271 related articles for article (PubMed ID: 16922658)
1. From physicochemistry to absorption and distribution: predictive mechanistic modelling and computational tools.
Willmann S; Lippert J; Schmitt W
Expert Opin Drug Metab Toxicol; 2005 Jun; 1(1):159-68. PubMed ID: 16922658
[TBL] [Abstract][Full Text] [Related]
2. High-throughput pKa screening and prediction amenable for ADME profiling.
Wan H; Ulander J
Expert Opin Drug Metab Toxicol; 2006 Feb; 2(1):139-55. PubMed ID: 16863474
[TBL] [Abstract][Full Text] [Related]
3. From in vivo to in vitro/in silico ADME: progress and challenges.
Van de Waterbeemd H
Expert Opin Drug Metab Toxicol; 2005 Jun; 1(1):1-4. PubMed ID: 16922647
[TBL] [Abstract][Full Text] [Related]
4. Development and application of physiologically based pharmacokinetic-modeling tools to support drug discovery.
Lüpfert C; Reichel A
Chem Biodivers; 2005 Nov; 2(11):1462-86. PubMed ID: 17191947
[TBL] [Abstract][Full Text] [Related]
5. Computational prediction of human drug metabolism.
Ekins S; Andreyev S; Ryabov A; Kirillov E; Rakhmatulin EA; Bugrim A; Nikolskaya T
Expert Opin Drug Metab Toxicol; 2005 Aug; 1(2):303-24. PubMed ID: 16922645
[TBL] [Abstract][Full Text] [Related]
6. ADME evaluation. 2. A computer model for the prediction of intestinal absorption in humans.
Klopman G; Stefan LR; Saiakhov RD
Eur J Pharm Sci; 2002 Dec; 17(4-5):253-63. PubMed ID: 12453615
[TBL] [Abstract][Full Text] [Related]
7. Metabolic stability for drug discovery and development: pharmacokinetic and biochemical challenges.
Masimirembwa CM; Bredberg U; Andersson TB
Clin Pharmacokinet; 2003; 42(6):515-28. PubMed ID: 12793837
[TBL] [Abstract][Full Text] [Related]
8. In silico predictions of gastrointestinal drug absorption in pharmaceutical product development: application of the mechanistic absorption model GI-Sim.
Sjögren E; Westergren J; Grant I; Hanisch G; Lindfors L; Lennernäs H; Abrahamsson B; Tannergren C
Eur J Pharm Sci; 2013 Jul; 49(4):679-98. PubMed ID: 23727464
[TBL] [Abstract][Full Text] [Related]
9. In silico prediction of ADME and pharmacokinetics. Report of an expert meeting organised by COST B15.
Boobis A; Gundert-Remy U; Kremers P; Macheras P; Pelkonen O
Eur J Pharm Sci; 2002 Dec; 17(4-5):183-93. PubMed ID: 12453607
[TBL] [Abstract][Full Text] [Related]
10. Classification structure-activity relations (C-SAR) in prediction of human intestinal absorption.
Zmuidinavicius D; Didziapetris R; Japertas P; Avdeef A; Petrauskas A
J Pharm Sci; 2003 Mar; 92(3):621-33. PubMed ID: 12587124
[TBL] [Abstract][Full Text] [Related]
11. Pharmacokinetic properties and in silico ADME modeling in drug discovery.
Honório KM; Moda TL; Andricopulo AD
Med Chem; 2013 Mar; 9(2):163-76. PubMed ID: 23016542
[TBL] [Abstract][Full Text] [Related]
12. Troubleshooting computational methods in drug discovery.
Kortagere S; Ekins S
J Pharmacol Toxicol Methods; 2010; 61(2):67-75. PubMed ID: 20176118
[TBL] [Abstract][Full Text] [Related]
13. In Silico Modeling of Gastrointestinal Drug Absorption: Predictive Performance of Three Physiologically Based Absorption Models.
Sjögren E; Thörn H; Tannergren C
Mol Pharm; 2016 Jun; 13(6):1763-78. PubMed ID: 26926043
[TBL] [Abstract][Full Text] [Related]
14. Structure-based virtual screening: an overview.
Lyne PD
Drug Discov Today; 2002 Oct; 7(20):1047-55. PubMed ID: 12546894
[TBL] [Abstract][Full Text] [Related]
15. Two-dimensional (2D) in silico models for absorption, distribution, metabolism, excretion and toxicity (ADME/T) in drug discovery.
Khakar PS
Curr Top Med Chem; 2010; 10(1):116-26. PubMed ID: 19929825
[TBL] [Abstract][Full Text] [Related]
16. The influence of DMPK as an integrated partner in modern drug discovery.
Riley RJ; Martin IJ; Cooper AE
Curr Drug Metab; 2002 Oct; 3(5):527-50. PubMed ID: 12369896
[TBL] [Abstract][Full Text] [Related]
17. Computational chemistry as an integral component of lead generation.
Roche O; Guba W
Mini Rev Med Chem; 2005 Jul; 5(7):677-83. PubMed ID: 16026314
[TBL] [Abstract][Full Text] [Related]
18. Prediction of intestinal absorption: comparative assessment of GASTROPLUS and IDEA.
Parrott N; Lavé T
Eur J Pharm Sci; 2002 Oct; 17(1-2):51-61. PubMed ID: 12356420
[TBL] [Abstract][Full Text] [Related]
19. Theoretical predictions of drug absorption in drug discovery and development.
Stenberg P; Bergström CA; Luthman K; Artursson P
Clin Pharmacokinet; 2002; 41(11):877-99. PubMed ID: 12190333
[TBL] [Abstract][Full Text] [Related]
20. High-throughput and in silico techniques in drug metabolism and pharmacokinetics.
van de Waterbeemd H
Curr Opin Drug Discov Devel; 2002 Jan; 5(1):33-43. PubMed ID: 11865671
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]