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27. Functional MYCN signature predicts outcome of neuroblastoma irrespective of MYCN amplification. Valentijn LJ; Koster J; Haneveld F; Aissa RA; van Sluis P; Broekmans ME; Molenaar JJ; van Nes J; Versteeg R Proc Natl Acad Sci U S A; 2012 Nov; 109(47):19190-5. PubMed ID: 23091029 [TBL] [Abstract][Full Text] [Related]
28. Inhibition of mTOR-kinase destabilizes MYCN and is a potential therapy for MYCN-dependent tumors. Vaughan L; Clarke PA; Barker K; Chanthery Y; Gustafson CW; Tucker E; Renshaw J; Raynaud F; Li X; Burke R; Jamin Y; Robinson SP; Pearson A; Maira M; Weiss WA; Workman P; Chesler L Oncotarget; 2016 Sep; 7(36):57525-57544. PubMed ID: 27438153 [TBL] [Abstract][Full Text] [Related]
29. p53 is a direct transcriptional target of MYCN in neuroblastoma. Chen L; Iraci N; Gherardi S; Gamble LD; Wood KM; Perini G; Lunec J; Tweddle DA Cancer Res; 2010 Feb; 70(4):1377-88. PubMed ID: 20145147 [TBL] [Abstract][Full Text] [Related]
30. ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma. Hogarty MD; Norris MD; Davis K; Liu X; Evageliou NF; Hayes CS; Pawel B; Guo R; Zhao H; Sekyere E; Keating J; Thomas W; Cheng NC; Murray J; Smith J; Sutton R; Venn N; London WB; Buxton A; Gilmour SK; Marshall GM; Haber M Cancer Res; 2008 Dec; 68(23):9735-45. PubMed ID: 19047152 [TBL] [Abstract][Full Text] [Related]
31. MYCN sensitizes neuroblastoma to the MDM2-p53 antagonists Nutlin-3 and MI-63. Gamble LD; Kees UR; Tweddle DA; Lunec J Oncogene; 2012 Feb; 31(6):752-63. PubMed ID: 21725357 [TBL] [Abstract][Full Text] [Related]
32. NCYM promotes calpain-mediated Myc-nick production in human MYCN-amplified neuroblastoma cells. Shoji W; Suenaga Y; Kaneko Y; Islam SM; Alagu J; Yokoi S; Nio M; Nakagawara A Biochem Biophys Res Commun; 2015 Jun; 461(3):501-6. PubMed ID: 25896758 [TBL] [Abstract][Full Text] [Related]
33. GSK3 inhibitors regulate MYCN mRNA levels and reduce neuroblastoma cell viability through multiple mechanisms, including p53 and Wnt signaling. Duffy DJ; Krstic A; Schwarzl T; Higgins DG; Kolch W Mol Cancer Ther; 2014 Feb; 13(2):454-67. PubMed ID: 24282277 [TBL] [Abstract][Full Text] [Related]
34. Crosstalk between MYCN and MDM2-p53 signal pathways regulates tumor cell growth and apoptosis in neuroblastoma. He J; Gu L; Zhang H; Zhou M Cell Cycle; 2011 Sep; 10(17):2994-3002. PubMed ID: 21862876 [TBL] [Abstract][Full Text] [Related]
35. Cellular retinoic acid-binding protein II is a direct transcriptional target of MycN in neuroblastoma. Gupta A; Williams BR; Hanash SM; Rawwas J Cancer Res; 2006 Aug; 66(16):8100-8. PubMed ID: 16912187 [TBL] [Abstract][Full Text] [Related]
36. MYCN silencing induces differentiation and apoptosis in human neuroblastoma cells. Kang JH; Rychahou PG; Ishola TA; Qiao J; Evers BM; Chung DH Biochem Biophys Res Commun; 2006 Dec; 351(1):192-7. PubMed ID: 17055458 [TBL] [Abstract][Full Text] [Related]
37. Key role for p27Kip1, retinoblastoma protein Rb, and MYCN in polyamine inhibitor-induced G1 cell cycle arrest in MYCN-amplified human neuroblastoma cells. Wallick CJ; Gamper I; Thorne M; Feith DJ; Takasaki KY; Wilson SM; Seki JA; Pegg AE; Byus CV; Bachmann AS Oncogene; 2005 Aug; 24(36):5606-18. PubMed ID: 16007177 [TBL] [Abstract][Full Text] [Related]
38. TWIST1 is a direct transcriptional target of MYCN and MYC in neuroblastoma. Selmi A; de Saint-Jean M; Jallas AC; Garin E; Hogarty MD; Bénard J; Puisieux A; Marabelle A; Valsesia-Wittmann S Cancer Lett; 2015 Feb; 357(1):412-418. PubMed ID: 25475555 [TBL] [Abstract][Full Text] [Related]
39. SKP2 is a direct transcriptional target of MYCN and a potential therapeutic target in neuroblastoma. Evans L; Chen L; Milazzo G; Gherardi S; Perini G; Willmore E; Newell DR; Tweddle DA Cancer Lett; 2015 Jul; 363(1):37-45. PubMed ID: 25843293 [TBL] [Abstract][Full Text] [Related]
40. Vasoactive intestinal peptide decreases MYCN expression and synergizes with retinoic acid in a human MYCN-amplified neuroblastoma cell line. Chevrier L; Meunier AC; Cochaud S; Muller JM; Chadéneau C Int J Oncol; 2008 Nov; 33(5):1081-9. PubMed ID: 18949372 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]