BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

597 related articles for article (PubMed ID: 16938516)

  • 1. The value of MDM2 and CDK4 amplification levels using real-time polymerase chain reaction for the differential diagnosis of liposarcomas and their histologic mimickers.
    Shimada S; Ishizawa T; Ishizawa K; Matsumura T; Hasegawa T; Hirose T
    Hum Pathol; 2006 Sep; 37(9):1123-9. PubMed ID: 16938516
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Detection of MDM2-CDK4 amplification by fluorescence in situ hybridization in 200 paraffin-embedded tumor samples: utility in diagnosing adipocytic lesions and comparison with immunohistochemistry and real-time PCR.
    Sirvent N; Coindre JM; Maire G; Hostein I; Keslair F; Guillou L; Ranchere-Vince D; Terrier P; Pedeutour F
    Am J Surg Pathol; 2007 Oct; 31(10):1476-89. PubMed ID: 17895748
    [TBL] [Abstract][Full Text] [Related]  

  • 3. High level of CDK4 amplification is a poor prognostic factor in well-differentiated and dedifferentiated liposarcoma.
    Lee SE; Kim YJ; Kwon MJ; Choi DI; Lee J; Cho J; Seo SW; Kim SJ; Shin YK; Choi YL
    Histol Histopathol; 2014 Jan; 29(1):127-38. PubMed ID: 23852861
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Diagnostic utility of p16, CDK4, and MDM2 as an immunohistochemical panel in distinguishing well-differentiated and dedifferentiated liposarcomas from other adipocytic tumors.
    Thway K; Flora R; Shah C; Olmos D; Fisher C
    Am J Surg Pathol; 2012 Mar; 36(3):462-9. PubMed ID: 22301498
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Utility of fluorescence in situ hybridization to detect MDM2 amplification in liposarcomas and their morphological mimics.
    Kimura H; Dobashi Y; Nojima T; Nakamura H; Yamamoto N; Tsuchiya H; Ikeda H; Sawada-Kitamura S; Oyama T; Ooi A
    Int J Clin Exp Pathol; 2013; 6(7):1306-16. PubMed ID: 23826411
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Detection of MDM2/CDK4 amplification in lipomatous soft tissue tumors from formalin-fixed, paraffin-embedded tissue: comparison of multiplex ligation-dependent probe amplification (MLPA) and fluorescence in situ hybridization (FISH).
    Creytens D; van Gorp J; Ferdinande L; Speel EJ; Libbrecht L
    Appl Immunohistochem Mol Morphol; 2015 Feb; 23(2):126-33. PubMed ID: 25679065
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Evaluation of MDM2 and CDK4 amplification by real-time PCR on paraffin wax-embedded material: a potential tool for the diagnosis of atypical lipomatous tumours/well-differentiated liposarcomas.
    Hostein I; Pelmus M; Aurias A; Pedeutour F; Mathoulin-Pélissier S; Coindre JM
    J Pathol; 2004 Jan; 202(1):95-102. PubMed ID: 14694526
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential diagnosis of atypical lipomatous tumor/well-differentiated liposarcoma and dedifferentiated liposarcoma: utility of p16 in combination with MDM2 and CDK4 immunohistochemistry.
    Kammerer-Jacquet SF; Thierry S; Cabillic F; Lannes M; Burtin F; Henno S; Dugay F; Bouzillé G; Rioux-Leclercq N; Belaud-Rotureau MA; Stock N
    Hum Pathol; 2017 Jan; 59():34-40. PubMed ID: 27597521
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Liposarcomatous differentiation in malignant phyllodes tumours is unassociated with MDM2 or CDK4 amplification.
    Lyle PL; Bridge JA; Simpson JF; Cates JM; Sanders ME
    Histopathology; 2016 Jun; 68(7):1040-5. PubMed ID: 26542423
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Amplification of FRS2 in atypical lipomatous tumour/well-differentiated liposarcoma and de-differentiated liposarcoma: a clinicopathological and genetic study of 146 cases.
    Jing W; Lan T; Chen H; Zhang Z; Chen M; Peng R; He X; Zhang H
    Histopathology; 2018 Jun; 72(7):1145-1155. PubMed ID: 29368794
    [TBL] [Abstract][Full Text] [Related]  

