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4. The biochemical basis of gangliosidoses. Sandhoff K; Conzelmann E Neuropediatrics; 1984 Sep; 15 Suppl():85-92. PubMed ID: 6242704 [No Abstract] [Full Text] [Related]
5. Natural history and inherited disorders of a lysosomal enzyme, beta-hexosaminidase. Neufeld EF J Biol Chem; 1989 Jul; 264(19):10927-30. PubMed ID: 2525553 [No Abstract] [Full Text] [Related]
6. [Recent advances in molecular genetics of GM2 gangliosidosis]. Wakamatsu N Nihon Rinsho; 1995 Dec; 53(12):2988-93. PubMed ID: 8577047 [TBL] [Abstract][Full Text] [Related]
7. Dramatically different phenotypes in mouse models of human Tay-Sachs and Sandhoff diseases. Phaneuf D; Wakamatsu N; Huang JQ; Borowski A; Peterson AC; Fortunato SR; Ritter G; Igdoura SA; Morales CR; Benoit G; Akerman BR; Leclerc D; Hanai N; Marth JD; Trasler JM; Gravel RA Hum Mol Genet; 1996 Jan; 5(1):1-14. PubMed ID: 8789434 [TBL] [Abstract][Full Text] [Related]
8. Promoters for the human beta-hexosaminidase genes, HEXA and HEXB. Norflus F; Yamanaka S; Proia RL DNA Cell Biol; 1996 Feb; 15(2):89-97. PubMed ID: 8634145 [TBL] [Abstract][Full Text] [Related]
9. The biochemistry of HEXA and HEXB gene mutations causing GM2 gangliosidosis. Mahuran DJ Biochim Biophys Acta; 1991 Feb; 1096(2):87-94. PubMed ID: 1825792 [No Abstract] [Full Text] [Related]
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11. Production of recombinant beta-hexosaminidase A, a potential enzyme for replacement therapy for Tay-Sachs and Sandhoff diseases, in the methylotrophic yeast Ogataea minuta. Akeboshi H; Chiba Y; Kasahara Y; Takashiba M; Takaoka Y; Ohsawa M; Tajima Y; Kawashima I; Tsuji D; Itoh K; Sakuraba H; Jigami Y Appl Environ Microbiol; 2007 Aug; 73(15):4805-12. PubMed ID: 17557860 [TBL] [Abstract][Full Text] [Related]
12. Apoptotic cell death in mouse models of GM2 gangliosidosis and observations on human Tay-Sachs and Sandhoff diseases. Huang JQ; Trasler JM; Igdoura S; Michaud J; Hanal N; Gravel RA Hum Mol Genet; 1997 Oct; 6(11):1879-85. PubMed ID: 9302266 [TBL] [Abstract][Full Text] [Related]
13. Restoration of hexosaminidase A activity in human Tay-Sachs fibroblasts via adenoviral vector-mediated gene transfer. Akli S; Guidotti JE; Vigne E; Perricaudet M; Sandhoff K; Kahn A; Poenaru L Gene Ther; 1996 Sep; 3(9):769-74. PubMed ID: 8875224 [TBL] [Abstract][Full Text] [Related]
14. Crystal structure of human beta-hexosaminidase B: understanding the molecular basis of Sandhoff and Tay-Sachs disease. Mark BL; Mahuran DJ; Cherney MM; Zhao D; Knapp S; James MN J Mol Biol; 2003 Apr; 327(5):1093-109. PubMed ID: 12662933 [TBL] [Abstract][Full Text] [Related]
15. Biochemical consequences of mutations causing the GM2 gangliosidoses. Mahuran DJ Biochim Biophys Acta; 1999 Oct; 1455(2-3):105-38. PubMed ID: 10571007 [TBL] [Abstract][Full Text] [Related]
16. Neuronal lysosomal enzyme replacement using fragment C of tetanus toxin. Dobrenis K; Joseph A; Rattazzi MC Proc Natl Acad Sci U S A; 1992 Mar; 89(6):2297-301. PubMed ID: 1532255 [TBL] [Abstract][Full Text] [Related]
17. The beta-hexosaminidase deficiency disorders: development of a clinical paradigm in the mouse. Tifft CJ; Proia RL Ann Med; 1997 Dec; 29(6):557-61. PubMed ID: 9562524 [TBL] [Abstract][Full Text] [Related]
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