These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

521 related articles for article (PubMed ID: 16928813)

  • 1. Differential roles of checkpoint kinase 1, checkpoint kinase 2, and mitogen-activated protein kinase-activated protein kinase 2 in mediating DNA damage-induced cell cycle arrest: implications for cancer therapy.
    Xiao Z; Xue J; Sowin TJ; Zhang H
    Mol Cancer Ther; 2006 Aug; 5(8):1935-43. PubMed ID: 16928813
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel mechanism of checkpoint abrogation conferred by Chk1 downregulation.
    Xiao Z; Xue J; Sowin TJ; Rosenberg SH; Zhang H
    Oncogene; 2005 Feb; 24(8):1403-11. PubMed ID: 15608676
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Selective Chk1 inhibitors differentially sensitize p53-deficient cancer cells to cancer therapeutics.
    Chen Z; Xiao Z; Gu WZ; Xue J; Bui MH; Kovar P; Li G; Wang G; Tao ZF; Tong Y; Lin NH; Sham HL; Wang JY; Sowin TJ; Rosenberg SH; Zhang H
    Int J Cancer; 2006 Dec; 119(12):2784-94. PubMed ID: 17019715
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DNA damage activates a spatially distinct late cytoplasmic cell-cycle checkpoint network controlled by MK2-mediated RNA stabilization.
    Reinhardt HC; Hasskamp P; Schmedding I; Morandell S; van Vugt MA; Wang X; Linding R; Ong SE; Weaver D; Carr SA; Yaffe MB
    Mol Cell; 2010 Oct; 40(1):34-49. PubMed ID: 20932473
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dual regulation of Cdc25A by Chk1 and p53-ATF3 in DNA replication checkpoint control.
    Demidova AR; Aau MY; Zhuang L; Yu Q
    J Biol Chem; 2009 Feb; 284(7):4132-9. PubMed ID: 19060337
    [TBL] [Abstract][Full Text] [Related]  

  • 6. p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage.
    Reinhardt HC; Aslanian AS; Lees JA; Yaffe MB
    Cancer Cell; 2007 Feb; 11(2):175-89. PubMed ID: 17292828
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA damage-induced S phase arrest in human breast cancer depends on Chk1, but G2 arrest can occur independently of Chk1, Chk2 or MAPKAPK2.
    Zhang WH; Poh A; Fanous AA; Eastman A
    Cell Cycle; 2008 Jun; 7(11):1668-77. PubMed ID: 18469532
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mitotic DNA damage response: Polo-like kinase-1 is dephosphorylated through ATM-Chk1 pathway.
    Lee HJ; Hwang HI; Jang YJ
    Cell Cycle; 2010 Jun; 9(12):2389-98. PubMed ID: 20581453
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Knockdown of Chk1 sensitizes human colon carcinoma HCT116 cells in a p53-dependent manner to lidamycin through abrogation of a G2/M checkpoint and induction of apoptosis.
    Pan Y; Ren KH; He HW; Shao RG
    Cancer Biol Ther; 2009 Aug; 8(16):1559-66. PubMed ID: 19502782
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Chk1, but not Chk2, is involved in the cellular response to DNA damaging agents: differential activity in cells expressing or not p53.
    Carrassa L; Broggini M; Erba E; Damia G
    Cell Cycle; 2004 Sep; 3(9):1177-81. PubMed ID: 15326376
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chk1 mediates S and G2 arrests through Cdc25A degradation in response to DNA-damaging agents.
    Xiao Z; Chen Z; Gunasekera AH; Sowin TJ; Rosenberg SH; Fesik S; Zhang H
    J Biol Chem; 2003 Jun; 278(24):21767-73. PubMed ID: 12676925
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chk1 and Chk2 are differentially involved in homologous recombination repair and cell cycle arrest in response to DNA double-strand breaks induced by camptothecins.
    Huang M; Miao ZH; Zhu H; Cai YJ; Lu W; Ding J
    Mol Cancer Ther; 2008 Jun; 7(6):1440-9. PubMed ID: 18566216
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CHK1 and CHK2 are differentially involved in mismatch repair-mediated 6-thioguanine-induced cell cycle checkpoint responses.
    Yan T; Desai AB; Jacobberger JW; Sramkoski RM; Loh T; Kinsella TJ
    Mol Cancer Ther; 2004 Sep; 3(9):1147-57. PubMed ID: 15367709
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional.
    Lossaint G; Besnard E; Fisher D; Piette J; Dulić V
    Oncogene; 2011 Oct; 30(41):4261-74. PubMed ID: 21532626
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2.
    Reinhardt HC; Yaffe MB
    Curr Opin Cell Biol; 2009 Apr; 21(2):245-55. PubMed ID: 19230643
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential roles for checkpoint kinases in DNA damage-dependent degradation of the Cdc25A protein phosphatase.
    Jin J; Ang XL; Ye X; Livingstone M; Harper JW
    J Biol Chem; 2008 Jul; 283(28):19322-8. PubMed ID: 18480045
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential impact of diverse anticancer chemotherapeutics on the Cdc25A-degradation checkpoint pathway.
    Agner J; Falck J; Lukas J; Bartek J
    Exp Cell Res; 2005 Jan; 302(2):162-9. PubMed ID: 15561098
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Chk1 is essential for tumor cell viability following activation of the replication checkpoint.
    Cho SH; Toouli CD; Fujii GH; Crain C; Parry D
    Cell Cycle; 2005 Jan; 4(1):131-9. PubMed ID: 15539958
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel indication for cancer therapy: Chk1 inhibition sensitizes tumor cells to antimitotics.
    Xiao Z; Xue J; Semizarov D; Sowin TJ; Rosenberg SH; Zhang H
    Int J Cancer; 2005 Jul; 115(4):528-38. PubMed ID: 15688426
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Co-abrogation of Chk1 and Chk2 by potent oncolytic adenovirus potentiates the antitumor efficacy of cisplatin or irradiation.
    Ye F; Yang Z; Liu Y; Gong D; Ji T; Wang J; Xi B; Zhou J; Ma D; Gao Q
    Cancer Gene Ther; 2014 May; 21(5):209-17. PubMed ID: 24853623
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.