  • 11. p16 Expression in Fat Necrosis: A Potential Diagnostic Pitfall in the Evaluation of Differentiated Adipocytic Neoplasms.
    Ng W; Messiou C; Smith M; Thway K
    Int J Surg Pathol; 2015 Oct; 23(7):544-8. PubMed ID: 26173427
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma With Features Mimicking Spindle Cell Lipoma.
    Jebastin JAS; Perry KD; Chitale DA; Mott MP; Sanchez J; Fritchie KJ; Palanisamy N; Williamson SR
    Int J Surg Pathol; 2020 May; 28(3):336-340. PubMed ID: 31672072
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Overlapping features between dedifferentiated liposarcoma and undifferentiated high-grade pleomorphic sarcoma.
    Chung L; Lau SK; Jiang Z; Loera S; Bedel V; Ji J; Weiss LM; Chu PG
    Am J Surg Pathol; 2009 Nov; 33(11):1594-600. PubMed ID: 19574885
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MDM2 RNA In Situ Hybridization for the Diagnosis of Atypical Lipomatous Tumor: A Study Evaluating DNA, RNA, and Protein Expression.
    Kulkarni AS; Wojcik JB; Chougule A; Arora K; Chittampalli Y; Kurzawa P; Mullen JT; Chebib I; Nielsen GP; Rivera MN; Ting DT; Deshpande V
    Am J Surg Pathol; 2019 Apr; 43(4):446-454. PubMed ID: 30520819
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Clinical value of fluorescence
    Wang W; Li X; Liu P; Dong Y
    Beijing Da Xue Xue Bao Yi Xue Ban; 2023 Apr; 55(2):228-233. PubMed ID: 37042132
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expression of FRS2 in atypical lipomatous tumor/well-differentiated liposarcoma and dedifferentiated liposarcoma: an immunohistochemical analysis of 182 cases with genetic data.
    Jing W; Lan T; Qiu Y; Peng R; Lu Y; Chen H; Chen M; He X; Chen C; Zhang H
    Diagn Pathol; 2021 Oct; 16(1):96. PubMed ID: 34696768
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MDM2 and CDK4 Immunohistochemistry: Should It Be Used in Problematic Differentiated Lipomatous Tumors?: A New Perspective.
    Clay MR; Martinez AP; Weiss SW; Edgar MA
    Am J Surg Pathol; 2016 Dec; 40(12):1647-1652. PubMed ID: 27508976
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sensitivity of MDM2 amplification and unexpected multiple faint alphoid 12 (alpha 12 satellite sequences) signals in atypical lipomatous tumor.
    Kashima T; Halai D; Ye H; Hing SN; Delaney D; Pollock R; O'Donnell P; Tirabosco R; Flanagan AM
    Mod Pathol; 2012 Oct; 25(10):1384-96. PubMed ID: 22699518
    [TBL] [Abstract][Full Text] [Related]  

  • 19. HMGA2 is the partner of MDM2 in well-differentiated and dedifferentiated liposarcomas whereas CDK4 belongs to a distinct inconsistent amplicon.
    Italiano A; Bianchini L; Keslair F; Bonnafous S; Cardot-Leccia N; Coindre JM; Dumollard JM; Hofman P; Leroux A; Mainguené C; Peyrottes I; Ranchere-Vince D; Terrier P; Tran A; Gual P; Pedeutour F
    Int J Cancer; 2008 May; 122(10):2233-41. PubMed ID: 18214854
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inflammatory malignant fibrous histiocytomas and dedifferentiated liposarcomas: histological review, genomic profile, and MDM2 and CDK4 status favour a single entity.
    Coindre JM; Hostein I; Maire G; Derré J; Guillou L; Leroux A; Ghnassia JP; Collin F; Pedeutour F; Aurias A
    J Pathol; 2004 Jul; 203(3):822-30. PubMed ID: 15221942
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 30.