BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 16913727)

  • 1. Synthesis and cytotoxic evaluation of combretafurans, potential scaffolds for dual-action antitumoral agents.
    Pirali T; Busacca S; Beltrami L; Imovilli D; Pagliai F; Miglio G; Massarotti A; Verotta L; Tron GC; Sorba G; Genazzani AA
    J Med Chem; 2006 Aug; 49(17):5372-6. PubMed ID: 16913727
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and biological activity of fluorinated combretastatin analogues.
    Alloatti D; Giannini G; Cabri W; Lustrati I; Marzi M; Ciacci A; Gallo G; Tinti MO; Marcellini M; Riccioni T; Guglielmi MB; Carminati P; Pisano C
    J Med Chem; 2008 May; 51(9):2708-21. PubMed ID: 18396857
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Combretastatin dinitrogen-substituted stilbene analogues as tubulin-binding and vascular-disrupting agents.
    Siles R; Ackley JF; Hadimani MB; Hall JJ; Mugabe BE; Guddneppanavar R; Monk KA; Chapuis JC; Pettit GR; Chaplin DJ; Edvardsen K; Trawick ML; Garner CM; Pinney KG
    J Nat Prod; 2008 Mar; 71(3):313-20. PubMed ID: 18303849
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and biological activity of mustard derivatives of combretastatins.
    Coggiola B; Pagliai F; Allegrone G; Genazzani AA; Tron GC
    Bioorg Med Chem Lett; 2005 Aug; 15(15):3551-4. PubMed ID: 15963722
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and evaluation of double bond substituted combretastatins.
    Hadfield JA; Gaukroger K; Hirst N; Weston AP; Lawrence NJ; McGown AT
    Eur J Med Chem; 2005 Jun; 40(6):529-41. PubMed ID: 15922837
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Naphthalene combretastatin analogues: synthesis, cytotoxicity and antitubulin activity.
    Medarde M; Maya AB; Pérez-Melero C
    J Enzyme Inhib Med Chem; 2004 Dec; 19(6):521-40. PubMed ID: 15662956
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regioselective Suzuki coupling of dihaloheteroaromatic compounds as a rapid strategy to synthesize potent rigid combretastatin analogues.
    Theeramunkong S; Caldarelli A; Massarotti A; Aprile S; Caprioglio D; Zaninetti R; Teruggi A; Pirali T; Grosa G; Tron GC; Genazzani AA
    J Med Chem; 2011 Jul; 54(14):4977-86. PubMed ID: 21696175
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lead identification of conformationally restricted β-lactam type combretastatin analogues: synthesis, antiproliferative activity and tubulin targeting effects.
    Carr M; Greene LM; Knox AJ; Lloyd DG; Zisterer DM; Meegan MJ
    Eur J Med Chem; 2010 Dec; 45(12):5752-66. PubMed ID: 20933304
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, antiproliferative, anti-tubulin activity, and docking study of new 1,2,4-triazoles as potential combretastatin analogues.
    Mustafa M; Abdelhamid D; Abdelhafez EMN; Ibrahim MAA; Gamal-Eldeen AM; Aly OM
    Eur J Med Chem; 2017 Dec; 141():293-305. PubMed ID: 29031074
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural requirements for the interaction of combretastatins with tubulin: how important is the trimethoxy unit?
    Gaukroger K; Hadfield JA; Lawrence NJ; Nolan S; McGown AT
    Org Biomol Chem; 2003 Sep; 1(17):3033-7. PubMed ID: 14518125
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, and biological evaluation of combretastatin nitrogen-containing derivatives as inhibitors of tubulin assembly and vascular disrupting agents.
    Monk KA; Siles R; Hadimani MB; Mugabe BE; Ackley JF; Studerus SW; Edvardsen K; Trawick ML; Garner CM; Rhodes MR; Pettit GR; Pinney KG
    Bioorg Med Chem; 2006 May; 14(9):3231-44. PubMed ID: 16442292
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis, biochemical, and biological evaluation of nitrogen-containing trifluoro structural modifications of combretastatin A-4.
    Hall JJ; Sriram M; Strecker TE; Tidmore JK; Jelinek CJ; Kumar GD; Hadimani MB; Pettit GR; Chaplin DJ; Trawick ML; Pinney KG
    Bioorg Med Chem Lett; 2008 Sep; 18(18):5146-9. PubMed ID: 18710804
    [TBL] [Abstract][Full Text] [Related]  

  • 13. New naphthylcombretastatins. Modifications on the ethylene bridge.
    Sánchez Maya AB; Pérez-Melero C; Salvador N; Peláez R; Caballero E; Medarde M
    Bioorg Med Chem; 2005 Mar; 13(6):2097-107. PubMed ID: 15727863
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 1,5-Disubstituted 1,2,3-triazoles as cis-restricted analogues of combretastatin A-4: Synthesis, molecular modeling and evaluation as cytotoxic agents and inhibitors of tubulin.
    Odlo K; Hentzen J; dit Chabert JF; Ducki S; Gani OA; Sylte I; Skrede M; Flørenes VA; Hansen TV
    Bioorg Med Chem; 2008 May; 16(9):4829-38. PubMed ID: 18396050
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis and biological evaluation of dihydronaphthalene and benzosuberene analogs of the combretastatins as inhibitors of tubulin polymerization in cancer chemotherapy.
    Sriram M; Hall JJ; Grohmann NC; Strecker TE; Wootton T; Franken A; Trawick ML; Pinney KG
    Bioorg Med Chem; 2008 Sep; 16(17):8161-71. PubMed ID: 18722127
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and biological evaluation of cis-restricted triazole/tetrazole mimics of combretastatin-benzothiazole hybrids as tubulin polymerization inhibitors and apoptosis inducers.
    Subba Rao AV; Swapna K; Shaik SP; Lakshma Nayak V; Srinivasa Reddy T; Sunkari S; Shaik TB; Bagul C; Kamal A
    Bioorg Med Chem; 2017 Feb; 25(3):977-999. PubMed ID: 28034647
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biological activity of naphthalene analogues of phenstatins: naphthylphenstatins.
    Alvarez C; Alvarez R; Corchete P; Pérez-Melero C; Peláez R; Medarde M
    Bioorg Med Chem Lett; 2007 Jun; 17(12):3417-20. PubMed ID: 17434303
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and biological evaluation of 3-(trimethoxyphenyl)-2(3H)-thiazole thiones as combretastatin analogs.
    Banimustafa M; Kheirollahi A; Safavi M; Kabudanian Ardestani S; Aryapour H; Foroumadi A; Emami S
    Eur J Med Chem; 2013; 70():692-702. PubMed ID: 24219991
    [