These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

309 related articles for article (PubMed ID: 16919418)

  • 1. GAA repeat expansion mutation mouse models of Friedreich ataxia exhibit oxidative stress leading to progressive neuronal and cardiac pathology.
    Al-Mahdawi S; Pinto RM; Varshney D; Lawrence L; Lowrie MB; Hughes S; Webster Z; Blake J; Cooper JM; King R; Pook MA
    Genomics; 2006 Nov; 88(5):580-90. PubMed ID: 16919418
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel GAA-repeat-expansion-based mouse model of Friedreich's ataxia.
    Anjomani Virmouni S; Ezzatizadeh V; Sandi C; Sandi M; Al-Mahdawi S; Chutake Y; Pook MA
    Dis Model Mech; 2015 Mar; 8(3):225-35. PubMed ID: 25681319
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cellular, molecular and functional characterisation of YAC transgenic mouse models of Friedreich ataxia.
    Anjomani Virmouni S; Sandi C; Al-Mahdawi S; Pook MA
    PLoS One; 2014; 9(9):e107416. PubMed ID: 25198290
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Generation and characterisation of Friedreich ataxia YG8R mouse fibroblast and neural stem cell models.
    Sandi C; Sandi M; Jassal H; Ezzatizadeh V; Anjomani-Virmouni S; Al-Mahdawi S; Pook MA
    PLoS One; 2014; 9(2):e89488. PubMed ID: 24586819
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Friedreich ataxia GAA repeat expansion mutation induces comparable epigenetic changes in human and transgenic mouse brain and heart tissues.
    Al-Mahdawi S; Pinto RM; Ismail O; Varshney D; Lymperi S; Sandi C; Trabzuni D; Pook M
    Hum Mol Genet; 2008 Mar; 17(5):735-46. PubMed ID: 18045775
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A GAA repeat expansion reporter model of Friedreich's ataxia recapitulates the genomic context and allows rapid screening of therapeutic compounds.
    Lufino MM; Silva AM; Németh AH; Alegre-Abarrategui J; Russell AJ; Wade-Martins R
    Hum Mol Genet; 2013 Dec; 22(25):5173-87. PubMed ID: 23943791
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MutLα heterodimers modify the molecular phenotype of Friedreich ataxia.
    Ezzatizadeh V; Sandi C; Sandi M; Anjomani-Virmouni S; Al-Mahdawi S; Pook MA
    PLoS One; 2014; 9(6):e100523. PubMed ID: 24971578
    [TBL] [Abstract][Full Text] [Related]  

  • 8. GAA repeat instability in Friedreich ataxia YAC transgenic mice.
    Al-Mahdawi S; Pinto RM; Ruddle P; Carroll C; Webster Z; Pook M
    Genomics; 2004 Aug; 84(2):301-10. PubMed ID: 15233994
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transcriptional profiling of isogenic Friedreich ataxia neurons and effect of an HDAC inhibitor on disease signatures.
    Lai JI; Nachun D; Petrosyan L; Throesch B; Campau E; Gao F; Baldwin KK; Coppola G; Gottesfeld JM; Soragni E
    J Biol Chem; 2019 Feb; 294(6):1846-1859. PubMed ID: 30552117
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The GAA triplet-repeat is unstable in the context of the human FXN locus and displays age-dependent expansions in cerebellum and DRG in a transgenic mouse model.
    Clark RM; De Biase I; Malykhina AP; Al-Mahdawi S; Pook M; Bidichandani SI
    Hum Genet; 2007 Jan; 120(5):633-40. PubMed ID: 17024371
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mitochondrial damage and senescence phenotype of cells derived from a novel frataxin G127V point mutation mouse model of Friedreich's ataxia.
    Fil D; Chacko BK; Conley R; Ouyang X; Zhang J; Darley-Usmar VM; Zuberi AR; Lutz CM; Napierala M; Napierala JS
    Dis Model Mech; 2020 Jul; 13(7):. PubMed ID: 32586831
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Prolonged treatment with pimelic o-aminobenzamide HDAC inhibitors ameliorates the disease phenotype of a Friedreich ataxia mouse model.
    Sandi C; Pinto RM; Al-Mahdawi S; Ezzatizadeh V; Barnes G; Jones S; Rusche JR; Gottesfeld JM; Pook MA
    Neurobiol Dis; 2011 Jun; 42(3):496-505. PubMed ID: 21397024
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Generation and characterization of iPSC lines from Friedreich's ataxia patient (FRDA) with GAA.TTC repeat expansion in the Frataxin (FXN) gene's first intron (IGIBi016-A) and a non-FRDA healthy control individual (IGIBi017-A).
    Ahmad I; Kamai A; Zahra S; Kapoor H; Kumar Srivastava A; Faruq M
    Stem Cell Res; 2024 Jun; 77():103382. PubMed ID: 38484450
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Beyond loss of frataxin: the complex molecular pathology of Friedreich ataxia.
    Evans-Galea MV; Lockhart PJ; Galea CA; Hannan AJ; Delatycki MB
    Discov Med; 2014 Jan; 17(91):25-35. PubMed ID: 24411698
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Exenatide induces frataxin expression and improves mitochondrial function in Friedreich ataxia.
    Igoillo-Esteve M; Oliveira AF; Cosentino C; Fantuzzi F; Demarez C; Toivonen S; Hu A; Chintawar S; Lopes M; Pachera N; Cai Y; Abdulkarim B; Rai M; Marselli L; Marchetti P; Tariq M; Jonas JC; Boscolo M; Pandolfo M; Eizirik DL; Cnop M
    JCI Insight; 2020 Jan; 5(2):. PubMed ID: 31877117
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Missense mutations linked to friedreich ataxia have different but synergistic effects on mitochondrial frataxin isoforms.
    Li H; Gakh O; Smith DY; Ranatunga WK; Isaya G
    J Biol Chem; 2013 Feb; 288(6):4116-27. PubMed ID: 23269675
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA methylation in Friedreich ataxia silences expression of frataxin isoform E.
    Rodden LN; Gilliam KM; Lam C; Rojsajjakul T; Mesaros C; Dionisi C; Pook M; Pandolfo M; Lynch DR; Blair IA; Bidichandani SI
    Sci Rep; 2022 Mar; 12(1):5031. PubMed ID: 35322126
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Frataxin gene point mutations in Italian Friedreich ataxia patients.
    Gellera C; Castellotti B; Mariotti C; Mineri R; Seveso V; Didonato S; Taroni F
    Neurogenetics; 2007 Nov; 8(4):289-99. PubMed ID: 17703324
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Neurobehavioral deficits of mice expressing a low level of G127V mutant frataxin.
    Fil D; Conley RL; Zuberi AR; Lutz CM; Gemelli T; Napierala M; Napierala JS
    Neurobiol Dis; 2023 Feb; 177():105996. PubMed ID: 36638893
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Multicellular models of Friedreich ataxia.
    Puccio H
    J Neurol; 2009 Mar; 256 Suppl 1():18-24. PubMed ID: 19283346
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.