211 related articles for article (PubMed ID: 16942034)
41. Studies on the structure-activity relationship of 2',6'-dimethyl-l-tyrosine (Dmt) derivatives: bioactivity profile of H-Dmt-NH-CH(3).
Fujita Y; Tsuda Y; Motoyama T; Li T; Miyazaki A; Yokoi T; Sasaki Y; Ambo A; Niizuma H; Jinsmaa Y; Bryant SD; Lazarus LH; Okada Y
Bioorg Med Chem Lett; 2005 Feb; 15(3):599-602. PubMed ID: 15664820
[TBL] [Abstract][Full Text] [Related]
42. Synthesis and characterization of potent and selective mu-opioid receptor antagonists, [Dmt(1), D-2-Nal(4)]endomorphin-1 (Antanal-1) and [Dmt(1), D-2-Nal(4)]endomorphin-2 (Antanal-2).
Fichna J; do-Rego JC; Chung NN; Lemieux C; Schiller PW; Poels J; Broeck JV; Costentin J; Janecka A
J Med Chem; 2007 Feb; 50(3):512-20. PubMed ID: 17266203
[TBL] [Abstract][Full Text] [Related]
43. Inhibition of human multidrug resistance P-glycoprotein 1 by analogues of a potent delta-opioid antagonist.
Lovekamp T; Cooper PS; Hardison J; Bryant SD; Guerrini R; Balboni G; Salvadori S; Lazarus LH
Brain Res; 2001 May; 902(1):131-4. PubMed ID: 11376603
[TBL] [Abstract][Full Text] [Related]
44. New series of potent delta-opioid antagonists containing the H-Dmt-Tic-NH-hexyl-NH-R motif.
Li T; Shiotani K; Miyazaki A; Fujita Y; Tsuda Y; Ambo A; Sasaki Y; Jinsmaa Y; Marczak E; Bryant SD; Lazarus LH; Okada Y
Bioorg Med Chem Lett; 2005 Dec; 15(24):5517-20. PubMed ID: 16183273
[TBL] [Abstract][Full Text] [Related]
45. Effect of N-alkyl and N-alkenyl substituents in noroxymorphindole, 17-substituted-6,7-dehydro-4,5alpha-epoxy-3,14-dihydroxy-6,7:2',3'-indolomorphinans, on opioid receptor affinity, selectivity, and efficacy.
McLamore S; Ullrich T; Rothman RB; Xu H; Dersch C; Coop A; Davis P; Porreca F; Jacobson AE; Rice KC
J Med Chem; 2001 Apr; 44(9):1471-4. PubMed ID: 11311071
[TBL] [Abstract][Full Text] [Related]
46. Pharmacological characterization of the bifunctional opioid ligand H-Dmt-Tic-Gly-NH-Bzl (UFP-505).
Dietis N; McDonald J; Molinari S; Calo G; Guerrini R; Rowbotham DJ; Lambert DG
Br J Anaesth; 2012 Feb; 108(2):262-70. PubMed ID: 22194444
[TBL] [Abstract][Full Text] [Related]
47. Structure-activity relationships of bifunctional peptides based on overlapping pharmacophores at opioid and cholecystokinin receptors.
Agnes RS; Lee YS; Davis P; Ma SW; Badghisi H; Porreca F; Lai J; Hruby VJ
J Med Chem; 2006 May; 49(10):2868-75. PubMed ID: 16686530
[TBL] [Abstract][Full Text] [Related]
48. Selective opioid dipeptides.
Temussi PA; Salvadori S; Amodeo P; Bianchi C; Guerrini R; Tomatis R; Lazarus LH; Picone D; Tancredi T
Biochem Biophys Res Commun; 1994 Feb; 198(3):933-9. PubMed ID: 8117299
[TBL] [Abstract][Full Text] [Related]
49. Conversion of delta-, kappa- and mu-receptor selective opioid peptide agonists into delta-, kappa- and mu-selective antagonists.
Schiller PW; Weltrowska G; Nguyen TM; Lemieux C; Chung NN; Lu Y
Life Sci; 2003 Jun; 73(6):691-8. PubMed ID: 12801590
[TBL] [Abstract][Full Text] [Related]
50. Identification of opioid ligands possessing mixed micro agonist/delta antagonist activity among pyridomorphinans derived from naloxone, oxymorphone, and hydromorphone [correction of hydropmorphone].
