142 related articles for article (PubMed ID: 16942014)
1. Homobivalent quinazolinimines as novel nanomolar inhibitors of cholinesterases with dirigible selectivity toward butyrylcholinesterase.
Decker M
J Med Chem; 2006 Sep; 49(18):5411-3. PubMed ID: 16942014
[TBL] [Abstract][Full Text] [Related]
2. Probing the mid-gorge of cholinesterases with spacer-modified bivalent quinazolinimines leads to highly potent and selective butyrylcholinesterase inhibitors.
Chen X; Tikhonova IG; Decker M
Bioorg Med Chem; 2011 Feb; 19(3):1222-35. PubMed ID: 21232964
[TBL] [Abstract][Full Text] [Related]
3. Novel tricyclic quinazolinimines and related tetracyclic nitrogen bridgehead compounds as cholinesterase inhibitors with selectivity towards butyrylcholinesterase.
Decker M; Krauth F; Lehmann J
Bioorg Med Chem; 2006 Mar; 14(6):1966-77. PubMed ID: 16289855
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and pharmacological evaluation of huprine-tacrine heterodimers: subnanomolar dual binding site acetylcholinesterase inhibitors.
Camps P; Formosa X; Muñoz-Torrero D; Petrignet J; Badia A; Clos MV
J Med Chem; 2005 Mar; 48(6):1701-4. PubMed ID: 15771413
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis and pharmacological evaluation of hybrid molecules out of quinazolinimines and lipoic acid lead to highly potent and selective butyrylcholinesterase inhibitors with antioxidant properties.
Decker M; Kraus B; Heilmann J
Bioorg Med Chem; 2008 Apr; 16(8):4252-61. PubMed ID: 18343673
[TBL] [Abstract][Full Text] [Related]
6. Specific targeting of acetylcholinesterase and butyrylcholinesterase recognition sites. Rational design of novel, selective, and highly potent cholinesterase inhibitors.
Savini L; Gaeta A; Fattorusso C; Catalanotti B; Campiani G; Chiasserini L; Pellerano C; Novellino E; McKissic D; Saxena A
J Med Chem; 2003 Jan; 46(1):1-4. PubMed ID: 12502352
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis and evaluation of isaindigotone derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors.
Pan L; Tan JH; Hou JQ; Huang SL; Gu LQ; Huang ZS
Bioorg Med Chem Lett; 2008 Jul; 18(13):3790-3. PubMed ID: 18524585
[TBL] [Abstract][Full Text] [Related]
8. Novel heterobivalent tacrine derivatives as cholinesterase inhibitors with notable selectivity toward butyrylcholinesterase.
Elsinghorst PW; Tanarro CM; Gütschow M
J Med Chem; 2006 Dec; 49(25):7540-4. PubMed ID: 17149883
[TBL] [Abstract][Full Text] [Related]
9. New potent acetylcholinesterase inhibitors in the tetracyclic triterpene series.
Sauvaître T; Barlier M; Herlem D; Gresh N; Chiaroni A; Guenard D; Guillou C
J Med Chem; 2007 Nov; 50(22):5311-23. PubMed ID: 17902635
[TBL] [Abstract][Full Text] [Related]
10. Discovery of huperzine A-tacrine hybrids as potent inhibitors of human cholinesterases targeting their midgorge recognition sites.
Gemma S; Gabellieri E; Huleatt P; Fattorusso C; Borriello M; Catalanotti B; Butini S; De Angelis M; Novellino E; Nacci V; Belinskaya T; Saxena A; Campiani G
J Med Chem; 2006 Jun; 49(11):3421-5. PubMed ID: 16722663
[TBL] [Abstract][Full Text] [Related]
11. Conjugates of Tacrine and Its Cyclic Homologues with p-Toluenesulfonamide as Novel Acetylcholinesterase and Butyrylcholinesterase Inhibitors.
Makhaeva GF; Kovaleva NV; Lushchekina SV; Rudakova EV; Boltneva NP; Proshin AN; Lednev BV; Serkov IV; Bachurin SO
Dokl Biochem Biophys; 2018 Nov; 483(1):369-373. PubMed ID: 30607741
[TBL] [Abstract][Full Text] [Related]
12. Bivalent 5,8,9,13b-tetrahydro-6H-isoquino[1,2-a]isoquinolines and -isoquinolinium salts: novel heterocyclic templates for butyrylcholinesterase inhibitors.
Schulze M; Siol O; Decker M; Lehmann J
Bioorg Med Chem Lett; 2010 May; 20(9):2946-9. PubMed ID: 20350808
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and biological evaluation of novel tacrine derivatives and tacrine-coumarin hybrids as cholinesterase inhibitors.
Hamulakova S; Janovec L; Hrabinova M; Spilovska K; Korabecny J; Kristian P; Kuca K; Imrich J
J Med Chem; 2014 Aug; 57(16):7073-84. PubMed ID: 25089370
[TBL] [Abstract][Full Text] [Related]
14. Novel donepezil-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.
Camps P; Formosa X; Galdeano C; Gómez T; Muñoz-Torrero D; Scarpellini M; Viayna E; Badia A; Clos MV; Camins A; Pallàs M; Bartolini M; Mancini F; Andrisano V; Estelrich J; Lizondo M; Bidon-Chanal A; Luque FJ
J Med Chem; 2008 Jun; 51(12):3588-98. PubMed ID: 18517184
[TBL] [Abstract][Full Text] [Related]
15. Increasing Polarity in Tacrine and Huprine Derivatives: Potent Anticholinesterase Agents for the Treatment of Myasthenia Gravis.
Galdeano C; Coquelle N; Cieslikiewicz-Bouet M; Bartolini M; Pérez B; Clos MV; Silman I; Jean L; Colletier JP; Renard PY; Muñoz-Torrero D
Molecules; 2018 Mar; 23(3):. PubMed ID: 29534488
[TBL] [Abstract][Full Text] [Related]
16. Synthesis, kinetic studies and molecular modeling of novel tacrine dimers as cholinesterase inhibitors.
de Aquino RA; Modolo LV; Alves RB; de Fátima Â
Org Biomol Chem; 2013 Dec; 11(48):8395-409. PubMed ID: 24186541
[TBL] [Abstract][Full Text] [Related]
17. Synthesis of tacrine analogues and their structure-activity relationships.
Proctor GR; Harvey AL
Curr Med Chem; 2000 Mar; 7(3):295-302. PubMed ID: 10637366
[TBL] [Abstract][Full Text] [Related]
18. New huprine derivatives functionalized at position 9 as highly potent acetylcholinesterase inhibitors.
Ronco C; Foucault R; Gillon E; Bohn P; Nachon F; Jean L; Renard PY
ChemMedChem; 2011 May; 6(5):876-88. PubMed ID: 21344648
[TBL] [Abstract][Full Text] [Related]
19. NO-donating tacrine derivatives as potential butyrylcholinesterase inhibitors with vasorelaxation activity.
Chen Y; Sun J; Huang Z; Liao H; Peng S; Lehmann J; Zhang Y
Bioorg Med Chem Lett; 2013 Jun; 23(11):3162-5. PubMed ID: 23639542
[TBL] [Abstract][Full Text] [Related]
20. First gallamine-tacrine hybrid: design and characterization at cholinesterases and the M2 muscarinic receptor.
Elsinghorst PW; Cieslik JS; Mohr K; Tränkle C; Gütschow M
J Med Chem; 2007 Nov; 50(23):5685-95. PubMed ID: 17944454
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
