BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

133 related articles for article (PubMed ID: 16946405)

  • 1. PPAR gamma ligand troglitazone lowers cholesterol synthesis in HepG2 and Caco-2 cells via a reduced concentration of nuclear SREBP-2.
    Klopotek A; Hirche F; Eder K
    Exp Biol Med (Maywood); 2006 Sep; 231(8):1365-72. PubMed ID: 16946405
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of PPARalpha lowers synthesis and concentration of cholesterol by reduction of nuclear SREBP-2.
    König B; Koch A; Spielmann J; Hilgenfeld C; Stangl GI; Eder K
    Biochem Pharmacol; 2007 Feb; 73(4):574-85. PubMed ID: 17126302
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PPAR gamma ligands, troglitazone and pioglitazone, up-regulate expression of HMG-CoA synthase and HMG-CoA reductase gene in THP-1 macrophages.
    Iida KT; Kawakami Y; Suzuki H; Sone H; Shimano H; Toyoshima H; Okuda Y; Yamada N
    FEBS Lett; 2002 Jun; 520(1-3):177-81. PubMed ID: 12044893
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of PPARalpha and PPARgamma reduces triacylglycerol synthesis in rat hepatoma cells by reduction of nuclear SREBP-1.
    König B; Koch A; Spielmann J; Hilgenfeld C; Hirche F; Stangl GI; Eder K
    Eur J Pharmacol; 2009 Mar; 605(1-3):23-30. PubMed ID: 19248225
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Polyphenol-rich black chokeberry (Aronia melanocarpa) extract regulates the expression of genes critical for intestinal cholesterol flux in Caco-2 cells.
    Kim B; Park Y; Wegner CJ; Bolling BW; Lee J
    J Nutr Biochem; 2013 Sep; 24(9):1564-70. PubMed ID: 23517916
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Troglitazone, an antidiabetic agent, inhibits cholesterol biosynthesis through a mechanism independent of peroxisome proliferator-activated receptor-gamma.
    Wang M; Wise SC; Leff T; Su TZ
    Diabetes; 1999 Feb; 48(2):254-60. PubMed ID: 10334298
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Scavenger receptor CD36 mediates inhibition of cholesterol synthesis via activation of the PPARγ/PGC-1α pathway and Insig1/2 expression in hepatocytes.
    Rodrigue-Way A; Caron V; Bilodeau S; Keil S; Hassan M; Lévy E; Mitchell GA; Tremblay A
    FASEB J; 2014 Apr; 28(4):1910-23. PubMed ID: 24371122
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of sterol regulatory element-binding proteins by cholesterol flux in CaCo-2 cells.
    Field FJ; Born E; Murthy S; Mathur SN
    J Lipid Res; 2001 Oct; 42(10):1687-98. PubMed ID: 11590226
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Troglitazone, a peroxisome proliferator-activated receptor gamma ligand, induces growth inhibition and apoptosis of HepG2 human liver cancer cells.
    Zhou YM; Wen YH; Kang XY; Qian HH; Yang JM; Yin ZF
    World J Gastroenterol; 2008 Apr; 14(14):2168-73. PubMed ID: 18407589
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comparison of cytokine modulation by natural peroxisome proliferator-activated receptor gamma ligands with synthetic ligands in intestinal-like Caco-2 cells and human dendritic cells--potential for dietary modulation of peroxisome proliferator-activated receptor gamma in intestinal inflammation.
    Marion-Letellier R; Butler M; Déchelotte P; Playford RJ; Ghosh S
    Am J Clin Nutr; 2008 Apr; 87(4):939-48. PubMed ID: 18400717
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Increased gene expression of liver SREBP-2 in experimental chronic renal failure.
    Chmielewski M; Sucajtys-Szulc E; Kossowska E; Swierczynski J; Rutkowski B; Boguslawski W
    Atherosclerosis; 2007 Apr; 191(2):326-32. PubMed ID: 16814791
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) agonist inhibits transforming growth factor-beta1 and matrix production in human dermal fibroblasts.
    Zhang GY; Cheng T; Zheng MH; Yi CG; Pan H; Li ZJ; Chen XL; Yu Q; Jiang LF; Zhou FY; Li XY; Yang JQ; Chu TG; Gao WY
    J Plast Reconstr Aesthet Surg; 2010 Jul; 63(7):1209-16. PubMed ID: 19617014
    [TBL] [Abstract][Full Text] [Related]  

  • 13. LDL receptor gene transcription is selectively induced by t10c12-CLA but not by c9t11-CLA in the human hepatoma cell line HepG2.
    Ringseis R; König B; Leuner B; Schubert S; Nass N; Stangl G; Eder K
    Biochim Biophys Acta; 2006 Oct; 1761(10):1235-43. PubMed ID: 16982210
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Peroxisome proliferator-activated receptor (PPAR)-gamma expression in human vascular smooth muscle cells: inhibition of growth, migration, and c-fos expression by the peroxisome proliferator-activated receptor (PPAR)-gamma activator troglitazone.
    Benson S; Wu J; Padmanabhan S; Kurtz TW; Pershadsingh HA
    Am J Hypertens; 2000 Jan; 13(1 Pt 1):74-82. PubMed ID: 10678274
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bisphenol A induces cholesterol biosynthesis in HepG2 cells via SREBP-2/HMGCR signaling pathway.
    Li Q; Zhang H; Zou J; Feng X; Feng D
    J Toxicol Sci; 2019; 44(7):481-491. PubMed ID: 31270304
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Unique ability of troglitazone to up-regulate peroxisome proliferator-activated receptor-gamma expression in hepatocytes.
    Davies GF; McFie PJ; Khandelwal RL; Roesler WJ
    J Pharmacol Exp Ther; 2002 Jan; 300(1):72-7. PubMed ID: 11752099
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Troglitazone inhibits synthesis of transforming growth factor-beta1 and reduces matrix production in human peritoneal mesothelial cells.
    Peng Y; Liu H; Liu F; Liu Y; Li J; Chen X
    Nephrology (Carlton); 2006 Dec; 11(6):516-23. PubMed ID: 17199790
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Growth arrest by troglitazone is mediated by p27Kip1 accumulation, which results from dual inhibition of proteasome activity and Skp2 expression in human hepatocellular carcinoma cells.
    Motomura W; Takahashi N; Nagamine M; Sawamukai M; Tanno S; Kohgo Y; Okumura T
    Int J Cancer; 2004 Jan; 108(1):41-6. PubMed ID: 14618613
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hepatic farnesyl diphosphate synthase expression is suppressed by polyunsaturated fatty acids.
    Le Jossic-Corcos C; Gonthier C; Zaghini I; Logette E; Shechter I; Bournot P
    Biochem J; 2005 Feb; 385(Pt 3):787-94. PubMed ID: 15473864
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Up-regulation of peroxisome proliferator-activated receptors (PPAR-alpha) and PPAR-gamma messenger ribonucleic acid expression in the liver in murine obesity: troglitazone induces expression of PPAR-gamma-responsive adipose tissue-specific genes in the liver of obese diabetic mice.
    Memon RA; Tecott LH; Nonogaki K; Beigneux A; Moser AH; Grunfeld C; Feingold KR
    Endocrinology; 2000 Nov; 141(11):4021-31. PubMed ID: 11089532
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.