Related]
19. Human Presenilin-1 delivered by AAV9 rescues impaired γ-secretase activity, memory deficits, and neurodegeneration in
Montenegro P; Chen P; Kang J; Lee SH; Leone S; Shen J
Proc Natl Acad Sci U S A; 2023 Oct; 120(42):e2306714120. PubMed ID: 37816062
[TBL] [Abstract][Full Text] [Related]
20. Autophagy enhancer carbamazepine alleviates memory deficits and cerebral amyloid-β pathology in a mouse model of Alzheimer's disease.
Li L; Zhang S; Zhang X; Li T; Tang Y; Liu H; Yang W; Le W
Curr Alzheimer Res; 2013 May; 10(4):433-41. PubMed ID: 23305067
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]