Ananthan S; Khare NK; Saini SK; Seitz LE; Bartlett JL; Davis P; Dersch CM; Porreca F; Rothman RB; Bilsky EJ
J Med Chem; 2004 Mar; 47(6):1400-12. PubMed ID: 14998329
[TBL] [Abstract][Full Text] [Related]
51. Opiate aromatic pharmacophore structure-activity relationships in CTAP analogues determined by topographical bias, two-dimensional NMR, and biological activity assays.
Bonner GG; Davis P; Stropova D; Edsall S; Yamamura HI; Porreca F; Hruby VJ
J Med Chem; 2000 Feb; 43(4):569-80. PubMed ID: 10691683
[TBL] [Abstract][Full Text] [Related]
52. Design, synthesis, and biological evaluation of novel bifunctional C-terminal-modified peptides for delta/mu opioid receptor agonists and neurokinin-1 receptor antagonists.
Yamamoto T; Nair P; Davis P; Ma SW; Navratilova E; Moye S; Tumati S; Lai J; Vanderah TW; Yamamura HI; Porreca F; Hruby VJ
J Med Chem; 2007 Jun; 50(12):2779-86. PubMed ID: 17516639
[TBL] [Abstract][Full Text] [Related]
53. Differential stereochemical requirements of mu vs. delta opioid receptors for ligand binding and signal transduction: development of a class of potent and highly delta-selective peptide antagonists.
Schiller PW; Nguyen TM; Weltrowska G; Wilkes BC; Marsden BJ; Lemieux C; Chung NN
Proc Natl Acad Sci U S A; 1992 Dec; 89(24):11871-5. PubMed ID: 1334552
[TBL] [Abstract][Full Text] [Related]
54. Dicarba analogues of the cyclic enkephalin peptides H-Tyr-c[D-Cys-Gly-Phe-D(or L)-Cys]NH(2) retain high opioid activity.
Berezowska I; Chung NN; Lemieux C; Wilkes BC; Schiller PW
J Med Chem; 2007 Mar; 50(6):1414-7. PubMed ID: 17315860
[TBL] [Abstract][Full Text] [Related]
55. Role of hydrophobic substituents in the interaction of opioid Tyr-Tic dipeptide analogs with dodecylphosphocholine micelles. Molecular partitioning in model membrane systems.
Carpenter KA; Wilkes BC; Weltrowska G; Schiller PW
Eur J Biochem; 1996 Nov; 241(3):756-64. PubMed ID: 8944763
[TBL] [Abstract][Full Text] [Related]
56. Inhibition of the development of morphine tolerance by a potent dual mu-delta-opioid antagonist, H-Dmt-Tic-Lys-NH-CH2-Ph.
Jinsmaa Y; Marczak ED; Balboni G; Salvadori S; Lazarus LH
Pharmacol Biochem Behav; 2008 Oct; 90(4):651-7. PubMed ID: 18571706
[TBL] [Abstract][Full Text] [Related]
57. Influence of the side chain next to C-terminal benzimidazole in opioid pseudopeptides containing the Dmt-Tic pharmacophore.
Balboni G; Trapella C; Sasaki Y; Ambo A; Marczak ED; Lazarus LH; Salvadori S
J Med Chem; 2009 Sep; 52(17):5556-9. PubMed ID: 19642675
[TBL] [Abstract][Full Text] [Related]
58. Opioid diketopiperazines: refinement of the delta opioid antagonist pharmacophore.
Bryant SD; Balboni G; Guerrini R; Salvadori S; Tomatis R; Lazarus LH
Biol Chem; 1997 Feb; 378(2):107-14. PubMed ID: 9088539
[TBL] [Abstract][Full Text] [Related]
59. Synthesis of opioidmimetics, 3-[H-Dmt-NH(CH(2))(m)]-6-[H-Dmt-NH(CH(2))(n)]-2(1H)-pyrazinones, and studies on structure-activity relationships.
Shiotani K; Miyazaki A; Li T; Tsuda Y; Yokoi T; Ambo A; Sasaki Y; Bryant SD; Jinsmaa Y; Lazarus LH; Okada Y
Med Chem; 2007 Nov; 3(6):583-98. PubMed ID: 18045209
[TBL] [Abstract][Full Text] [Related]
60. Evolution of the Bifunctional Lead μ Agonist / δ Antagonist Containing the Dmt-Tic Opioid Pharmacophore.
Balboni G; Salvadori S; Trapella C; Knapp BI; Bidlack JM; Lazarus LH; Peng X; Neumeyer JL
ACS Chem Neurosci; 2010 Feb; 1(2):155-164. PubMed ID: 20352071
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
