BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

117 related articles for article (PubMed ID: 16942750)

  • 1. Furin is an endogenous regulator of alpha-secretase associated APP processing.
    Hwang EM; Kim SK; Sohn JH; Lee JY; Kim Y; Kim YS; Mook-Jung I
    Biochem Biophys Res Commun; 2006 Oct; 349(2):654-9. PubMed ID: 16942750
    [TBL] [Abstract][Full Text] [Related]  

  • 2. P2Y2 nucleotide receptors enhance alpha-secretase-dependent amyloid precursor protein processing.
    Camden JM; Schrader AM; Camden RE; González FA; Erb L; Seye CI; Weisman GA
    J Biol Chem; 2005 May; 280(19):18696-702. PubMed ID: 15778502
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Muscarinic acetylcholine receptor inhibition in transgenic Alzheimer-like Tg2576 mice by scopolamine favours the amyloidogenic route of processing of amyloid precursor protein.
    Liskowsky W; Schliebs R
    Int J Dev Neurosci; 2006; 24(2-3):149-56. PubMed ID: 16423497
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of TNFalpha-converting enzyme inhibition on amyloid beta production and APP processing in vitro and in vivo.
    Kim ML; Zhang B; Mills IP; Milla ME; Brunden KR; Lee VM
    J Neurosci; 2008 Nov; 28(46):12052-61. PubMed ID: 19005070
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
    Evin G; Zhu A; Holsinger RM; Masters CL; Li QX
    J Neurosci Res; 2003 Nov; 74(3):386-92. PubMed ID: 14598315
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase.
    Asai M; Hattori C; Szabó B; Sasagawa N; Maruyama K; Tanuma S; Ishiura S
    Biochem Biophys Res Commun; 2003 Jan; 301(1):231-5. PubMed ID: 12535668
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Constitutive alpha-secretase cleavage of the beta-amyloid precursor protein in the furin-deficient LoVo cell line: involvement of the pro-hormone convertase 7 and the disintegrin metalloprotease ADAM10.
    Lopez-Perez E; Zhang Y; Frank SJ; Creemers J; Seidah N; Checler F
    J Neurochem; 2001 Mar; 76(5):1532-9. PubMed ID: 11238737
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enhancement of alpha-secretase cleavage of amyloid precursor protein by a metalloendopeptidase nardilysin.
    Hiraoka Y; Ohno M; Yoshida K; Okawa K; Tomimoto H; Kita T; Nishi E
    J Neurochem; 2007 Sep; 102(5):1595-1605. PubMed ID: 17555553
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-golgi network.
    Skovronsky DM; Moore DB; Milla ME; Doms RW; Lee VM
    J Biol Chem; 2000 Jan; 275(4):2568-75. PubMed ID: 10644715
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel alpha-secretase cleavage of Alzheimer's amyloid beta precursor protein in the endoplasmic reticulum of COS7 cells.
    Shin RW; Saido TC; Maeda M; Kitamoto T
    Neurosci Lett; 2005 Mar; 376(1):14-9. PubMed ID: 15694266
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chronic hypoxia in the human neuroblastoma SH-SY5Y causes reduced expression of the putative alpha-secretases, ADAM10 and TACE, without altering their mRNA levels.
    Marshall AJ; Rattray M; Vaughan PF
    Brain Res; 2006 Jul; 1099(1):18-24. PubMed ID: 16762326
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate-induced alpha-secretase cleavage of amyloid precursor protein.
    Obregon DF; Rezai-Zadeh K; Bai Y; Sun N; Hou H; Ehrhart J; Zeng J; Mori T; Arendash GW; Shytle D; Town T; Tan J
    J Biol Chem; 2006 Jun; 281(24):16419-27. PubMed ID: 16624814
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Huperzine A regulates amyloid precursor protein processing via protein kinase C and mitogen-activated protein kinase pathways in neuroblastoma SK-N-SH cells over-expressing wild type human amyloid precursor protein 695.
    Peng Y; Lee DY; Jiang L; Ma Z; Schachter SC; Lemere CA
    Neuroscience; 2007 Dec; 150(2):386-95. PubMed ID: 17945434
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein.
    Allinson TM; Parkin ET; Condon TP; Schwager SL; Sturrock ED; Turner AJ; Hooper NM
    Eur J Biochem; 2004 Jun; 271(12):2539-47. PubMed ID: 15182369
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Shedding of the amyloid precursor protein-like protein APLP2 by disintegrin-metalloproteinases.
    Endres K; Postina R; Schroeder A; Mueller U; Fahrenholz F
    FEBS J; 2005 Nov; 272(22):5808-20. PubMed ID: 16279945
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The search for alpha-secretase and its potential as a therapeutic approach to Alzheimer s disease.
    Hooper NM; Turner AJ
    Curr Med Chem; 2002 Jun; 9(11):1107-19. PubMed ID: 12052175
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Phosphorylation of amyloid precursor carboxy-terminal fragments enhances their processing by a gamma-secretase-dependent mechanism.
    Vingtdeux V; Hamdane M; Gompel M; Bégard S; Drobecq H; Ghestem A; Grosjean ME; Kostanjevecki V; Grognet P; Vanmechelen E; Buée L; Delacourte A; Sergeant N
    Neurobiol Dis; 2005 Nov; 20(2):625-37. PubMed ID: 15936948
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model.
    Postina R; Schroeder A; Dewachter I; Bohl J; Schmitt U; Kojro E; Prinzen C; Endres K; Hiemke C; Blessing M; Flamez P; Dequenne A; Godaux E; van Leuven F; Fahrenholz F
    J Clin Invest; 2004 May; 113(10):1456-64. PubMed ID: 15146243
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Octyl gallate markedly promotes anti-amyloidogenic processing of APP through estrogen receptor-mediated ADAM10 activation.
    Zhang SQ; Sawmiller D; Li S; Rezai-Zadeh K; Hou H; Zhou S; Shytle D; Giunta B; Fernandez F; Mori T; Tan J
    PLoS One; 2013; 8(8):e71913. PubMed ID: 23977176
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.