BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 16918475)

  • 1. Structure and mechanism of arylamine N-acetyltransferases.
    Westwood IM; Kawamura A; Fullam E; Russell AJ; Davies SG; Sim E
    Curr Top Med Chem; 2006; 6(15):1641-54. PubMed ID: 16918475
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Arylamine N-acetyltransferases: a pharmacogenomic approach to drug metabolism and endogenous function.
    Sim E; Pinter K; Mushtaq A; Upton A; Sandy J; Bhakta S; Noble M
    Biochem Soc Trans; 2003 Jun; 31(Pt 3):615-9. PubMed ID: 12773167
    [TBL] [Abstract][Full Text] [Related]  

  • 3. An approach to identifying novel substrates of bacterial arylamine N-acetyltransferases.
    Brooke EW; Davies SG; Mulvaney AW; Pompeo F; Sim E; Vickers RJ
    Bioorg Med Chem; 2003 Apr; 11(7):1227-34. PubMed ID: 12628650
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The pharmacogenetics of NAT: structural aspects.
    Pompeo F; Brooke E; Kawamura A; Mushtaq A; Sim E
    Pharmacogenomics; 2002 Jan; 3(1):19-30. PubMed ID: 11966400
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Investigation of the catalytic triad of arylamine N-acetyltransferases: essential residues required for acetyl transfer to arylamines.
    Sandy J; Mushtaq A; Holton SJ; Schartau P; Noble ME; Sim E
    Biochem J; 2005 Aug; 390(Pt 1):115-23. PubMed ID: 15869465
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal structure of arylamine N-acetyltransferases: insights into the mechanisms of action and substrate selectivity.
    Kubiak X; Dairou J; Dupret JM; Rodrigues-Lima F
    Expert Opin Drug Metab Toxicol; 2013 Mar; 9(3):349-62. PubMed ID: 23289949
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Arylamine N-acetyltransferases: from structure to function.
    Sim E; Walters K; Boukouvala S
    Drug Metab Rev; 2008; 40(3):479-510. PubMed ID: 18642144
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural and biochemical characterization of an active arylamine N-acetyltransferase possessing a non-canonical Cys-His-Glu catalytic triad.
    Kubiak X; Li de la Sierra-Gallay I; Chaffotte AF; Pluvinage B; Weber P; Haouz A; Dupret JM; Rodrigues-Lima F
    J Biol Chem; 2013 Aug; 288(31):22493-505. PubMed ID: 23770703
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Arylamine N-acetyltransferases: structural and functional implications of polymorphisms.
    Sim E; Lack N; Wang CJ; Long H; Westwood I; Fullam E; Kawamura A
    Toxicology; 2008 Dec; 254(3):170-83. PubMed ID: 18852012
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Divergence of cofactor recognition across evolution: coenzyme A binding in a prokaryotic arylamine N-acetyltransferase.
    Fullam E; Westwood IM; Anderton MC; Lowe ED; Sim E; Noble ME
    J Mol Biol; 2008 Jan; 375(1):178-91. PubMed ID: 18005984
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Arylamine N-acetyltransferases: a structural perspective.
    Zhou X; Ma Z; Dong D; Wu B
    Br J Pharmacol; 2013 Jun; 169(4):748-60. PubMed ID: 23517104
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Eubacterial arylamine N-acetyltransferases - identification and comparison of 18 members of the protein family with conserved active site cysteine, histidine and aspartate residues.
    Payton M; Mushtaq A; Yu TW; Wu LJ; Sinclair J; Sim E
    Microbiology (Reading); 2001 May; 147(Pt 5):1137-1147. PubMed ID: 11320117
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The COOH terminus of arylamine N-acetyltransferase from Salmonella typhimurium controls enzymic activity.
    Mushtaq A; Payton M; Sim E
    J Biol Chem; 2002 Apr; 277(14):12175-81. PubMed ID: 11799105
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Arylamine N-acetyltransferases: from drug metabolism and pharmacogenetics to drug discovery.
    Sim E; Abuhammad A; Ryan A
    Br J Pharmacol; 2014 Jun; 171(11):2705-25. PubMed ID: 24467436
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The structure of arylamine N-acetyltransferase from Mycobacterium smegmatis--an enzyme which inactivates the anti-tubercular drug, isoniazid.
    Sandy J; Mushtaq A; Kawamura A; Sinclair J; Sim E; Noble M
    J Mol Biol; 2002 May; 318(4):1071-83. PubMed ID: 12054803
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Arylamine N-acetyltransferases--from drug metabolism and pharmacogenetics to identification of novel targets for pharmacological intervention.
    Sim E; Fakis G; Laurieri N; Boukouvala S
    Adv Pharmacol; 2012; 63():169-205. PubMed ID: 22776642
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Kinetic characterisation of arylamine N-acetyltransferase from Pseudomonas aeruginosa.
    Westwood IM; Sim E
    BMC Biochem; 2007 Mar; 8():3. PubMed ID: 17374145
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural and functional characterization of an arylamine N-acetyltransferase from the pathogen Mycobacterium abscessus: differences from other mycobacterial isoforms and implications for selective inhibition.
    Cocaign A; Kubiak X; Xu X; Garnier G; Li de la Sierra-Gallay I; Chi-Bui L; Dairou J; Busi F; Abuhammad A; Haouz A; Dupret JM; Herrmann JL; Rodrigues-Lima F
    Acta Crystallogr D Biol Crystallogr; 2014 Nov; 70(Pt 11):3066-79. PubMed ID: 25372695
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Probing the mechanism of hamster arylamine N-acetyltransferase 2 acetylation by active site modification, site-directed mutagenesis, and pre-steady state and steady state kinetic studies.
    Wang H; Vath GM; Gleason KJ; Hanna PE; Wagner CR
    Biochemistry; 2004 Jun; 43(25):8234-46. PubMed ID: 15209520
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure of Mesorhizobium loti arylamine N-acetyltransferase 1.
    Holton SJ; Dairou J; Sandy J; Rodrigues-Lima F; Dupret JM; Noble ME; Sim E
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2005 Jan; 61(Pt 1):14-6. PubMed ID: 16508079
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.